The Best Hotels Closest to Louisville Science Center in Louisville for 2026

The entrance to the Kentucky Science Center with a large circular structure in the foreground.

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Our top choices for Louisville Science Center hotels

A grand staircase with a wooden handrail and carpeted steps, leading to an upper floor.

A living room with a sofa, armchair, coffee table, fireplace, and large windows.

A building entrance with a dark door, a large number '1332' above it, and two large potted ferns on either side.

A covered outdoor seating area with wicker furniture and a wooden railing.

1. Louisville Bourbon Inn

Old Louisville, 2.9 km from Louisville Science Center

Roy

₩369,142

₩428,462 total

includes taxes & fees

Oct 26 - Oct 27

A wooden staircase with a balustrade leading to a landing.

A two-story brick building with a white porch and a sign reading "Hotel".

A dining area with brick walls, wooden shelves, and tables set for a meal.

A brick building with a covered porch, columns, and potted plants.

2. Market Street Inn

2.1 km from Louisville Science Center

Holly

₩292,575

₩330,614 total

includes taxes & fees

Oct 26 - Oct 27

An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.

A modern living room with a leather sectional sofa, a glass coffee table, and a view of the city skyline through large windows.

A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.

An outdoor dining area with tables and chairs, a green building facade, and a row of plants along the wall.

3. Hotel Distil, Autograph Collection

Downtown Louisville, 0.9 km from Louisville Science Center

Heather

₩266,629

₩313,716 total

includes taxes & fees

Nov 22 - Nov 23

A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.

A room with a large mirror, a wooden dresser, a red patterned rug, and a door with a wreath.

A room with a red velvet sofa, a blue armchair, and a small round table with books.

An outdoor patio with red furniture, including a table and chairs, and two red umbrellas providing shade.

4. DuPont Mansion Bed & Breakfast

Old Louisville, 2.8 km from Louisville Science Center

Casey

₩188,977

₩219,346 total

includes taxes & fees

Nov 1 - Nov 2

A grand lobby with ornate columns, plush seating, and a chandelier.

A grand lobby with ornate ceiling, multiple seating areas, and a staircase.

A grand lobby with ornate ceiling and chandeliers, a large vase, and a seating area with multiple sofas and armchairs.

A grand dining area with ornate ceiling, chandeliers, and a bar area with a sign reading "Cigar Bar".

5. The Brown Hotel

Downtown Louisville, 1.2 km from Louisville Science Center

katisha

₩178,882

₩210,464 total

includes taxes & fees

Nov 23 - Nov 24

A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.

A spacious hotel lobby with a central seating area, stone accent walls, and a chandelier.

A spacious lobby with a large seating area, a chandelier, and a patterned rug.

A modern hotel with multiple floors, large windows, and a prominent sign for Homewood Suites.

6. Homewood Suites by Hilton Louisville Downtown, KY

Downtown Louisville, 0.2 km from Louisville Science Center

peter

₩150,806

₩177,439 total

includes taxes & fees

Nov 24 - Nov 25

A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

A multi-level interior with a staircase, bookshelves, and a prominent sign reading "THE GRADY".

A modern hotel room with a large bed, a desk with a flat-screen TV, a green armchair, and a view of the city through large windows.

A modern restaurant interior with a staircase, round tables, and a brick wall.

7. The Grady

Downtown Louisville, 0.2 km from Louisville Science Center

Donna

₩206,065

₩242,456 total

includes taxes & fees

Nov 15 - Nov 16

A classical gold statue in front of a multi-story building with large windows and a brick facade.

A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.

A cozy room with a geometric-patterned ceiling, a sofa, and a chair.

8. 21c Museum Hotel Louisville

Downtown Louisville, < 0.1 km from Louisville Science Center

Matt

₩201,295

₩243,459 total

includes taxes & fees

Nov 22 - Nov 23

A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.

A lobby with a marble floor, a reception desk, and a large chandelier.

A modern interior with a fireplace, bookshelves, and seating areas.

