Find hotels near Mayo Clinic Florida, Jacksonville from ₩188,461

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Mar 31 - Apr 1
Tomorrow
Apr 1 - Apr 2
This weekend
Apr 3 - Apr 5
Next weekend
Apr 10 - Apr 12

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mayo Clinic Florida hotels

Lobby lounge

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
1.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (480 reviews)
"Great stay! Clean room, friendly staff. "
United States
Sabrena
The price is ₩240,273
₩272,709 total
includes taxes & fees
Apr 19 - Apr 20
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Breakfast, lunch, dinner served; American cuisine

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
0.8 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (189 reviews)
"Great place to stay"
United States
Judy
The price is ₩281,769
₩319,809 total
includes taxes & fees
Apr 19 - Apr 20
Hilton Jacksonville At Mayo Clinic
Terrace/patio

TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East
3.0 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (598 reviews)
"Very nice accommodation , clean , and comfortable"
United States
Kevin
The price is ₩179,827
₩204,104 total
includes taxes & fees
Apr 27 - Apr 28
TownePlace Suites by Marriott Jacksonville East
Lobby

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,003 reviews)
"Nice room nice stay friendly staff"
United States
Thomas
The price is ₩166,045
₩188,461 total
includes taxes & fees
Apr 19 - Apr 20
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Lobby sitting area

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
2.6 km from Mayo Clinic Florida
8.8 out of 10, Excellent, (1,006 reviews)
"Great stay!"
United States
Satavia
The price is ₩170,006
₩192,957 total
includes taxes & fees
Apr 12 - Apr 13
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Terrace/patio

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
0.4 km from Mayo Clinic Florida
8.4 out of 10, Very Good, (768 reviews)
"Room very clear; staff friendly and helpful; safe parking with accessibility to Mayo Clinic "
United States
Nancy
The price is ₩243,295
₩276,139 total
includes taxes & fees
Apr 18 - Apr 19
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
Free daily buffet breakfast

Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
4.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,006 reviews)
"Great hotel, very friendly, free breakfast! "
United States
Daniel
The price is ₩188,894
₩214,395 total
includes taxes & fees
Apr 19 - Apr 20
Holiday Inn Express Jacksonville Beach by IHG
BBQ/picnic area

The Hotel Palms Poolside

The Hotel Palms Poolside
2.5 star property
7.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (457 reviews)
"The room was clean, staff was friendly and helpful, and location was great. "
United States
Rocky
The price is ₩272,904
₩309,747 total
includes taxes & fees
Apr 6 - Apr 7
The Hotel Palms Poolside
Property amenity

Element Jacksonville Beach

Element Jacksonville Beach
3.0 star property
5.4 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (543 reviews)
"Rooms were clean. Proximity to beach was optimal. Daily made to order breakfast was simply amazing. "
United States
Sean M
The price is ₩294,674
₩334,456 total
includes taxes & fees
Apr 20 - Apr 21
Element Jacksonville Beach
Lobby

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
5.9 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (3,809 reviews)
"beautiful hotel, good location"
United States
Robert E.
The price is ₩258,196
₩293,062 total
includes taxes & fees
Apr 5 - Apr 6
Margaritaville Jacksonville Beach
Standard Room, 1 King Bed, Non Smoking | Down comforters, minibar, iron/ironing board, WiFi

The Hotel Palms Courtyard

The Hotel Palms Courtyard
3.5 star property
7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (294 reviews)
"stayed here for an event and it was awesome"
United States
clayton
The price is ₩303,315
₩344,263 total
includes taxes & fees
Apr 7 - Apr 8
The Hotel Palms Courtyard
2 outdoor pools, open 7:00 AM to 9:00 PM, pool umbrellas, sun loungers

Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront
3.0 star property
6.3 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (2,656 reviews)
"Great place!"
United States
Kathleen
The price is ₩297,480
₩337,639 total
includes taxes & fees
Apr 22 - Apr 23
Hampton Inn Jacksonville Beach/Oceanfront
Sports facility

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
Southside, 8.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,002 reviews)
"Great place to stay at!"
United States
R.
The price is ₩203,400
₩230,859 total
includes taxes & fees
Apr 5 - Apr 6
Hyatt Place Jacksonville / St. Johns Town Center
On the beach

