Find hotels near Mayo Clinic Florida, Jacksonville from ₩173,792

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Nov 14 - Nov 15
Tomorrow
Nov 15 - Nov 16
This weekend
Nov 14 - Nov 16
Next weekend
Nov 21 - Nov 23

Filter by

Guest rating
Guest rating
Star rating

Compare 1,849 hotels close to Mayo Clinic Florida with room rates, reviews, and availability. Most hotels are fully refundable.

Breakfast, lunch, dinner served; American cuisine
Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic

4.5 star property
0.8 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (21)
"Clean, comfortable, nice restaurant & coffee shop. "
United States
Joahnna
The price is ₩179,712
₩203,973 total
includes taxes & fees
Nov 23 - Nov 24
Hilton Jacksonville At Mayo Clinic
Reception
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3.0 star property
1.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (437)
"All was good "
United States
Jacob
The price is ₩232,399
₩263,773 total
includes taxes & fees
Nov 21 - Nov 22
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Terrace/patio
TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East

3.0 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (539)
"Very good hotel"
United States
Careli
The price is ₩167,441
₩190,046 total
includes taxes & fees
Dec 15 - Dec 16
TownePlace Suites by Marriott Jacksonville East
Terrace/patio
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

2.5 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1001)
"Enjoyed my stay"
United States
joseph
The price is ₩157,678
₩178,964 total
includes taxes & fees
Nov 23 - Nov 24
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Lobby sitting area
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

2.5 star property
2.7 km from Mayo Clinic Florida
8.6 out of 10, Excellent, (1000)
"We enjoyed the stay."
United States
Kenny
The price is ₩160,326
₩181,971 total
includes taxes & fees
Nov 29 - Nov 30
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Terrace/patio
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

3.0 star property
0.3 km from Mayo Clinic Florida
8.4 out of 10, Very Good, (749)
"Nice hotel, close to shops and mayo clinic."
United States
Judy
The price is ₩236,812
₩268,782 total
includes taxes & fees
Nov 22 - Nov 23
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
Lobby
Element Jacksonville Beach

Element Jacksonville Beach

3.0 star property
5.4 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (510)
"Excellent "
United States
Amarbayar
The price is ₩198,569
₩225,375 total
includes taxes & fees
Nov 23 - Nov 24
Element Jacksonville Beach
BBQ/picnic area
Salt Air Inn & Suites

Salt Air Inn & Suites

2.5 star property
7.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (395)
"A cute little gem with some of the best hospitality in the area. "
United States
Windy
The price is ₩206,804
₩234,726 total
includes taxes & fees
Nov 25 - Nov 26
Salt Air Inn & Suites
Exterior
Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

2.5 star property
Southside, 7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (1004)
"Always enjoy staying here when we come down from Va"
United States
Tammy
The price is ₩188,273
₩213,690 total
includes taxes & fees
Nov 23 - Nov 24
Holiday Inn Express & Suites Jacksonville - Town Center by IHG
Property amenity
TownePlace Suites by Marriott® Jacksonville Mayport

TownePlace Suites by Marriott® Jacksonville Mayport

3.0 star property
10.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (49)
"This was an awesome place to stay."
United States
Christine
The price is ₩170,622
₩193,655 total
includes taxes & fees
Dec 12 - Dec 13
TownePlace Suites by Marriott® Jacksonville Mayport
Standard Room, 2 Queen Beds, Non Smoking | 1 bedroom, down comforters, minibar, iron/ironing board
The Hotel Palms

The Hotel Palms

3.5 star property
7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (291)
"stayed here for an event and it was awesome"
United States
clayton
The price is ₩277,599
₩315,082 total
includes taxes & fees
Dec 1 - Dec 2
The Hotel Palms
On the beach, white sand, surfing, kayaking
Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

2.5 star property
5.9 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (3346)
"I had a great weekend stay on my birthday! "
United States
Adrian
Margaritaville Jacksonville Beach
2 outdoor pools, open 7:00 AM to 9:00 PM, pool umbrellas, sun loungers
Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront

