Find hotels in Santa Ana, Antigua Guatemala

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Our top choices for Santa Ana hotels

Villas Santa Ana-Ricardo

Villas Santa Ana-Ricardo
3.5 star property
Santa Ana
8.6 out of 10, Excellent, (12 reviews)
"Space was clean and had a cozy vibe."
United States
Evelin
Villas Santa Ana-Ricardo

Hostal Casa Buho

Hostal Casa Buho
3.0 star property
Santa Ana
8.6 out of 10, Excellent, (22 reviews)
"A little too far from everything but as long as you have a car is ok plenty of parking there"
United States
Gustavo
The price is ₩68,057
₩83,030 total
includes taxes & fees
Feb 13 - Feb 14
Hostal Casa Buho

Casa Buho B&B

Casa Buho B&B
3.0 star property
Santa Ana
9.2 out of 10, Wonderful, (49 reviews)
"Great place !!"
United States
Abner Israel Polanco
The price is ₩76,848
₩93,755 total
includes taxes & fees
Feb 1 - Feb 2
Casa Buho B&B

Hotel y Restaurante Vista Verde

Hotel y Restaurante Vista Verde
3.0 star property
5.9 km from Santa Ana
10.0 out of 10, Exceptional, (3 reviews)
"Great room (#3) with high quality mattress, nice towels and pretty bathroom, lacks some toiletries, quiete place with awesome graden views, property rune by their owners, highly recommended! "
United States
Sergio
The price is ₩95,774
₩116,844 total
includes taxes & fees
Feb 7 - Feb 8
Hotel y Restaurante Vista Verde

Hotel La Posadita Antigua

Hotel La Posadita Antigua
3.0 star property
1.9 km from Santa Ana
8.8 out of 10, Excellent, (45 reviews)
"Nice place to stay and good location "
United States
Alfredo
Hotel La Posadita Antigua

Hotel Genessis

Hotel Genessis
3.5 star property
0.9 km from Santa Ana
9.2 out of 10, Wonderful, (108 reviews)
"Gorgeous gorgeous hotel! Staff was so friendly! Will definitely stay here again!"
United States
Sandy
Hotel Genessis

Don Valentino

Don Valentino
3.5 star property
Historic Center, 1.6 km from Santa Ana
7.4 out of 10, Good, (77 reviews)
"Great service! Clean rooms and the young guy in front desk was very attentive and helpful. "
United States
Azucena
The price is ₩72,624
₩88,601 total
includes taxes & fees
Feb 26 - Feb 27
Don Valentino

Hotel Posada del Angel

Hotel Posada del Angel
4.0 star property
1 km from Santa Ana
9.6 out of 10, Exceptional, (284 reviews)
"The breakfast on the rooftop where we could watch the volcano erupt was spectacular. Breakfast was delicious and service was top notch. We stayed in the Rose Suite and loved it."
United States
Amelia
Hotel Posada del Angel

Luna Maya Boutique Hotel

Luna Maya Boutique Hotel
3.0 star property
1.5 km from Santa Ana
9.6 out of 10, Exceptional, (27 reviews)
"Nice staff , nice breakfast "
United States
Lesly
The price is ₩94,273
₩115,014 total
includes taxes & fees
Feb 4 - Feb 5
Luna Maya Boutique Hotel

Narama zona 13

Narama zona 13
4.0 star property
21.3 km from Santa Ana
8.8 out of 10, Excellent, (21 reviews)
"I chose this place because it was close to the airport, very comfortable bed and very clean very modern and and highly decorated"
United States
yussef
Narama zona 13

Hotel Cacique Real

Hotel Cacique Real
3.0 star property
1.8 km from Santa Ana
8.8 out of 10, Excellent, (166 reviews)
"Very clean rooms and nice outdoor area plus secure parking lot"
United States
Ephraim
Hotel Cacique Real

Hotel Posada San Vicente

Hotel Posada San Vicente
2.5 star property
Historic Center, 1.4 km from Santa Ana
8.0 out of 10, Very Good, (212 reviews)
"Staff is great plus the location "
Canada
RICHARD
The price is ₩75,333
₩91,906 total
includes taxes & fees
Feb 26 - Feb 27
Hotel Posada San Vicente

