The Best Business Hotels in Central Iowa, IA from ₩100,548 in 2026

A historic building with a large central archway and a pond in the foreground.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check availability on Central Iowa Business Hotels

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Central Iowa business-friendly hotels

An indoor swimming pool with a hot tub, tiled flooring, and seating area with chairs and potted plants.

A lobby with a large banner of Iowa State University Central Campus, seating area with sofas and tables, and a staircase leading to upper floors.

A modern hotel room with a central seating area, a flat-screen TV, and a large window with curtains.

A hotel room with two beds, a desk, a chair, and a TV.

1. Gateway Hotel and Conference Center at Iowa State University

Ames

Darren

₩132,834

₩148,785 total

includes taxes & fees

Oct 18 - Oct 19

A lobby with a fireplace, seating area, and a reception desk.

A lobby with a fireplace, green and blue sofas, a flat-screen TV, and a reception desk.

A lobby with blue armchairs, a wooden table, and a brick wall.

A hotel room with a bed, a nightstand, a mirror, and a wall-mounted lamp.

2. Comfort Inn and Suites Ames near ISU Campus

Ames

Rachelle

₩136,924

₩153,355 total

includes taxes & fees

Oct 20 - Oct 21

A modern dining area with a long table, patterned chairs, and hanging pendant lights.

A hotel reception area with a counter, framed pictures, and a vending machine.

A Hampton Inn & Suites hotel entrance with a stone facade, a large illuminated sign, and a number 2100 displayed above the entrance.

A snack display area with shelves stocked with various treats.

3. Hampton Inn & Suites Ames

Ames

Michelle

₩133,240

₩149,229 total

includes taxes & fees

Oct 4 - Oct 5

A spacious living area with a wooden dining table, comfortable seating, a brick fireplace, and a staircase leading to an upper level.

A spacious lobby with a reception desk, a dining area, and a staircase leading to upper floors.

An indoor swimming pool with a blue water feature, a tiled floor, and a seating area with chairs and a plant.

A gym with exercise equipment, a mirror, and a rack of dumbbells.

4. Best Western Plus University Park Inn & Suites

Ames

Mandy

₩128,122

₩143,496 total

includes taxes & fees

Oct 4 - Oct 5

5. Microtel Inn & Suites by Wyndham Ames

Ames

Douglas

₩103,586

₩116,017 total

includes taxes & fees

Sep 28 - Sep 29

A hotel room with a large bathtub, a sofa, a desk with a television, and a window with curtains.

A buffet setup with various food items and a 'RISE & SHINE' sign on the wall.

A hotel corridor with a Coca-Cola vending machine and a water dispenser.

An indoor swimming pool with clear blue water, surrounded by seating areas and windows.

6. Comfort Inn Story City

Story City

keith

₩124,304

₩139,220 total

includes taxes & fees

Oct 18 - Oct 19

A modern dining area with a kitchen in the background, a flat-screen TV displaying "Free Wi-Fi All Rooms", and a ceiling fan.

A hotel room with a desk, chair, TV, lamp, and a mirror.

A hotel room with a bed, a desk, a chair, a sofa, and a TV.

A Sonesta Essential Hotel with a modern design, featuring a large entrance and a parking lot.

7. Sonesta Essential Ames

Ames

Bertis

₩89,775

₩100,548 total

includes taxes & fees

Oct 5 - Oct 6

A spacious lobby with a brown sofa, armchairs, and a coffee table.

A hotel room with a bed, a sofa, a desk, and a chair. There are three framed pictures on the wall.

A reception area with a wooden reception desk, a computer, and a wall-mounted sign.

A spacious hotel dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and a large window providing a view of the cityscape.

8. Sleep Inn & Suites Ames near ISU Campus

Ames

Melissa

₩119,700

₩134,064 total

includes taxes & fees

Oct 11 - Oct 12

View all properties

Top Central Iowa Hotel Reviews

Days Inn & Suites by Wyndham Des Moines Airport

8/10 Good

"Room was clean. I got in later so I could catch an early flight."

Fairfield Inn and Suites by Marriott Des Moines West

10/10 Excellent

"Ckean room friendly staff"

Des Lux Hotel

10/10 Excellent

"One of the most elegant hotels on the planet. Likely the best all around in Iowa. Amazing in every way."

