Central United States Luxury Vacations 2026

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Top Luxury Central United States Hotels

The Peabody Memphis

149 Union Avenue Memphis TN

11 hours drive from Great Smoky Mountains National Park

Be treated to luxurious accommodations at The Peabody Memphis, where you can enjoy amenities like 24-hour room service, pillowtop beds, and more. The 2 bars, ...

9.4/10 Exceptional! (1,002 reviews)

"Very enjoyable short vacation, although the place suffered from too much success! It was very crowded with folks who were not apparently hotel guests. Otherwise, a good time."

Reviewed on Sep 18, 2026

The St. Anthony, A Luxury Collection Hotel, San Antonio

300 E Travis St San Antonio TX

25 hours drive from Great Smoky Mountains National Park

Be treated to luxurious accommodations at The St. Anthony, A Luxury Collection Hotel, San Antonio, where you can enjoy amenities like pillowtop beds, designer ...

Hotel Viata

320 S. Capital of Texas Hwy, Bldg. B Austin TX

Go for a luxurious stay at Hotel Viata, where you can enjoy amenities like Champagne service, plush bedding, and more. Deluxe amenities at this hotel include ...

9.2/10 Wonderful! (967 reviews)

"The hotel is not necessarily a resort but it is more than a hotel. It is very clean, the staff is friendly and helpful, and the food is so good. The pool and spa look nice, although, I didn’t make use of either for this stay. There is free covered parking. The views are nice and the room comfortable. ..."

Reviewed on Sep 17, 2026

See all 319,228 properties in Central United States

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.