Eastern South Dakota Luxury Vacations 2026

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Top Luxury Eastern South Dakota Hotels

Baymont by Wyndham Sioux Falls West (67058) Sioux/ Near Airport

3101 W Russell St Sioux Falls SD

25 min walk from Denny Sanford Premier Center

Be treated to luxurious accommodations at Baymont by Wyndham Sioux Falls West (67058) Sioux/ Near Airport, where you can enjoy amenities like hydromassage showers, ...

7/10 Good! (1,010 reviews)

"Older property overall. With some improvements. Rooms were musty smelling. Stickers of social distancing still on the floor from 2020, could not open bathroom door all the way because of elongated stool blocking the opening of the door completely. would like to have coffee available in lobby at all ..."

Reviewed on Sep 29, 2026

Econo Lodge Sioux Falls Empire Mall

3500 Gateway Boulevard Sioux Falls SD

9 min drive from Denny Sanford Premier Center

Stay in the lap of luxury at Econo Lodge Sioux Falls Empire Mall, where you can enjoy amenities like premium channels, flat-screen TVs, and more.

7/10 Good! (442 reviews)

Economy hotel, no thrills, but it's nice

"Staff was really nice. Rooms are spacious. Good value and convenient to many stores/restaurants, etc. Rooms for clean."

Reviewed on Oct 18, 2022

My Place Hotel - Sioux Falls, SD

3005 S. Carolyn Ave Sioux Falls SD

8 min drive from Denny Sanford Premier Center

Go for a luxurious stay at My Place Hotel - Sioux Falls, SD, where you can enjoy amenities like pillowtop beds, premium channels, and more.

8.6/10 Excellent! (1,011 reviews)

"It was very clean. Useful little kitchenette. Ice maker worked!!! Great service from staff."

Reviewed on Sep 29, 2026

See all 1,004 properties in Eastern South Dakota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.