3.0 star property
6.3 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (2552)
"Very nice oceanfront hotel with a friendly staff and really good breakfast."
United States
Kawanda
The price is ₩174,152
₩197,663 total
includes taxes & fees
Nov 23 - Nov 24
Hampton Inn Jacksonville Beach/Oceanfront
Reception
Ponte Vedra Inn & Club

Ponte Vedra Inn & Club

5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (811)
"All good "
United Kingdom
Randall
The price is ₩586,043
₩696,033 total
includes taxes & fees
Nov 30 - Dec 1
Ponte Vedra Inn & Club
Sports facility
Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center

3.0 star property
Southside, 8.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1001)
"Always a great place to stay!"
United States
Richard
The price is ₩197,098
₩223,706 total
includes taxes & fees
Nov 25 - Nov 26
Hyatt Place Jacksonville / St. Johns Town Center
Beach/ocean view
The Lodge and Club at Ponte Vedra Beach

The Lodge and Club at Ponte Vedra Beach

5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (684)
"Clean room, excellent service and only steps from the ocean. The facility could use some TLC but, all in all, a wonderful place to stay. We’ll be back for sure. "
United States
Robert
The price is ₩586,043
₩696,033 total
includes taxes & fees
Nov 23 - Nov 24
The Lodge and Club at Ponte Vedra Beach
On the beach
Best Western Oceanfront

Best Western Oceanfront

3.0 star property
5.7 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1003)
"staff at front desk was professional and accomadating "
United States
Robert
The price is ₩181,198
₩205,660 total
includes taxes & fees
Nov 23 - Nov 24
Best Western Oceanfront
Property amenity
Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel

4.0 star property
Deerwood, 9.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1001)
"Great stay and great customer service"
United States
Rebecca
The price is ₩153,120
₩173,792 total
includes taxes & fees
Nov 27 - Nov 28
Sheraton Jacksonville Hotel
Free daily buffet breakfast
Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG

3.0 star property
4.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1001)
"Everything was top notch "
United States
Ginger
The price is ₩163,268
₩185,309 total
includes taxes & fees
Nov 24 - Nov 25
Holiday Inn Express Jacksonville Beach by IHG
On the beach, windsurfing
Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront

4.0 star property
5.8 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (614)
"Everything was perfect! "
United States
Lindsey
The price is ₩223,574
₩253,757 total
includes taxes & fees
Nov 24 - Nov 25
Springhill Suites By Marriott Jacksonville Beach Oceanfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Mayo Clinic Florida Hotel Reviews

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic

10/10 Excellent
"Gorgeous brand new hotel. "
Christine 2-night trip
Posted 2 days ago
Hilton Jacksonville At Mayo Clinic

Hotels near other Mayo Clinic Florida attractions

Adventure Landing

4.1/5 (157 reviews)
This amusement park east of Jacksonville is a fun daytrip for the whole family with thrilling rides, exciting attractions for kids and a shipwreck-themed waterpark.
See properties

Windsor Parke Golf Club

Enjoy a round of golf in Jacksonville at Windsor Parke Golf Club. Amble around the area's beautiful beaches or attend a sporting event.
See properties

Frequently asked questions

What's the area like around Mayo Clinic Florida?
Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, check out the 42 hotels and other accommodations you'll find within a mile.
What's the best place to stay close to Mayo Clinic Florida?
Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices close by include Hilton Jacksonville At Mayo Clinic and Residence Inn By Marriott Jacksonville - Mayo Clinic Area.
How many hotels will I find near Mayo Clinic Florida?
Expedia has 42 hotels and other accommodations within a mile from Mayo Clinic Florida.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best deals available near Mayo Clinic Florida.
Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Florida?
To access more information about picking new dates or cancelling your stay near Mayo Clinic Florida, head over to our customer service page.
What can I see and do near Mayo Clinic Florida?
You can enjoy live performances at Wilson Center For the Arts and Players by the Sea. Spend some time exploring the natural beauty of Huguenot Park, Oceanfront Park, and Gonzales Park. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.

Explore a world of travel with Expedia