Missouri Luxury Vacations

Book a Luxury Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ₩234,741 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Top Luxury Missouri Hotels

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
  • 34 min drive from St. Louis Union Station
The price is ₩262,066 per night from Feb 1 to Feb 2
₩262,066
₩330,574 total
Feb 1 - Feb 2
includes taxes & fees
Stay in the lap of luxury at Ameristar Casino Resort and Spa, where you can enjoy amenities like plush bedding, HDTVs, and more. Notable amenities include a ...
8.4/10 Very Good! (1,003 reviews)
Excellent staff

Reviewed on Jan 23, 2026

Ameristar Casino Resort and Spa
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

5 out of 5
999 North Second Street St. Louis MO
  • 20 min walk from St. Louis Union Station
The price is ₩607,245 per night from Jan 26 to Jan 27
₩607,245
₩710,038 total
Jan 26 - Jan 27
includes taxes & fees
Be treated to deluxe lodging at Four Seasons Hotel St Louis, where you'll find deep soaking bathtubs and a champagne service. Notable amenities include a spa, ...
9.4/10 Exceptional! (1,001 reviews)
Our room was excellent. Staff super attentive. Restaurant and bar were outstanding. Will definitely be back again.

Reviewed on Jan 16, 2026

Four Seasons Hotel St Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
  • 13 min drive from St. Louis Union Station
The price is ₩133,005 per night from Jan 30 to Jan 31
₩133,005
₩155,275 total
Jan 30 - Jan 31
includes taxes & fees
Choose luxury at Clayton Plaza Hotel & Extended Stay, where you can enjoy amenities like pillowtop beds, HDTVs, and more. Notable amenities include a heated ...
8.8/10 Excellent! (3,081 reviews)
Very nice hotel. Great location, excellent free breakfast, the shower was wonderful, and the bed was so comfortable.

Reviewed on Jan 22, 2026

Clayton Plaza Hotel & Extended Stay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.