What is Midtown like?

Travelers are sure to enjoy a stay in St. Louis's Midtown neighborhood. Be sure to check out Chaifetz Arena and Washington Avenue Historic District as part of your Midtown travel plans.

Where is the best place to stay in Midtown?

Based on our traveler data, Element by Marriott St. Louis Midtown is one of the top choices for your stay in Midtown. This hotel is a short 6-minute walk from St. Louis University, and it offers free breakfast and an indoor pool.

How many hotels will I be able to find in the Midtown area?

If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 36 Midtown hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in Midtown, will I receive a refund?

Yes, most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and get a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get the best options available in Midtown.

Where can I learn more about changing or cancelling my trip to Midtown?

To access more information about picking new dates or cancelling your trip to Midtown, go to https://www.expedia.com/service/ .

What are the top things to see and do in Midtown?

Sights like Red Flag, Scott Joplin House State Historic Site, and Museum of Contemporary Religious Art can be part of your cultural tour of Midtown. Chaifetz Arena and Washington Avenue Historic District are also a couple of places to visit in the neighborhood. St. Louis Union Station, Hermann Stadium, and .ZACK Theater are just a few of the places to visit in and around Midtown. While you're out sightseeing, Fubar and The Sovereign - St. Louis are a couple of additional sights to visit in St. Louis.

How can I get around Midtown and the greater St. Louis area?

Ready to get out and explore the city? Grand Station is the closest metro station.

Top Midtown Hotels

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Our top choices for Midtown hotels

An outdoor patio area with seating, planters, and a grill.

1. Element by Marriott St. Louis Midtown

Midtown

Julie

₩223,367 total

includes taxes & fees

Nov 23 - Nov 24

An outdoor patio area with seating, a fire pit, and a grill.

2. Residence Inn by Marriott St Louis Downtown

Midtown

Kirsten

₩174,761 total

includes taxes & fees

Nov 22 - Nov 23

A rooftop terrace with outdoor seating, string lights, and a city skyline view.

3. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

0.8 km from Midtown

Stephanie

₩162,798 total

includes taxes & fees

Nov 23 - Nov 24

A modern bar area with a wooden bar counter, black bar stools, and a large wall with city names.

4. Fairfield Inn & Suites by Marriott St. Louis Downtown

Downtown West, 1.3 km from Midtown

Demarco

₩174,743 total

includes taxes & fees

Nov 29 - Nov 30

A bar area with high wooden ceilings, a large mural, and a variety of seating options including tables and bar stools.

5. 21C Museum Hotel St Louis

Downtown West, 2.1 km from Midtown

A.R.

₩231,077 total

includes taxes & fees

Dec 9 - Dec 10

An indoor swimming pool with a hot tub, lounge chairs, and a brick wall with artwork.

6. Pear Tree Inn St. Louis Near Union Station

Downtown West, 1.2 km from Midtown

Samuwel

₩162,433 total

includes taxes & fees

Nov 29 - Nov 30

An indoor pool area with a hot tub, seating, and a stone wall.

7. Drury Plaza Hotel St. Louis Union Station

Downtown West, 1.5 km from Midtown

gina

₩180,492 total

includes taxes & fees

Nov 29 - Nov 30

A spacious lobby with high arched ceilings, ornate columns, and a central fountain.

8. St. Louis Union Station Hotel, Curio Collection by Hilton

Downtown West, 1.7 km from Midtown

William

₩246,130 total

includes taxes & fees

Nov 26 - Nov 27

A Comfort Inn & Suites hotel with a modern design, featuring a covered entrance and a brick facade.

9. Comfort Inn & Suites Saint Louis Lafayette Square

The Gate, 2 km from Midtown

Michelle

₩169,353 total

includes taxes & fees

Dec 6 - Dec 7

The exterior of the Clark & Bourbon hotel with a well-lit entrance, a marquee sign, and a landscaped planter area.

10. Live by Loews - St.Louis

Downtown St. Louis, 3 km from Midtown

brandon

₩220,831 total

includes taxes & fees

Nov 15 - Nov 16

A lobby with a sofa, two armchairs, a coffee table, and a staircase.

11. Hyatt Regency St. Louis at The Arch

Downtown St. Louis, 3.4 km from Midtown

Tracy

₩168,721 total

includes taxes & fees

Nov 26 - Nov 27

An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

12. Home2 Suites by Hilton St. Louis/Forest Park

The Grove, 3 km from Midtown

Ruth

₩222,227 total

includes taxes & fees

Dec 7 - Dec 8

A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.

13. Embassy Suites by Hilton St. Louis Downtown

Downtown St. Louis, 3.1 km from Midtown

Megan

₩168,366 total

includes taxes & fees

Dec 10 - Dec 11

An outdoor dining area with a glass table and chairs, a neon sign, and a city view.

14. Aloft by Marriott St Louis Central West End

Central West End, 2.2 km from Midtown

Brittany

₩177,913 total

includes taxes & fees

Nov 16 - Nov 17

A modern kitchen with a hexagonal tile backsplash, built-in appliances, and a central island.

15. Tru By Hilton St. Louis Downtown

Downtown West, 2.5 km from Midtown

Arthur

₩115,511 total

includes taxes & fees

Dec 11 - Dec 12

An indoor swimming pool with clear glass ceilings, large windows, and a sunlit area with umbrellas.

16. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Downtown St. Louis, 3.5 km from Midtown

Andrew

₩165,228 total

includes taxes & fees

Nov 23 - Nov 24

A rooftop terrace with wicker furniture, offering a city view.

17. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis, 3.4 km from Midtown

Nicole

₩224,913 total

includes taxes & fees

Nov 17 - Nov 18

A modern hotel room with a large bed, a nightstand, a mirror, and a view of the city through arched windows.

18. The Westin St. Louis

Downtown St. Louis, 2.9 km from Midtown

Stacy

₩191,064 total

includes taxes & fees

Nov 23 - Nov 24

A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

19. The Royal Sonesta Chase Park Plaza St. Louis

Central West End, 3.6 km from Midtown

Sara

₩250,479 total

includes taxes & fees

Nov 23 - Nov 24

A modern living room with a fireplace, sofas, a coffee table, and a bookshelf.

20. AC Hotel St. Louis Central West End

Central West End, 3.4 km from Midtown

Janice

₩226,301 total

includes taxes & fees

Nov 23 - Nov 24

View all properties

Compare top hotels in Midtown

Element by Marriott St. Louis Midtown 3.0 star property Midtown View	Residence Inn by Marriott St Louis Downtown 3.0 star property Midtown View	Angad Arts Hotel St. Louis, Tapestry Collection by Hilton 4.0 star property 0.8 km from Midtown View	Fairfield Inn & Suites by Marriott St. Louis Downtown 3.0 star property Downtown West, 1.3 km from Midtown View	21C Museum Hotel St Louis 4.5 star property Downtown West, 2.1 km from Midtown View
8.8 Excellent 859 reviews	7.6 Good 1,000 reviews	8.8 Excellent 1,167 reviews	9.2 Wonderful 1,000 reviews	9.0 Wonderful 2,153 reviews
The price is ₩191,028 ₩223,367 total includes taxes & fees Nov 23 - Nov 24	The price is ₩146,945 ₩174,761 total includes taxes & fees Nov 22 - Nov 23	The price is ₩138,048 ₩162,798 total includes taxes & fees Nov 23 - Nov 24	The price is ₩146,477 ₩174,743 total includes taxes & fees Nov 29 - Nov 30	The price is ₩191,910 ₩231,077 total includes taxes & fees Dec 9 - Dec 10
Yes, Breakfast included Yes, Pool No Spa Yes, Pet friendly Yes, WiFi included Yes, Parking	No Breakfast included Yes, Pool No Spa Yes, Pet friendly Yes, WiFi included Yes, Parking	No Breakfast included No Pool No Spa Yes, Pet friendly Yes, WiFi included Yes, Parking	Yes, Breakfast included No Pool No Spa No Pet friendly Yes, WiFi included Yes, Parking	No Breakfast included Yes, Pool Yes, Spa Yes, Pet friendly Yes, WiFi included Yes, Parking

Where to stay in Midtown

Find the best Midtown areas and neighborhoods for the activities you enjoy most.

The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Old Courthouse or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

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A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

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A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

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A historic building with a green dome and adjacent modern high-rise buildings.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

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A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

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Top Midtown Hotel Reviews

Sonesta ES Suites St. Louis - Chesterfield

10/10 Excellent

"Great place to stay at a great price!!! Always sparkly clean! Wish the furniture was more comfortable but the bed is wonderful!"

21C Museum Hotel St Louis

10/10 Excellent

"This is by far my favorite hotel. It is always clean, the staff is very kind and helpful, the gym and hot tub is SO COOL and huge. One of the most unique hotels I’ve ever stayed in. Rooms are very comfortable, they leave water, chocolates, and a robe for you. Sometimes they even give you a complimentary whiskey. The dinner menu isn’t as good as it used to be and breakfast is overpriced but the atmosphere truly makes up for it. Theres a museum on the second floor, a pool table, a really cool stairwell of colors and art. I would recommend this hotel 100x."

Ameristar Casino Resort and Spa

8/10 Good

"We were here for a wedding. Our room was very nice but my son’s bathroom was disgusting and not clean, they had to switch rooms and the only compensation they gave them was a food voucher. Not acceptable with blood and vomit not cleaned from previous guest. We expected more for this caliber of hotel."

Find hotels in Midtown, St. Louis

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Treat yourself

Be picky

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Midtown hotels

1. Element by Marriott St. Louis Midtown

2. Residence Inn by Marriott St Louis Downtown

3. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4. Fairfield Inn & Suites by Marriott St. Louis Downtown

5. 21C Museum Hotel St Louis

6. Pear Tree Inn St. Louis Near Union Station

7. Drury Plaza Hotel St. Louis Union Station

8. St. Louis Union Station Hotel, Curio Collection by Hilton

9. Comfort Inn & Suites Saint Louis Lafayette Square

10. Live by Loews - St.Louis

11. Hyatt Regency St. Louis at The Arch

12. Home2 Suites by Hilton St. Louis/Forest Park

13. Embassy Suites by Hilton St. Louis Downtown

14. Aloft by Marriott St Louis Central West End

15. Tru By Hilton St. Louis Downtown

16. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

17. Drury Plaza Hotel St. Louis at the Arch

18. The Westin St. Louis

19. The Royal Sonesta Chase Park Plaza St. Louis

20. AC Hotel St. Louis Central West End

Compare top hotels in Midtown

Element by Marriott St. Louis Midtown

Residence Inn by Marriott St Louis Downtown

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Fairfield Inn & Suites by Marriott St. Louis Downtown

21C Museum Hotel St Louis

Where to stay in Midtown

Downtown St. Louis

Clayton

St. Charles Historic District

Central West End

Creve Coeur

Top Midtown Hotel Reviews

Sonesta ES Suites St. Louis - Chesterfield

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