Find hotels in Santa Ana, Antigua Guatemala

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Our top choices for Santa Ana hotels

Hostal Casa Buho

Hostal Casa Buho
3.0 star property
Santa Ana
8.6 out of 10, Excellent, (23 reviews)
"A little too far from everything but as long as you have a car is ok plenty of parking there"
United States
Gustavo
The price is ₩71,334
₩87,027 total
includes taxes & fees
Apr 1 - Apr 2
Hostal Casa Buho

Villas Santa Ana-Ricardo

Villas Santa Ana-Ricardo
3.5 star property
Santa Ana
8.8 out of 10, Excellent, (14 reviews)
"Space was clean and had a cozy vibe."
United States
Evelin
The price is ₩192,158
₩234,433 total
includes taxes & fees
Mar 25 - Mar 26
Villas Santa Ana-Ricardo

Casa Buho B&B

Casa Buho B&B
3.0 star property
Santa Ana
9.2 out of 10, Wonderful, (51 reviews)
"Beautiful hotel with clean rooms and friendly staff. The only downsides are the distance to the center (a 30-minute walk) and the chickens and peacocks screaming early in the morning"
United States
Patrick
The price is ₩98,380
₩120,024 total
includes taxes & fees
Mar 17 - Mar 18
Casa Buho B&B

Hilton Guatemala City

Hilton Guatemala City
4.5 star property
25.9 km from Santa Ana
8.6 out of 10, Excellent, (699 reviews)
"The hotel property in excellent condition and very quiet and safe."
United States
Roger
The price is ₩159,420
₩194,492 total
includes taxes & fees
Apr 5 - Apr 6
Hilton Guatemala City

AC Hotel by Marriott Guatemala City

AC Hotel by Marriott Guatemala City
4.0 star property
26.4 km from Santa Ana
8.6 out of 10, Excellent, (1,001 reviews)
"Great location and pricing."
United States
JULIO
The price is ₩164,290
₩200,433 total
includes taxes & fees
Mar 22 - Mar 23
AC Hotel by Marriott Guatemala City

Hotel Vista Quince

Hotel Vista Quince
5.0 star property
25.5 km from Santa Ana
8.6 out of 10, Excellent, (244 reviews)
"We really enjoyed our stay, everything was great- we will be returning "
United States
Lucy
The price is ₩209,763
₩255,911 total
includes taxes & fees
Mar 20 - Mar 21
Hotel Vista Quince

Villas Santander - Deluxe Stay

Villas Santander - Deluxe Stay
3.0 star property
24.7 km from Santa Ana
7.4 out of 10, Good, (241 reviews)
"Horrible architecture, poor infrastructure. Half-baked."
United States
Alan
The price is ₩52,798
₩64,414 total
includes taxes & fees
Mar 17 - Mar 18
Villas Santander - Deluxe Stay

Villa Sicilia

Villa Sicilia
2.0 star property
24 km from Santa Ana
8.0 out of 10, Very Good, (116 reviews)
"Room was clean, staff were pleasant, good location. Enjoyed my stay and would return again!"
United States
Dejanera
The price is ₩38,468
₩46,931 total
includes taxes & fees
Apr 12 - Apr 13
Villa Sicilia

Ever Green Hotel

Ever Green Hotel
3.5 star property
23.8 km from Santa Ana
9.0 out of 10, Wonderful, (73 reviews)
"Great room, nice location and decent complimentary breakfast. We would stay again. Great value"
United States
Rony
Ever Green Hotel

Hotel Antigua Inn

Hotel Antigua Inn
3.5 star property
23.8 km from Santa Ana
8.2 out of 10, Very Good, (69 reviews)
"Exelente hotel and location and friendly people. "
United States
Rudy A
Hotel Antigua Inn

La Inmaculada Hotel

La Inmaculada Hotel
3.5 star property
23.7 km from Santa Ana
9.2 out of 10, Wonderful, (629 reviews)
"Great staff, convenient location, hotel has everything it offers."
United States
Colin
The price is ₩147,370
₩179,791 total
includes taxes & fees
Apr 1 - Apr 2
La Inmaculada Hotel

Hotel Ciudad Vieja

Hotel Ciudad Vieja
3.0 star property
23.7 km from Santa Ana
9.2 out of 10, Wonderful, (229 reviews)
"Excellent spot! Garden oasis!"
United States
kathleen
Hotel Ciudad Vieja

