Find hotels in Santa Ana, Antigua Guatemala from ₩41,207

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Discover 1,219 Santa Ana hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Interior
Casa Buho B&B
Casa Buho B&B
3.0 star property
9.2 out of 10, Wonderful, (46)
"All was very good and True to the pictures "
United States
Xavier
The price is ₩93,301
₩113,827 total
includes taxes & fees
Nov 28 - Nov 29
Casa Buho B&B
Garden view
Hostal Casa Buho
Hostal Casa Buho
3.0 star property
8.6 out of 10, Excellent, (21)
"We had a wonderful time "
United States
Mynor
Hostal Casa Buho
Front of property
Villas Santa Ana-Ricardo
Villas Santa Ana-Ricardo
3.5 star property
8.4 out of 10, Very Good, (11)
"Very nice place"
United States
Maynor
Villas Santa Ana-Ricardo
Living area
La guarida del caudillo
La guarida del caudillo
1.0 star property
The price is ₩39,246
₩47,881 total
includes taxes & fees
Nov 5 - Nov 6
La guarida del caudillo
Living area
Castillo De Los Gigantes
Castillo De Los Gigantes
2.0 star property
The price is ₩33,776
₩41,207 total
includes taxes & fees
Nov 5 - Nov 6
Castillo De Los Gigantes
Indoor wedding
Barceló Guatemala City
Barceló Guatemala City
4.5 star property
9.2 out of 10, Wonderful, (3073)
"Good hotel very close to airport"
United States
Robert
The price is ₩157,238
₩191,831 total
includes taxes & fees
Nov 28 - Nov 29
Barceló Guatemala City
3 outdoor pools, pool umbrellas
Hotel Soleil La Antigua
Hotel Soleil La Antigua
4.0 star property
8.6 out of 10, Excellent, (1002)
"All staff are nice, excellent service, good price, good location. The people of Guatemala are very kind!!!"
United States
Nancy
Hotel Soleil La Antigua
Fitness studio
Hotel Museo Spa Casa Santo Domingo
Hotel Museo Spa Casa Santo Domingo
4.5 star property
9.2 out of 10, Wonderful, (1006)
"Will definitely be returning here!"
United States
Axel
The price is ₩383,662
₩485,403 total
includes taxes & fees
Nov 5 - Nov 6
Hotel Museo Spa Casa Santo Domingo
Terrace/patio
Los Pasos Boutique Hotel & Spa
Los Pasos Boutique Hotel & Spa
4.5 star property
9.4 out of 10, Exceptional, (1004)
"It a beautiful property and everyone was extremely polite, attentive and accommodating! This property is walking distance from the cathedral and main square. Very safe area. Thank you all for your kindness we will be back!"
United States
Maritza
The price is ₩186,541
₩227,580 total
includes taxes & fees
Nov 5 - Nov 6
Los Pasos Boutique Hotel & Spa
Egyptian cotton sheets, premium bedding, in-room safe, desk
El Convento Boutique Hotel
El Convento Boutique Hotel
4.0 star property
9.4 out of 10, Exceptional, (781)
"Great hotel!"
United States
Rafael
The price is ₩283,340
₩367,140 total
includes taxes & fees
Nov 16 - Nov 17
El Convento Boutique Hotel
Breakfast, lunch, dinner served; international cuisine, garden views
Clarion Suites Guatemala City
Clarion Suites Guatemala City
4.0 star property
9.0 out of 10, Wonderful, (1002)
"Excellent hotel !! "
United States
Sergio
The price is ₩149,202
₩182,026 total
includes taxes & fees
Nov 28 - Nov 29
Clarion Suites Guatemala City
4 restaurants, breakfast, lunch, dinner served; international cuisine
InterContinental Real Guatemala by IHG
InterContinental Real Guatemala by IHG
5.0 star property
9.2 out of 10, Wonderful, (1010)
"Overall great hotel with excellent service."
Canada
Pierre
The price is ₩241,841
₩312,504 total
includes taxes & fees
Nov 23 - Nov 24
InterContinental Real Guatemala by IHG
Outdoor pool
Hyatt Centric Guatemala City
Hyatt Centric Guatemala City
4.5 star property
9.6 out of 10, Exceptional, (762)
"Excelente Hotel "
Mexico
Blanca
The price is ₩230,393
₩281,079 total
includes taxes & fees
Nov 14 - Nov 15
Hyatt Centric Guatemala City
Exterior
Naif Boutique Hotel
Naif Boutique Hotel
3.0 star property
8.8 out of 10, Excellent, (357)
"Absolutely recommend to stay here great stay !! "
United States
Brianna
The price is ₩159,242
₩194,275 total
includes taxes & fees
Nov 10 - Nov 11
Naif Boutique Hotel
2 treatment rooms
Hotel Las Americas
Hotel Las Americas
4.0 star property
8.4 out of 10, Very Good, (1001)
"The breakfast is great. "
United States
Darrol
The price is ₩122,999
₩150,059 total
includes taxes & fees
Nov 2 - Nov 3
Hotel Las Americas
Exterior
All Suite El Marques de Antigua
All Suite El Marques de Antigua
3.5 star property
9.2 out of 10, Wonderful, (285)
"Had a wonderful stay! The location was perfect for sightseeing, and the hotel staff made us feel at home. Rooms were clean, spacious, and had all the amenities we needed. I highly recommend it"
United States
juan
All Suite El Marques de Antigua
Front of property
Mestizo Cortijo
Mestizo Cortijo
3.0 star property
9.0 out of 10, Wonderful, (85)
"I enjoyed my stay there. Absolutely amazing. Will definitely go back. "
United States
Makayla
The price is ₩176,372
₩215,174 total
includes taxes & fees
Nov 30 - Dec 1
Mestizo Cortijo
Exterior
Hotel Posada de Don Rodrigo Antigua
Hotel Posada de Don Rodrigo Antigua
3.5 star property
9.4 out of 10, Exceptional, (629)
"Great hotel right in the center of the action. The facilities and hotel vibes are awesome! The restaurant has great food and all the staff is kind all around. The beds I found to be uncomfortable, but not a deal breaker as the hotel pros outweigh the cons. "
United States
Juan
The price is ₩228,918
₩313,952 total
includes taxes & fees
Nov 11 - Nov 12
Hotel Posada de Don Rodrigo Antigua
Terrace/patio
In & Out Hotel
In & Out Hotel
3.0 star property
8.4 out of 10, Very Good, (783)
"Breakfast included "
United States
Chelsea
In & Out Hotel
Exterior
Hotel Casa Carmina
Hotel Casa Carmina
4.0 star property
9.0 out of 10, Wonderful, (183)
"Nice hotel great staff "
United States
Judy
The price is ₩172,579
₩210,547 total
includes taxes & fees
Nov 1 - Nov 2
Hotel Casa Carmina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.

