Upstate South Carolina Romantic Vacations
Book a Romantic Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to ₩1,660,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Top Romantic Upstate South Carolina Hotels
Greenville Marriott
One Parkway E Greenville SC
- 2 hours drive from Clemson University
Rekindle the romance with your special someone. Consider booking a getaway at this hotel where you're sure to love the premium mattresses and luxury bedding. ...
Hotel Domestique
10 Road of Vines Travelers Rest SC
- 2 hours drive from Clemson University
Indulge in a romantic getaway at this boutique hotel, where you'll find spa services, in-room massages, and a garden. Couples will love the lobby fireplace and ...
9.8/10 Exceptional! (35 reviews)
Couples like: onsite spa services, bar, champagne service, romance packages available
Travelers say...
"Property is amazing! Beautiful views! Excellent restaurant! Wonderful staff! Very welcoming to our dog too! One of the most comfortable beds we have had at a hotel."
Reviewed on Aug 6, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