9. Omni Louisville Hotel

Downtown Louisville, 0.8 km from Louisville Science Center

Kristan

₩268,852

₩316,331 total

includes taxes & fees

Nov 16 - Nov 17

An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.

A modern hotel room with a large bed, a desk with a chair, a flat-screen TV, and a large window offering a city view.

A modern restaurant with high tables and booths, wooden ceiling panels, and framed pictures on the walls.

A modern hotel lobby with a brick wall, grey sofas, a coffee table, and a large TV screen displaying "TEMPO by Hilton".

10. Tempo By Hilton Louisville Downtown Nulu

Phoenix Hill, 2.1 km from Louisville Science Center

Addison

₩136,702

₩160,843 total

includes taxes & fees

Nov 25 - Nov 26

A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.

A modern bedroom with a bed, a blue sofa, a large rug, and a TV on the wall.

A modern interior with a green wall, black chairs, and a ceiling with exposed beams and lights.

A modern KFC building with large glass windows, a prominent sign, and a well-lit entrance area.

11. Stellar Suites

East Market District, 2.2 km from Louisville Science Center

Kevin

₩153,008

₩246,703 total

includes taxes & fees

Oct 27 - Oct 28

An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.

A modern hotel room with a large bed, a city view, and a unique headboard design.

A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.

A modern living room with a sofa, a coffee table, a side table with a plant, and a view of a building with a clock tower.

12. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Downtown Louisville, 0.8 km from Louisville Science Center

Adrienne Tremonti

₩172,504

₩202,967 total

includes taxes & fees

Nov 23 - Nov 24

An outdoor seating area with wicker furniture and a fire pit.

An indoor swimming pool with clear water, a diving board, and lounge chairs around the pool area.

A modern living room with a sofa, armchairs, a coffee table, and a TV.

A modern lounge area with seating, tables, and a view of the city through large windows.

13. Towneplace Suites By Marriott Louisville Downtown

Downtown Louisville, 0.3 km from Louisville Science Center

Barbara

₩138,924

₩163,458 total

includes taxes & fees

Nov 8 - Nov 9

A modern bar area with a circular bar, multiple seating options, and a large screen.

A spacious indoor area with a large dining table, multiple chairs, a fireplace, and a kitchen area with a bar.

A modern living room with a sectional sofa, a small table, and a floor lamp. Large windows offer a view of a cityscape and a building with glass windows.

A modern interior with a central wooden table, refrigerated beverage dispensers, and shelves stocked with snacks and condiments.

14. Cambria Hotel Louisville Downtown-Whiskey Row

Downtown Louisville, 1.2 km from Louisville Science Center

Sarah

₩125,958

₩148,202 total

includes taxes & fees

Nov 22 - Nov 23

An indoor dining area with wooden tables and chairs, a bar area, and a view of the street outside.

A modern coffee shop interior with a central island, wooden counter, and large windows.

A modern lounge area with a pool table, comfortable seating, a fireplace, and a brick accent wall.

A modern bar area with sofas, tables, and a bar stocked with bottles.

15. Aloft by Marriott Louisville Downtown

Downtown Louisville, 0.9 km from Louisville Science Center

Anthony

₩161,840

₩190,420 total

includes taxes & fees

Nov 23 - Nov 24

A bar area with a neon 'CHECK IN' sign, a variety of liquor bottles, and a modern seating arrangement.

A cozy living room with a fireplace, a black leather sofa, and a patterned rug.

A modern hotel with a prominent 'Marriott' sign, large windows, and a brick facade.

A modern hotel room with a large bed, a desk with a chair, a TV mounted on the wall, and a window with a city view.

16. Moxy Louisville Downtown

Downtown Louisville, 0.9 km from Louisville Science Center

Alicia

₩156,324

₩183,930 total

includes taxes & fees

Nov 15 - Nov 16

A restaurant with a long counter, multiple tables, and chairs. There are large windows with a view of the city.

A bedroom with a bed, a chair, a TV, and a window with curtains.