Historic Center

While visiting Historic Center, you might make a stop by sights like Central Park and Santa Catalina Arch.

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Top Santa Ana Hotel Reviews

Wyndham Garden Guatemala City

Wyndham Garden Guatemala City

10/10 Excellent
"I would stay here again. The staff was wonderful and so was the hotel. The amenities were also great!"
Daisy 1-night trip
Posted 3 days ago
Wyndham Garden Guatemala City

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Frequently asked questions

What's it like in Santa Ana?
Travelers to the Santa Ana neighborhood in Antigua Guatemala will be sure to enjoy their stay.
What's a favorite hotel to stay in Santa Ana?
Based on Expedia customer reviews, Casa Buho B&B is the highest ranked property in Santa Ana. This hotel offers a restaurant and free parking.
How many hotels will I be able to find in Santa Ana?
If you're searching for places to stay in Antigua Guatemala, choose from one of Expedia's 18 hotels and other accommodations in Santa Ana.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to review the top deals on offer in Santa Ana.
Where can I learn more about changing or cancelling my trip to Santa Ana?
To find more details about updating your trip to Santa Ana or cancelling it, click here.
What are the top things to see and do in Santa Ana?
House of the Giants, Santa Clara Convent, and Jade Maya Factory and Museum are just a few of the places to visit in and around Santa Ana. While you're out sightseeing in Antigua Guatemala, be sure to visit other sights like Tanque La Unión or Museo del Hermano Pedro.