Find hotels in Isle of Palms South, Jacksonville

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Isle of Palms South hotels

Ponte Vedra Inn & Club

Ponte Vedra Inn & Club
5.0 star property
6.1 km from Isle of Palms South
9.4 out of 10, Exceptional, (815 reviews)
"Amazing. Loved it "
United States
Carol
The price is ₩726,422
₩852,450 total
includes taxes & fees
Feb 9 - Feb 10
Ponte Vedra Inn & Club

The Hotel Palms

The Hotel Palms
3.5 star property
6.6 km from Isle of Palms South
9.6 out of 10, Exceptional, (293 reviews)
"stayed here for an event and it was awesome"
United States
clayton
The price is ₩247,607
₩281,041 total
includes taxes & fees
Jan 25 - Jan 26
The Hotel Palms

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
4.8 km from Isle of Palms South
9.0 out of 10, Wonderful, (3,535 reviews)
"Friendly staff, clean rooms and great atmosphere!"
United States
Susan
The price is ₩196,474
₩222,998 total
includes taxes & fees
Jan 25 - Jan 26
Margaritaville Jacksonville Beach

Seahorse Oceanfront Inn

Seahorse Oceanfront Inn
2.5 star property
6.8 km from Isle of Palms South
8.8 out of 10, Excellent, (629 reviews)
"Great hotel "
United States
Jameida
Seahorse Oceanfront Inn

Salt Air Inn & Suites

Salt Air Inn & Suites
2.5 star property
6.6 km from Isle of Palms South
9.8 out of 10, Exceptional, (422 reviews)
"Amazing hotel absolute gem for Jacksonville beach "
United States
Justin
Salt Air Inn & Suites

Casa Marina Hotel

Casa Marina Hotel
3.0 star property
4.8 km from Isle of Palms South
8.4 out of 10, Very Good, (1,003 reviews)
"Room and hotel was very clean. Great old hotel with charm! Loved the roof top bar, views amazing. Location is perfect! "
Canada
Wayne
Casa Marina Hotel

One Ocean Resort and Spa

One Ocean Resort and Spa
4.5 star property
6.8 km from Isle of Palms South
8.8 out of 10, Excellent, (1,003 reviews)
"Clean rooms and very nice staff "
United States
Arthur
The price is ₩235,084
₩314,070 total
includes taxes & fees
Feb 9 - Feb 10
One Ocean Resort and Spa

Courtyard by Marriott Jacksonville Beach Oceanfront

Courtyard by Marriott Jacksonville Beach Oceanfront
3.0 star property
5.2 km from Isle of Palms South
8.4 out of 10, Very Good, (1,002 reviews)
"Good services and clean room. "
United States
Dan
The price is ₩247,607
₩281,034 total
includes taxes & fees
Jan 29 - Jan 30
Courtyard by Marriott Jacksonville Beach Oceanfront

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
3.8 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,020 reviews)
"Clean room, good breakfast and location"
United States
Jesus
The price is ₩179,010
₩203,175 total
includes taxes & fees
Feb 1 - Feb 2
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront
4.0 star property
4.7 km from Isle of Palms South
9.0 out of 10, Wonderful, (630 reviews)
"The hotel was great! Very clean room and staff were very courteous and professional"
United States
Mike
The price is ₩260,793
₩296,000 total
includes taxes & fees
Jan 29 - Jan 30
Springhill Suites By Marriott Jacksonville Beach Oceanfront

Four Points by Sheraton Jacksonville Beachfront

Four Points by Sheraton Jacksonville Beachfront
3.0 star property
4.5 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,001 reviews)
"Beds very comfortable. Check-in seamless. I loved my stay."
United States
Pizza
The price is ₩285,700
₩324,269 total
includes taxes & fees
Feb 8 - Feb 9
Four Points by Sheraton Jacksonville Beachfront

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.8 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,011 reviews)
"Staff was friendly and efficiently. Great location "
United States
Susan
The price is ₩206,905
₩230,699 total
includes taxes & fees
Feb 4 - Feb 5
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Fairfield Inn & Suites by Marriott Jacksonville Beach

Fairfield Inn & Suites by Marriott Jacksonville Beach
2.5 star property
5.2 km from Isle of Palms South
8.6 out of 10, Excellent, (896 reviews)
"Spacious clean rooms Good breakfast options Friendly staff Close to beach; fantastic location Newly renovated hotel property Paid parking but felt safe "
United States
Krunal
The price is ₩167,025
₩189,572 total
includes taxes & fees
Jan 28 - Jan 29
Fairfield Inn & Suites by Marriott Jacksonville Beach