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
5.7 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,008 reviews)
"Good location, helpful staff, comfortable room with a great Oceanview balcony."
United States
Robert
The price is ₩242,850
₩275,637 total
includes taxes & fees
Apr 13 - Apr 14
Best Western Oceanfront
Lounge

AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center
2.5 star property
Southside, 8.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (185 reviews)
"Staff was excellent...highly recommend this Hotel"
Canada
Robert
The price is ₩270,496
₩307,020 total
includes taxes & fees
Apr 3 - Apr 4
AC Hotel Jacksonville St Johns Town Center
Snack bar

Tru By Hilton Jacksonville St Johns Town Center

Tru By Hilton Jacksonville St Johns Town Center
2.5 star property
Southside, 8.7 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (877 reviews)
"Clean room, professional staff, & good breakfast bar"
United States
Dwight
The price is ₩185,610
₩210,667 total
includes taxes & fees
Apr 5 - Apr 6
Tru By Hilton Jacksonville St Johns Town Center
Exterior

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG
2.5 star property
Southside, 7.7 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (1,005 reviews)
"Great location, friendly staff, nice rooms, great breakfast."
United States
Michelle
The price is ₩185,185
₩210,185 total
includes taxes & fees
Apr 20 - Apr 21
Holiday Inn Express & Suites Jacksonville - Town Center by IHG
Outdoor pool, pool umbrellas, sun loungers

Four Points by Sheraton Jacksonville Beachfront

Four Points by Sheraton Jacksonville Beachfront
3.0 star property
5.6 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,002 reviews)
"Good room"
United States
Michael
The price is ₩347,601
₩394,526 total
includes taxes & fees
Apr 12 - Apr 13
Four Points by Sheraton Jacksonville Beachfront
Bar (on property)

Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront
4.0 star property
5.8 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (657 reviews)
"Good clean rooms and property "
United States
Michael
The price is ₩288,630
₩327,595 total
includes taxes & fees
Apr 20 - Apr 21
Springhill Suites By Marriott Jacksonville Beach Oceanfront
Lobby

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.5 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,004 reviews)
"Great stay all around "
United States
Jeffrey
The price is ₩271,584
₩302,816 total
includes taxes & fees
Apr 19 - Apr 20
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Mayo Clinic Florida

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Lobby lounge
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
9.4
Exceptional
480 reviews
View
Breakfast, lunch, dinner served; American cuisine
Hilton Jacksonville At Mayo Clinic
4.5 star property
9.4
Exceptional
189 reviews
View
Terrace/patio
TownePlace Suites by Marriott Jacksonville East
3.0 star property
9.2
Wonderful
598 reviews
View
Lobby
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
9.0
Wonderful
1,003 reviews
View
Lobby sitting area
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
8.8
Excellent
1,006 reviews
View

Top Mayo Clinic Florida Hotel Reviews

Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront

2/10 Terrible
"This hotel is run down and not taken care of. The pool is tiny and the hotel is noisy. There is no sound barrier between rooms. Way over priced. This hotel was so disgusting we checked the same day we checked in. Not recommended. "
Melissa 2-night trip
Posted 2 hours ago
Hampton Inn Jacksonville Beach/Oceanfront

Hotels near other Mayo Clinic Florida attractions

Windsor Parke Golf Club

Enjoy a round of golf in Jacksonville at Windsor Parke Golf Club. Amble around the area's beautiful beaches or attend a sporting event.
See properties

Windsor Commons Shopping Center

You can enjoy retail therapy at Windsor Commons Shopping Center during your trip to Jacksonville. Experience the area's acclaimed theater scene and great live music.
See properties

Frequently asked questions

What's the area like around Mayo Clinic Florida?
Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, check out the 49 hotels and other accommodations you'll find within a mile.
What's the best place to stay close to Mayo Clinic Florida?
Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices close by include Hilton Jacksonville At Mayo Clinic and Residence Inn By Marriott Jacksonville - Mayo Clinic Area.
How many hotels will I find near Mayo Clinic Florida?
Expedia has 49 hotels and other accommodations within a mile from Mayo Clinic Florida.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best deals available near Mayo Clinic Florida.
Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Florida?
To access more information about picking new dates or cancelling your stay near Mayo Clinic Florida, head over to our customer service page.
What can I see and do near Mayo Clinic Florida?
You can catch a show at SeaWalk Pavillion, SeaWalk Pavillion, and Players by the Sea. Spend some time exploring the natural beauty of Huguenot Park, Oceanfront Park, and Gonzales Park. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.