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Top Luxury Panhandle Plains Hotels

Studio 6 Amarillo, TX – West Medical Center

6801 W Interstate 40 Amarillo TX

4 hours drive from Texas Tech University

Treat yourself to some luxurious accommodations at Studio 6 Amarillo, TX – West Medical Center, where you can enjoy amenities like pillowtop beds, designer toiletries, ...

7.4/10 Good! (1,009 reviews)

Room clean enough. Breakfast was supposed to be serverd till 9:30. Went down at 9 & it was already closed up.

Reviewed on Nov 23, 2025

Spark by Hilton Amarillo East

2301 East I40 Amarillo TX

4 hours drive from Texas Tech University

Indulge yourself with classy lodging with a stay at Spark by Hilton Amarillo East, where you'll enjoy amenities like premium bedding and more. Notable amenities ...

8.8/10 Excellent! (218 reviews)

The hotel was clean

Reviewed on Dec 1, 2025

Hawthorn Suites by Wyndham Lubbock

4435 Marsha Sharp Fwy Lubbock TX

25 min walk from Texas Tech University

Hawthorn Suites by Wyndham Lubbock provides luxe lodging where you'll enjoy pillowtop beds and more. The indoor pool, fitness center, and hot tub are just some ...

7.8/10 Good! (1,008 reviews)

Welcoming check in and clean room! Also, breakfast was decent,

Reviewed on Nov 25, 2025

See all 2,158 properties in Panhandle Plains

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.