Des Moines Marriott Downtown

10/10 Excellent

"Clean place"

Best Western Plus University Park Inn & Suites

10/10 Excellent

"The staff does not dress professionally, but don't let that fool you. They do a great job."

Motel 6 Des Moines, IA - North

10/10 Excellent

"It’s a clean comfortable room for a low price."

Frequently asked questions

How much do business-friendly hotels in Central Iowa cost?

Business-friendly hotels in Central Iowa range between ₩100,548 and ₩153,355 per night. This means you can lock in a stay with useful amenities like workspaces and WiFi at a price that won't stretch the work budget. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

What are the best business-friendly hotels in Central Iowa?

Central Iowa offers multiple business-friendly hotels with a total average guest review rating of 8.6. Attending a meeting in Des Moines? Surety Hotel is a 4-stars property that's preferred by corporate travelers and features dining romance packages and an outdoor entertainment area. Another excellent choice for a business trip is Staybridge Suites Des Moines Downtown, an IHG Hotel. Also located in Des Moines, it has a 3-stars rating and amenities such as a barbecue grill and a swimming pool.

How many business-friendly hotels are there in Central Iowa?

Select from 247 business-friendly hotels in Central Iowa. When you need to get down to work, Expedia can help you secure the perfect space with the amenities you want.

What are the best cheap business-friendly hotels in Central Iowa?

That depends on where in Central Iowa you plan to visit. If you need to be in Des Moines, Fairfield Inn & Suites Des Moines Altoona combines business-friendly amenities with affordability. A swimming pool and a tennis court are among its many conveniences. Making a stop in West Des Moines? Book a room at Holiday Inn Express & Suites West Des Moines - Jordan Creek, an IHG Hotel. A swimming pool and WiFi help make this cheaper option a top pick for corporate guests. Business-friendly hotels start at only ₩100,548 per night, so your next work trip doesn't have to cost a lot. You'll find lots of free and fun things to do wherever you choose to go in Central Iowa. If your business trip is taking you to Des Moines, try to find time to visit Des Moines Art Center. You can also go sightseeing without spending a dime in West Des Moines. Des Moines Art Center is one of the most popular free things to do here. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

Are there any family-friendly hotels in Central Iowa that are also business friendly?

You'll discover some terrific family-friendly hotels that are also business friendly in Central Iowa. If you're heading to Des Moines, have a look at Home2 Suites by Hilton Des Moines at Drake University. It offers conveniences such as complimentary breakfast and a firepit and has a 3-stars rating. Alternatively, consider Baymont by Wyndham Des Moines Airport. This 2.5-stars stay in Des Moines is perfect for both leisure and business travelers and features a nearby theme park, a sauna and lots more. Des Moines has plenty of family-friendly attractions when it's time to get out and explore. Adventureland and Blank Park Zoo promise fun for the whole crew.

Why book your business-friendly hotel in Central Iowa with Expedia?

We're here to help you find a fantastic business-friendly hotel when work takes you on the road. From meeting rooms and conference spaces to on-site cafés and more, our stays come with the conveniences you need to get the job done.

How can I find cheap business-friendly hotels in Central Iowa?

When you're traveling for work in Central Iowa, our "business friendly" filter will help you find a suitable hotel. From free WiFi to concierge services and conference spaces, they have the amenities you need to be productive. You can also refine your search by your preferred star rating and budget to see the most affordable properties.

What is there to do in Central Iowa near my business-friendly hotel?

No matter your interests, there are plenty of ways to fill your downtime in Central Iowa. If you're off to Des Moines, stop by Hoyt Sherman Place, Science Center of Iowa and State Historical Museum of Iowa. Planning a stay in West Des Moines? Living History Farms, Pump It Up and Valley Stadium are popular attractions in this city.

Explore a world of travel with Expedia

Book Business Hotels in Central Iowa on Expedia.com

Room 1

Change your mind

Treat yourself

Be picky

Check availability on Central Iowa Business Hotels

Our top choices for Central Iowa business-friendly hotels

1. Gateway Hotel and Conference Center at Iowa State University