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
1.9 km from Isle of Palms South
9.4 out of 10, Exceptional, (122 reviews)
"Great place to stay"
United States
Judy
The price is ₩263,108
₩298,627 total
includes taxes & fees
Feb 19 - Feb 20
Hilton Jacksonville At Mayo Clinic

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
9.5 km from Isle of Palms South
9.2 out of 10, Wonderful, (1,001 reviews)
"very friendly staff!! i love staying here!!"
United States
Evani
The price is ₩197,793
₩224,495 total
includes taxes & fees
Jan 25 - Jan 26
Hyatt Place Jacksonville / St. Johns Town Center

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
4.6 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,007 reviews)
"Great location, breakfast was delicious "
United States
Paul
The price is ₩184,592
₩209,512 total
includes taxes & fees
Jan 25 - Jan 26
Best Western Oceanfront

Hotel Indigo Jacksonville-Deerwood Park by IHG

Hotel Indigo Jacksonville-Deerwood Park by IHG
3.5 star property
11.6 km from Isle of Palms South
9.2 out of 10, Wonderful, (1,001 reviews)
"Great stay!"
United States
Margueritte
The price is ₩191,932
₩217,844 total
includes taxes & fees
Jan 29 - Jan 30
Hotel Indigo Jacksonville-Deerwood Park by IHG

Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
3.5 km from Isle of Palms South
9.2 out of 10, Wonderful, (1,001 reviews)
"Great for the quick stay! "
United States
Aaron
The price is ₩174,734
₩198,322 total
includes taxes & fees
Feb 4 - Feb 5
Holiday Inn Express Jacksonville Beach by IHG

Tru By Hilton Jacksonville St Johns Town Center

Tru By Hilton Jacksonville St Johns Town Center
2.5 star property
9.5 km from Isle of Palms South
9.0 out of 10, Wonderful, (849 reviews)
"Excellent hotel, very clean and inviting!"
United States
Stacie
The price is ₩173,882
₩197,357 total
includes taxes & fees
Feb 1 - Feb 2
Tru By Hilton Jacksonville St Johns Town Center

TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East
3.0 star property
2.9 km from Isle of Palms South
9.2 out of 10, Wonderful, (567 reviews)
"Very good hotel"
United States
Careli
The price is ₩167,025
₩189,574 total
includes taxes & fees
Feb 1 - Feb 2
TownePlace Suites by Marriott Jacksonville East
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Isle of Palms South

Find the best Isle of Palms South areas and neighborhoods for the activities you enjoy most.

Downtown Jacksonville

Historic core with major corporations, Downtown Jacksonville offers diverse culinary and nightlife experiences at The Elbow. Explore attractions like Florida Theatre, TIAA Bank Field, and museums, while enjoying convenient transportation options.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Sawgrass

Visitors to Sawgrass like its beaches and riverfront, and Mickler Beach is a sight worth a stop.

Southside

If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

American Beach

If you're spending some time in American Beach, American Beach and Spanish Quarter Village are top sights worth seeing.

Top Isle of Palms South Hotel Reviews

Frequently asked questions

What is Isle of Palms South like?
Travelers will be sure to find plenty to entertain them in Jacksonville Beach's Isle of Palms South neighborhood.
How many hotels will I be able to find in Isle of Palms South?
Expedia has 9 Isle of Palms South hotels and other accommodations, and one might make a good home base for venturing out into the greater Jacksonville Beach area.
If I need to cancel my hotel reservation in Isle of Palms South, will I receive a refund?
Yes, the majority of hotel room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then use the "fully refundable" filter to view top deals in Isle of Palms South.
Where can I learn more about changing or cancelling my trip to Isle of Palms South?
To find more details about changing or cancelling your trip to Isle of Palms South, go to https://www.expedia.com/service/.
What are the top things to see and do in Isle of Palms South?
Adventure Landing, Cradle Creek Preserve, and Windsor Parke Golf Club are just a few of the places to visit in and around Isle of Palms South. Jacksonville Beach Golf Club and Windsor Commons Shopping Center are also worth a visit when you're out sightseeing in Jacksonville Beach.