A room with a checkered floor, leather armchairs, a sofa, and a small table with a glass. There are windows with arched tops and a view of buildings outside.

A bar area with a wooden bar counter, two stools, a chandelier, and a mirror.

17. Hotel Genevieve part of JdV by Hyatt

East Market District, 2.1 km from Louisville Science Center

Tyler

₩178,617

₩210,161 total

includes taxes & fees

Oct 31 - Nov 1

A modern bar area with a marble countertop, seating, and a central bar stocked with bottles.

A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.

A modern interior with a central seating area, a television screen, and a wooden partition with various items displayed.

A modern restaurant with high ceilings, large windows, and a mix of round and rectangular tables.

18. AC Hotel Louisville Downtown

East Market District, 2.1 km from Louisville Science Center

Jen

₩189,334

₩222,772 total

includes taxes & fees

Nov 6 - Nov 7

A covered patio with a stone wall, a glass table, and a bench.

A stone house with a balcony, a front door, and a staircase leading to the entrance.

A garden pathway with a lantern, potted plants, and a white fence.

19. Central Park Bed & Breakfast

Old Louisville, 3 km from Louisville Science Center

Nicole

₩225,944

₩262,263 total

includes taxes & fees

Oct 26 - Oct 27

A modern interior with large windows offering a city view, a circular light fixture, and leather seating.

A spacious room with a large dining table, comfortable seating, a sofa, and a view of a bridge.

A modern bar with a long counter, multiple shelves of liquor bottles, and cushioned bar stools.

A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.

20. Galt House Hotel Trademark Collection by Wyndham

Downtown Louisville, 0.5 km from Louisville Science Center

Shun

₩180,099

₩211,904 total

includes taxes & fees

Nov 8 - Nov 9

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Compare top hotels near Louisville Science Center

Louisville Bourbon Inn Old Louisville, 2.9 km from Louisville Science Center View	Market Street Inn 2.1 km from Louisville Science Center View	Hotel Distil, Autograph Collection Downtown Louisville, 0.9 km from Louisville Science Center View	DuPont Mansion Bed & Breakfast Old Louisville, 2.8 km from Louisville Science Center View	The Brown Hotel Downtown Louisville, 1.2 km from Louisville Science Center View
10.0 Exceptional 25 reviews	9.8 Exceptional 126 reviews	9.6 Exceptional 512 reviews	9.6 Exceptional 150 reviews	9.4 Exceptional 1,421 reviews
₩369,142 ₩428,462 total includes taxes & fees Oct 26 - Oct 27	₩292,575 ₩330,614 total includes taxes & fees Oct 26 - Oct 27	₩266,629 ₩313,716 total includes taxes & fees Nov 22 - Nov 23	₩188,977 ₩219,346 total includes taxes & fees Nov 1 - Nov 2	₩178,882 ₩210,464 total includes taxes & fees Nov 23 - Nov 24

Top Louisville Science Center Hotel Reviews

The Grady

8/10 Good

"Room was too ch old and hard to control comfortable temp"

Towneplace Suites By Marriott Louisville Downtown

10/10 Excellent

"10/10 From check in to check out. I loved the room, the hotel was spotless and staff were wonderful. I would recommend again and I will definitely stay there again when I’m back in town."

Holiday Inn Louisville Downtown by IHG

8/10 Good

"Convince, close to the Convention Center"

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

10/10 Excellent

"Great location for whiskey row! Everyone was so and we wish we’d have had another night!! Highly recommend!"

Fairfield Inn & Suites by Marriott Louisville Downtown

10/10 Excellent

"Great Location"

Homewood Suites by Hilton Louisville Downtown, KY

10/10 Excellent

"Yes. They were very helpful and it was a great stay!"

Other attractions near Louisville Science Center

A tall wooden baseball bat leaning against a brick building with a sign reading "Hillerich & Brassler Co."

Louisville Slugger Museum

9.2/10 (2,299 reviews)

Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.

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A modern building with a cylindrical structure and a glass facade.