Hotel Meson de Maria

Hotel Meson de Maria
3.5 star property
Historic Center, 1.6 km from Santa Ana
9.0 out of 10, Wonderful, (194 reviews)
"Clean room, friendly staff, great hotel overall. However the wifi wasn't great."
United States
Michael
Hotel Meson de Maria

Pensativo House Hotel

Pensativo House Hotel
4.5 star property
1 km from Santa Ana
9.4 out of 10, Exceptional, (394 reviews)
"Rooms were clean and bed and pillows were comfortable with good A/C. Staff was very helpful and were always ready to assist. Food was excellent. "
United States
Carlos Alvarez
Pensativo House Hotel

Indian Palace

Indian Palace
3.0 star property
2.8 km from Santa Ana
9.0 out of 10, Wonderful, (31 reviews)
"Beautiful view to the volcanics clean area Beautiful pool, good game room i will recommend."
United States
Estuardo
The price is ₩96,499
₩117,729 total
includes taxes & fees
Feb 3 - Feb 4
Indian Palace

EL TEJAR HOSTAL

EL TEJAR HOSTAL
3.0 star property
21 km from Santa Ana
8.0 out of 10, Very Good, (17 reviews)
"Staff very friendly and helpful. Room clean and quiet. "
United States
ILEANA
The price is ₩60,417
₩73,709 total
includes taxes & fees
Jan 30 - Jan 31
EL TEJAR HOSTAL

Hotel Las Marías

Hotel Las Marías
3.0 star property
1.9 km from Santa Ana
9.2 out of 10, Wonderful, (435 reviews)
"clean room in a good area"
United States
roghayeh
The price is ₩120,418
₩146,910 total
includes taxes & fees
Feb 1 - Feb 2
Hotel Las Marías

Ciel-Luxe Hotels

Ciel-Luxe Hotels
3.5 star property
Historic Center, 1.4 km from Santa Ana
8.6 out of 10, Excellent, (370 reviews)
"Friendly and accomadating staff"
United States
Kaushal
Ciel-Luxe Hotels

Casa Noble Hotel

Casa Noble Hotel
3.0 star property
0.9 km from Santa Ana
9.6 out of 10, Exceptional, (182 reviews)
"Very nice place!"
Canada
Zaul
The price is ₩154,377
₩188,340 total
includes taxes & fees
Feb 4 - Feb 5
Casa Noble Hotel

Hotel Casa Bansley

Hotel Casa Bansley
2.5 star property
2.3 km from Santa Ana
9.8 out of 10, Exceptional, (49 reviews)
"Property is beautiful and staff are great"
United States
Michael
The price is ₩151,510
₩184,842 total
includes taxes & fees
Feb 5 - Feb 6
Hotel Casa Bansley
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.

Historic Center

While visiting Historic Center, you might make a stop by sights like Central Park and Santa Catalina Arch.

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Top Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Santa Ana?
Travelers to the Santa Ana neighborhood in Antigua Guatemala will be sure to enjoy their stay.
What's a favorite hotel to stay in Santa Ana?
Based on Expedia customer reviews, Casa Buho B&B is the highest ranked property in Santa Ana. This hotel offers a restaurant and free parking. Another top choice in the area is Hostal Casa Buho.
How many hotels will I be able to find in Santa Ana?
If you're searching for places to stay in Antigua Guatemala, choose from one of Expedia's 16 hotels and other accommodations in Santa Ana.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to review the top deals on offer in Santa Ana.
Where can I learn more about changing or cancelling my trip to Santa Ana?
To find more details about updating your trip to Santa Ana or cancelling it, click here.
What are the top things to see and do in Santa Ana?
House of the Giants, Santa Clara Convent, and Jade Maya Factory and Museum are just a few of the places to visit in and around Santa Ana. While you're out sightseeing in Antigua Guatemala, be sure to visit other sights like Tanque La Unión or Museo del Hermano Pedro.