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Top Luxury North Central Florida Hotels

Baymont By Wyndham Gainesville I-75

6901 NW 4th Boulevard Gainesville FL

21 min walk from University of Florida

Baymont By Wyndham Gainesville I-75 awaits for a deluxe vacation.

5.2/10 (1,000 reviews)

All that was good but need to pay more attention to pot being smoked all over the motel

Reviewed on Mar 9, 2026

Palms Garden Inn

14113 S. US Hwy 441 Lake City FL

58 min drive from University of Florida

Discover luxurious lodging at Palms Garden Inn, where you can enjoy amenities like plush bedding, premium channels, and more.

7.4/10 Good! (592 reviews)

Clean room & comfortable bed. Will definitely book at this hotel again!

Reviewed on Mar 9, 2026

Americas Best Value Inn Lake City

3835 West US Highway 90 Lake City FL

1 hour drive from University of Florida

Choose luxury at Americas Best Value Inn Lake City, where you can enjoy amenities like premium channels, flat-screen TVs, and more. The outdoor pool and pool ...

8.6/10 Excellent! (1,002 reviews)

Clean room, hot shower. Beds were meh, property slightly rundown, but for the $$ 3.5 stars

Reviewed on Mar 10, 2026

See all 2,692 properties in North Central Florida

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.