Muhammad Ali Center

8.8/10 (295 reviews)

One of the world’s greatest boxers continues providing inspiration beyond the world of sport. Understand this superstar by visiting this center honoring him.

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The Frazier History Museum with red doors and a tree in front.

Frazier International History Museum

9.4/10 (10 reviews)

Get to know Louisville with a visit to this esteemed museum. It’s a great spot for social interaction as well.

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Kentucky Center for the Performing Arts

8.8/10 (49 reviews)

Enjoy a pleasant night at the opera or attend a concert, live dance or stage production at this glass-fronted venue in downtown Louisville.

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Kentucky Museum of Art and Craft

You can spend an afternoon exploring the galleries in Kentucky Museum of Art and Craft during your travels in Louisville. Stroll along the area's riverfront or experience its lively festivals.

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Golden Statue of David

Find out about the history of Louisville when you take a trip to Golden Statue of David. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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SAR Genealogical Research Library: NSSAR Library

You can spend an afternoon browsing the exhibits at SAR Genealogical Research Library: NSSAR Library in Louisville. Amble around this family-friendly area's riverfront and enjoy its top-notch restaurants.

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Louisville Glassworks

You can spend an afternoon studying the exhibits at Louisville Glassworks in Louisville. Experience the area's lively festivals or attend a sporting event.

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Frequently asked questions

What's the area like around Louisville Science Center?

Louisville Science Center is located in an area of Louisville known for its beautiful river views, sporting events, and great live music scene. If you're looking for a convenient place to stay, check out the 292 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Louisville Science Center?

Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a 24-hour fitness center. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.

How many hotels can I expect to find close to Louisville Science Center?

Expedia has 292 hotels and other accommodations within a mile from Louisville Science Center.

If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?

Yes, you'll find most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to review the best deals near Louisville Science Center.

Where can I learn more about changing or cancelling my trip in the area near Louisville Science Center?

For more details about picking new dates or cancelling your stay near Louisville Science Center, click here.

What can I see and do near Louisville Science Center?

21c Museum Hotel, Louisville Slugger Museum, and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row, and Big Four Bridge. You can catch a show at Louisville Palace, Derby Dinner Playhouse, and Headliners Music Hall.

Find hotels near Louisville Science Center, Louisville from ₩148,202

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Our top choices for Louisville Science Center hotels

1. Louisville Bourbon Inn

2. Market Street Inn

3. Hotel Distil, Autograph Collection

4. DuPont Mansion Bed & Breakfast

5. The Brown Hotel

6. Homewood Suites by Hilton Louisville Downtown, KY

7. The Grady

8. 21c Museum Hotel Louisville

9. Omni Louisville Hotel

10. Tempo By Hilton Louisville Downtown Nulu

11. Stellar Suites

12. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

13. Towneplace Suites By Marriott Louisville Downtown

14. Cambria Hotel Louisville Downtown-Whiskey Row

15. Aloft by Marriott Louisville Downtown

16. Moxy Louisville Downtown

17. Hotel Genevieve part of JdV by Hyatt

18. AC Hotel Louisville Downtown

19. Central Park Bed & Breakfast

20. Galt House Hotel Trademark Collection by Wyndham

Compare top hotels near Louisville Science Center

Louisville Bourbon Inn

Market Street Inn

Hotel Distil, Autograph Collection

DuPont Mansion Bed & Breakfast

The Brown Hotel

Top Louisville Science Center Hotel Reviews

The Grady

Towneplace Suites By Marriott Louisville Downtown

Holiday Inn Louisville Downtown by IHG

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Fairfield Inn & Suites by Marriott Louisville Downtown

Homewood Suites by Hilton Louisville Downtown, KY

Other attractions near Louisville Science Center

Louisville Slugger Museum

Muhammad Ali Center

Frazier International History Museum

Kentucky Center for the Performing Arts

Kentucky Museum of Art and Craft

Golden Statue of David

SAR Genealogical Research Library: NSSAR Library

Louisville Glassworks

Frequently asked questions