Find hotels in Medical Center Area, Boston

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Medical Center Area hotels

The Inn at Longwood Medical

The Inn at Longwood Medical
3.5 star property
Medical Center Area
8.4 out of 10, Very Good, (1,005 reviews)
"Everyone is so friendly and helpful. The rooms are clean and it is close to the medical facilities, as well as, easy access to downtown Boston. "
United States
Corinne
The price is ₩297,257
₩388,751 total
includes taxes & fees
Jan 30 - Jan 31
The Inn at Longwood Medical

Hilton Boston Park Plaza

Hilton Boston Park Plaza
4.0 star property
Bay Village, 3.1 km from Medical Center Area
8.4 out of 10, Very Good, (3,122 reviews)
"Clean and amenities were great"
United States
Lauryn
The price is ₩130,594
₩211,704 total
includes taxes & fees
Feb 22 - Feb 23
Hilton Boston Park Plaza

Copley Square Hotel, a FOUND Hotel

Copley Square Hotel, a FOUND Hotel
4.0 star property
Prudential - St. Botolph, 2.3 km from Medical Center Area
8.6 out of 10, Excellent, (3,925 reviews)
"Great location, clean and comfy room, friendly staff."
United States
Zachary
The price is ₩116,767
₩135,975 total
includes taxes & fees
Feb 8 - Feb 9
Copley Square Hotel, a FOUND Hotel

Hyatt Regency Boston

Hyatt Regency Boston
4.0 star property
Downtown Crossing, 3.9 km from Medical Center Area
9.0 out of 10, Wonderful, (1,820 reviews)
"Amazing place to stay! "
United States
Yohlman
The price is ₩190,806
₩273,407 total
includes taxes & fees
Feb 1 - Feb 2
Hyatt Regency Boston

Omni Boston Hotel at the Seaport

Omni Boston Hotel at the Seaport
5.0 star property
Seaport District, 5.1 km from Medical Center Area
9.2 out of 10, Wonderful, (4,447 reviews)
"Beautiful hotel!"
United States
Suzanne
The price is ₩178,808
₩267,861 total
includes taxes & fees
Feb 1 - Feb 2
Omni Boston Hotel at the Seaport

The Dagny Boston

The Dagny Boston
4.0 star property
Boston Financial District, 4.6 km from Medical Center Area
9.4 out of 10, Exceptional, (7,028 reviews)
"Beautiful hotel, great location, very friendly and helpful staff!"
United States
Jeffrey
The price is ₩185,319
₩266,909 total
includes taxes & fees
Jan 30 - Jan 31
The Dagny Boston

Aloft by Marriott, Boston Seaport District

Aloft by Marriott, Boston Seaport District
3.0 star property
Seaport District, 4.9 km from Medical Center Area
9.0 out of 10, Wonderful, (1,413 reviews)
"Nice hotel"
United States
Michael
The price is ₩168,273
₩238,549 total
includes taxes & fees
Feb 15 - Feb 16
Aloft by Marriott, Boston Seaport District

Hyatt Place Boston/Seaport District

Hyatt Place Boston/Seaport District
3.0 star property
Seaport District, 5.6 km from Medical Center Area
9.4 out of 10, Exceptional, (2,299 reviews)
"Absolutely spotless with great staff, comfortable beds, fun location"
United States
Sarah
The price is ₩197,830
₩230,372 total
includes taxes & fees
Jan 31 - Feb 1
Hyatt Place Boston/Seaport District

citizenM Boston North Station

citizenM Boston North Station
4.0 star property
West End, 4.6 km from Medical Center Area
9.4 out of 10, Exceptional, (4,307 reviews)
"Great location and great staff"
United States
Anthony
The price is ₩169,736
₩197,659 total
includes taxes & fees
Feb 1 - Feb 2
citizenM Boston North Station

The Godfrey Hotel Boston

The Godfrey Hotel Boston
4.0 star property
Downtown Crossing, 3.9 km from Medical Center Area
9.4 out of 10, Exceptional, (4,896 reviews)
"Nice hotel in great location"
United States
Eric
The price is ₩156,713
₩250,652 total
includes taxes & fees
Jan 29 - Jan 30
The Godfrey Hotel Boston

YOTEL Boston

YOTEL Boston
4.0 star property
4.9 km from Medical Center Area
8.6 out of 10, Excellent, (2,412 reviews)
"Great stay overall! "
United States
Lourdes
The price is ₩142,373
₩233,953 total
includes taxes & fees
Jan 30 - Jan 31
YOTEL Boston

The Westin Boston Seaport District

The Westin Boston Seaport District
4.0 star property
Seaport District, 5 km from Medical Center Area
9.2 out of 10, Wonderful, (2,391 reviews)
"Great staff, excellent room."
United States
Wayne
The price is ₩193,221
₩361,321 total
includes taxes & fees
Feb 16 - Feb 17
The Westin Boston Seaport District

Renaissance® Boston Seaport District

Renaissance® Boston Seaport District
4.0 star property
Seaport District, 5.4 km from Medical Center Area
9.0 out of 10, Wonderful, (1,003 reviews)
"Clean room, very kind staff at the restaurant. "
United States
lina
The price is ₩185,831
₩276,041 total
includes taxes & fees
Jan 31 - Feb 1
Renaissance® Boston Seaport District

