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Top Luxury Central Mississippi Hotels

Microtel Inn & Suites by Wyndham Meridian

518 Bonita Lakes Dr Meridian MS

3 hours drive from Mississippi State University

Microtel Inn & Suites by Wyndham Meridian provides luxe lodging where you'll enjoy premium channels and more.

6.2/10 (1,003 reviews)

Room was clean and tidy

Reviewed on Dec 29, 2025

Red Roof Inn Meridian

2219 S Frontage Rd Meridian MS

3 hours drive from Mississippi State University

Treat yourself to some luxurious accommodations at Red Roof Inn Meridian, where you can enjoy amenities like premium channels, flat-screen TVs, and more.

6.4/10 (935 reviews)

Room is old and needs remodeling but was clean and acceptable to sleep in.

Reviewed on Dec 29, 2025

Comfort Inn & Suites Columbus North

129 Brickerton St Columbus MS

32 min drive from Mississippi State University

Discover luxurious lodging at Comfort Inn & Suites Columbus North, where you can enjoy amenities like plush bedding, premium channels, and more. Deluxe amenities ...

7.2/10 Good! (817 reviews)

Staff very nice, rooms and hotel clean, hot water. Breakfast decent (standard breakfast). The ONLY thing I could say is negative is that the indoor swimming pool was out of order. It wasn’t a deal breaker or anything like that BUT I think if the pool is not in working order that should be disclosed. ...

Reviewed on Jan 3, 2026

See all 442 properties in Central Mississippi

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.