Find hotels in Downtown, Seneca

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Downtown hotels

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
2.5 star property
25 km from Downtown
9.0 out of 10, Wonderful, (586 reviews)
"It was great. Room was clean and staff was friendly. "
United States
Veronica
The price is ₩150,288
₩166,818 total
includes taxes & fees
Jan 17 - Jan 18
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
8.6 km from Downtown
9.0 out of 10, Wonderful, (1,000 reviews)
"Great place to stay. "
United States
Gene
The price is ₩159,043
₩197,432 total
includes taxes & fees
Jan 14 - Jan 15
Lakeside Lodge Clemson

Hampton Inn & Suites Lavonia

Hampton Inn & Suites Lavonia
2.5 star property
30.7 km from Downtown
9.0 out of 10, Wonderful, (383 reviews)
"Room was clean and staff was very friendly."
United States
clay
The price is ₩167,460
₩199,922 total
includes taxes & fees
Feb 7 - Feb 8
Hampton Inn & Suites Lavonia

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson
2.0 star property
25.6 km from Downtown
7.8 out of 10, Good, (1,002 reviews)
"Very nice we'll stay there again"
United States
Michael
The price is ₩91,778
₩101,873 total
includes taxes & fees
Jan 18 - Jan 19
Days Inn by Wyndham Anderson

Holiday Inn Anderson by IHG

Holiday Inn Anderson by IHG
3.0 star property
29.5 km from Downtown
8.8 out of 10, Excellent, (700 reviews)
"Clean, great breakfast, convenient location"
United States
Reggie
The price is ₩146,869
₩163,025 total
includes taxes & fees
Feb 9 - Feb 10
Holiday Inn Anderson by IHG

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
15.2 km from Downtown
9.8 out of 10, Exceptional, (791 reviews)
"Clean room, great location, wonderful staff!"
United States
Joyce
The price is ₩217,407
₩241,322 total
includes taxes & fees
Jan 14 - Jan 15
The Inn at Patrick Square

Hilton Garden Inn Anderson

Hilton Garden Inn Anderson
3.0 star property
25.7 km from Downtown
9.0 out of 10, Wonderful, (691 reviews)
"Rooms were clean, staff were friendly, and we had 2 good night’s sleep."
United States
Sadie
The price is ₩154,345
₩171,323 total
includes taxes & fees
Jan 22 - Jan 23
Hilton Garden Inn Anderson

Comfort Suites Anderson-Clemson

Comfort Suites Anderson-Clemson
2.5 star property
25.3 km from Downtown
8.4 out of 10, Very Good, (1,000 reviews)
"Everything was Great very friendly people "
United States
jose
The price is ₩143,139
₩158,884 total
includes taxes & fees
Jan 18 - Jan 19
Comfort Suites Anderson-Clemson

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
11.7 km from Downtown
8.2 out of 10, Very Good, (1,002 reviews)
"Clean and convenient "
United States
Olga
The price is ₩149,705
₩166,172 total
includes taxes & fees
Jan 20 - Jan 21
Comfort Inn & Suites Clemson - University Area

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
11.8 km from Downtown
8.2 out of 10, Very Good, (1,000 reviews)
"Clean room and staff were great’"
United States
Audrey
The price is ₩138,907
₩154,186 total
includes taxes & fees
Jan 18 - Jan 19
Best Western Plus Clemson Hotel & Conference Center

Inn @ Clemson

Inn @ Clemson
2.5 star property
11.6 km from Downtown
8.0 out of 10, Very Good, (1,006 reviews)
"Staff and hotel was amazing "
United States
Keren
Inn @ Clemson

Country Inn & Suites by Radisson, Anderson, SC

Country Inn & Suites by Radisson, Anderson, SC
2.5 star property
25.2 km from Downtown
8.4 out of 10, Very Good, (1,000 reviews)
"Everything was clean and breakfast was a nice spread. "
United States
Sheri
The price is ₩169,403
₩188,037 total
includes taxes & fees
Jan 21 - Jan 22
Country Inn & Suites by Radisson, Anderson, SC

Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson
2.0 star property
24.8 km from Downtown
8.2 out of 10, Very Good, (1,002 reviews)
"Room was clean, front desk people were very nice. "
United States
Caressa
The price is ₩110,382
₩122,524 total
includes taxes & fees
Jan 15 - Jan 16
Microtel Inn & Suites by Wyndham Anderson/Clemson

Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG
2.5 star property
12.4 km from Downtown
8.8 out of 10, Excellent, (954 reviews)
"Staff"
United States
barry
The price is ₩179,471
₩199,210 total
includes taxes & fees
Feb 1 - Feb 2
Holiday Inn Express & Suites Clemson by IHG

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
10.6 km from Downtown
9.8 out of 10, Exceptional, (747 reviews)
"Beautiful hotel. Great service. Delicious food. "
United States
Shannon
The price is ₩261,181
₩289,911 total
includes taxes & fees
Jan 18 - Jan 19
The Shepherd Hotel Downtown Clemson

Baymont by Wyndham Anderson Clemson

Baymont by Wyndham Anderson Clemson
2.5 star property
25 km from Downtown
7.0 out of 10, Good, (849 reviews)
"Well lit parking and safe area around the hotel"
United States
Gregory
The price is ₩86,817
₩96,368 total
includes taxes & fees
Jan 25 - Jan 26
Baymont by Wyndham Anderson Clemson

Fairfield Inn & Suites by Marriott Anderson Clemson

Fairfield Inn & Suites by Marriott Anderson Clemson
2.5 star property
25 km from Downtown
9.0 out of 10, Wonderful, (567 reviews)
"Clean room staff was verynice!"
United States
Laura Jo
The price is ₩129,861
₩144,146 total
includes taxes & fees
Jan 25 - Jan 26
Fairfield Inn & Suites by Marriott Anderson Clemson

Rodeway Inn Anderson North - Clemson

Rodeway Inn Anderson North - Clemson
2.0 star property
25.5 km from Downtown
7.8 out of 10, Good, (319 reviews)
"Room was spotless an the stay was great."
United States
Benito
The price is ₩80,616
₩89,483 total
includes taxes & fees
Feb 13 - Feb 14
Rodeway Inn Anderson North - Clemson

Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast
4.0 star property
16.3 km from Downtown
10.0 out of 10, Exceptional, (78 reviews)
"The owners are amazing. Comfy rooms, stellar breakfast and good people. "
United States
Renee
The price is ₩203,334
₩299,134 total
includes taxes & fees
Jan 16 - Jan 17
Liberty Hall Bed and Breakfast

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
8.3 km from Downtown
9.2 out of 10, Wonderful, (803 reviews)
"Perfect stay for a weekend. Lots of shopping and restaurants nearby. Clean safe area annd the staff was wonderful!"
United States
Cindy
The price is ₩153,280
₩168,609 total
includes taxes & fees
Jan 25 - Jan 26
Tru by Hilton Seneca Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown

Find the best Downtown areas and neighborhoods for the activities you enjoy most.

Serenity Bay

Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.

Pine Ridge Point

While Pine Ridge Point isn't home to many top sights, South Beach and Lake Keowee are some notable places to visit nearby.

Indian Oaks

While there might not be top attractions in Indian Oaks, you can explore the larger area and discover places like Oconee County Library Seneca Branch and Seneca Historic District.

Keowee Plantation

When in Keowee Plantation, you can plan a visit to Oconee County Library Seneca Branch and Seneca Historic District, some noteworthy sights in the nearby area.

Top Downtown Hotel Reviews

Frequently asked questions

What is Downtown like?
Travelers to the Downtown neighborhood in Seneca will be sure to enjoy their stay. Be sure to check out Seneca Historic District and Oconee County Library Seneca Branch as part of your Downtown travel plans.
Where is the best place to stay in Downtown?
Based on Expedia customer reviews, Quality Inn Seneca Clemson Area US-123 is the highest ranked property in Downtown. This hotel offers free breakfast and free parking.
How many hotels can I expect to find in Downtown?
Expedia has 9 Downtown hotels and other accommodations, and one might make a good home base for venturing out into the greater Seneca area.
If I need to cancel my hotel reservation in Downtown, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to view the best deals in Downtown.
Where can I learn more about changing or cancelling my trip to Downtown?
To find more details about rescheduling or cancelling your trip to Downtown, head over to our customer service page.
What can I see and do in this Seneca neighborhood?
Seneca Historic District, Oconee County Library Seneca Branch, and Bertha Lee Strickland Cultural Museum are just a few attractions to check out in Downtown. As you're discovering the neighborhood, The Gauntlet and Seneca City Hall are some other places worth a visit. Golden Corner Plaza, Oconee Community Theatre, and Applewood Shopping Center are just a few of the places to visit in and around Downtown. While you're out sightseeing in Seneca, be sure to visit other sights like Wyndham Plaza or Cross Creek Plantation Golf.