Meraki Boutique Hotel

Meraki Boutique Hotel
3.5 star property
23.4 km from Santa Ana
9.0 out of 10, Wonderful, (419 reviews)
"It is a boutique hotel with comfortable beds, good AC and a great breakfast. The rooms are small but comfortable and the hotel is well run and in a good location. The staff are very helpful and the 24 hour front desk ensured that I got to the airport at 3:30AM. I'll stay there again. "
United States
Gary
The price is ₩120,995
₩147,614 total
includes taxes & fees
Mar 29 - Mar 30
Meraki Boutique Hotel

Hotel Santander Plaza

Hotel Santander Plaza
3.5 star property
23.3 km from Santa Ana
8.2 out of 10, Very Good, (586 reviews)
"Breakfast was delicious with a lot of options to choose, staff very kind good service "
United States
Monica
The price is ₩147,328
₩179,740 total
includes taxes & fees
Mar 17 - Mar 18
Hotel Santander Plaza

Clarion Suites Guatemala City

Clarion Suites Guatemala City
4.0 star property
23.3 km from Santa Ana
9.2 out of 10, Wonderful, (1,010 reviews)
"Large room, clean, excellent staff "
Canada
Kathy
The price is ₩140,729
₩171,689 total
includes taxes & fees
Apr 6 - Apr 7
Clarion Suites Guatemala City

Good Hotel Guatemala City

Good Hotel Guatemala City
3.0 star property
23.9 km from Santa Ana
9.4 out of 10, Exceptional, (300 reviews)
"Really liked this location is great "
United States
Malika
The price is ₩173,569
₩211,754 total
includes taxes & fees
Mar 21 - Mar 22
Good Hotel Guatemala City

Hyatt Centric Guatemala City

Hyatt Centric Guatemala City
4.5 star property
23.3 km from Santa Ana
9.6 out of 10, Exceptional, (858 reviews)
"Hotel was beautiful and impeccable! Staff was amazing! "
United States
Nordy
The price is ₩184,667
₩225,294 total
includes taxes & fees
Mar 28 - Mar 29
Hyatt Centric Guatemala City

Best Western Plus Hotel Stofella

Best Western Plus Hotel Stofella
4.0 star property
23.3 km from Santa Ana
8.8 out of 10, Excellent, (1,001 reviews)
"Great breakfast buffet"
United States
Loyell
The price is ₩137,425
₩167,661 total
includes taxes & fees
Mar 27 - Mar 28
Best Western Plus Hotel Stofella

InterContinental Real Guatemala by IHG

InterContinental Real Guatemala by IHG
5.0 star property
23.2 km from Santa Ana
9.2 out of 10, Wonderful, (1,002 reviews)
"Very nice room and service was great! "
United States
Henry
The price is ₩214,258
₩279,674 total
includes taxes & fees
Apr 5 - Apr 6
InterContinental Real Guatemala by IHG

Hotel Royal Palace

Hotel Royal Palace
3.0 star property
24.5 km from Santa Ana
8.2 out of 10, Very Good, (152 reviews)
"The hotel is well located there is a lot of stores and restaurants with in a walking distance."
United States
luis
The price is ₩138,009
₩168,365 total
includes taxes & fees
Mar 18 - Mar 19
Hotel Royal Palace
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.

Historic Center

While visiting Historic Center, you might make a stop by sights like Central Park and Santa Catalina Arch.

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Top Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Santa Ana?
Travelers to the Santa Ana neighborhood in Antigua Guatemala will be sure to enjoy their stay.
What's a favorite hotel to stay in Santa Ana?
Based on Expedia customer reviews, Casa Buho B&B is the highest ranked property in Santa Ana. This hotel offers a restaurant and free parking. Another top choice in the area is Hostal Casa Buho.
How many hotels will I be able to find in Santa Ana?
If you're searching for places to stay in Antigua Guatemala, choose from one of Expedia's 15 hotels and other accommodations in Santa Ana.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to review the top deals on offer in Santa Ana.
Where can I learn more about changing or cancelling my trip to Santa Ana?
To find more details about updating your trip to Santa Ana or cancelling it, click here.
What are the top things to see and do in Santa Ana?
House of the Giants, Santa Clara Convent, and Jade Maya Factory and Museum are just a few of the places to visit in and around Santa Ana. While you're out sightseeing in Antigua Guatemala, be sure to visit other sights like Tanque La Unión or Museo del Hermano Pedro.