Staypineapple, A Delightful Hotel, South End

Staypineapple, A Delightful Hotel, South End
3.0 star property
2.9 km from Medical Center Area
9.0 out of 10, Wonderful, (1,008 reviews)
"We've been to several Staypineapple hotels and they're always great. Clean rooms with comfortable beds and nice little extras that make the stay more pleasant."
Canada
Jan S
The price is ₩93,646
₩151,574 total
includes taxes & fees
Feb 8 - Feb 9
Staypineapple, A Delightful Hotel, South End

Seaport Hotel Boston

Seaport Hotel Boston
4.0 star property
Seaport District, 5.3 km from Medical Center Area
9.6 out of 10, Exceptional, (3,949 reviews)
"Great accommodations and friendly staff!"
United States
Nicholas
The price is ₩211,438
₩296,132 total
includes taxes & fees
Jan 31 - Feb 1
Seaport Hotel Boston

The Midtown Hotel MOD Collection by Sonesta

The Midtown Hotel MOD Collection by Sonesta
2.0 star property
Prudential - St. Botolph, 1.8 km from Medical Center Area
7.6 out of 10, Good, (1,008 reviews)
"Very clean and nice rooms. The hotel staff is also very kind."
United States
James
The price is ₩143,544
₩167,157 total
includes taxes & fees
Feb 2 - Feb 3
The Midtown Hotel MOD Collection by Sonesta

The Revolution Hotel

The Revolution Hotel
3.5 star property
2.8 km from Medical Center Area
9.0 out of 10, Wonderful, (2,422 reviews)
"Great stay! Clean room, kind staff, and excellent location. Would stay here again and would recommend "
United States
Mia Lian
The price is ₩114,835
₩133,724 total
includes taxes & fees
Feb 1 - Feb 2
The Revolution Hotel

Moxy Boston Downtown

Moxy Boston Downtown
3.5 star property
Bay Village, 3.5 km from Medical Center Area
8.8 out of 10, Excellent, (1,027 reviews)
"Clean rooms, friendly staff, nice bar area. "
United States
Jessica
The price is ₩130,784
₩211,939 total
includes taxes & fees
Feb 2 - Feb 3
Moxy Boston Downtown

DoubleTree by Hilton Boston - Downtown

DoubleTree by Hilton Boston - Downtown
4.0 star property
Bay Village, 3.4 km from Medical Center Area
8.8 out of 10, Excellent, (1,016 reviews)
"Great staff, comfortable beds"
United States
Jeffrey
The price is ₩160,196
₩186,549 total
includes taxes & fees
Feb 1 - Feb 2
DoubleTree by Hilton Boston - Downtown

Found Hotel Boston Common

Found Hotel Boston Common
2.5 star property
Theatre District, 3.3 km from Medical Center Area
8.4 out of 10, Very Good, (1,306 reviews)
"It was great stay. "
United States
Christopher
The price is ₩117,531
₩136,865 total
includes taxes & fees
Feb 2 - Feb 3
Found Hotel Boston Common
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Medical Center Area

Find the best Medical Center Area areas and neighborhoods for the activities you enjoy most.

Downtown Boston

Densely packed with highrise buildings, this area boasts landmarks like Custom House Tower and is close to Quincy Market, Faneuil Hall, and the Old State House. Find headquarters of major banks, hotels, and investment firms here.

Seaport District

Experience a transformed industrial area with office towers, innovation labs, and 78 restaurants. Visit the Institute of Contemporary Art and easily access Downtown Boston via the Evelyn Moakley Bridge.

Back Bay

Victorian brownstone homes and cultural institutions like the Boston Public Library define this area. Shop at Newbury Street, Prudential Center, and Copley Place, or explore sights like Trinity Church and the John Hancock Tower.

Beacon Hill

Historic Federal-style rowhouses, gaslit streets, and brick sidewalks create a charming atmosphere. Explore the Boston African American National Historic Site, shop on Charles Street, and easily access MBTA stations.

North End

Indulge in Italian cuisine at numerous restaurants and bakeries, explore historic sites like Old North Church and Paul Revere House, and enjoy performances at NEMPAC and Improv Asylum Theater. Easily accessible via MBTA lines, buses, and ferries.

Top Medical Center Area Hotel Reviews

Frequently asked questions

What's it like in Medical Center Area?
Guests are sure to enjoy their time checking out all that Boston's Medical Center Area neighborhood has to offer. Be sure to check out Isabella Stewart Gardner Museum and Warren Anatomical Museum as part of your Medical Center Area travel plans.
What's a favorite hotel to stay in Medical Center Area?
Based on Expedia customer reviews, The Inn at Longwood Medical is the highest ranked property in Medical Center Area. This hotel is a short 1-minute walk from Children's Hospital Boston, and it offers a restaurant and a fitness center.
How many hotels are there in Medical Center Area?
When you want to kick up your feet after a day of exploring the sights in Boston, you can choose from 17 Expedia hotels and other accommodations in Medical Center Area.
If I need to cancel my hotel reservation in Medical Center Area, will I receive a refund?
Yes, most hotel room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to get the best deals available in Medical Center Area.
Where can I learn more about changing or cancelling my trip to Medical Center Area?
For more information about updating your trip to Medical Center Area or cancelling it, go to https://www.expedia.com/service/.
What can I see and do in this Boston neighborhood?
Sights like Isabella Stewart Gardner Museum and Warren Anatomical Museum can be part of your cultural tour of Medical Center Area. When you're sightseeing in Boston, Fenway Park and TD Garden are also worth a stop.
How can I get around Medical Center Area and the greater Boston area?
If you want to see more of the city, Longwood Medical Area Station is the closest metro stop. Others nearby include Brigham Circle Station and Museum of Fine Arts Station.