Santa Clara
Panama City
Visit Santa Clara
Popular places to visit
Multiplaza Pacific Mall
During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
Avenida Balboa
You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.
Amador Causeway
You can learn about the history of Ancon with a stop at Amador Causeway. Stroll along the seaside or visit the shops in this vibrant area.
Cinta Costera
Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.
Uruguay Street
During your visit to Panama City, you can do some window-shopping at Uruguay Street. While in this family-friendly area, you can savor the top-notch restaurants.
Calle 50
You can find out about the history of Panama City with a trip to Calle 50. Discover the area's casinos, or seek out its local tours.
Santa Clara Hotel Deals
Hotel Riu Plaza Panama
The breakfast
Reviewed on Feb 2, 2026
Crowne Plaza Panama Airport by IHG
Amenities, clean
Reviewed on Feb 2, 2026
Waldorf Astoria Panama
Staff was super nice and room was great we also ate on the rooftop and food was great!
Reviewed on Feb 3, 2026
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
All fantastic. We return year after year
Reviewed on Feb 2, 2026
Sheraton Grand Panama
Great staff
Reviewed on Jan 15, 2026
The Executive Hotel
Staff was great, rooms were ok and clean. Breakfast was good, coffee fresh and hot at anytime so overall excellent stay. Did advertise an airport shuttle which was not available, but taxis @ 30 were available.
Reviewed on Feb 5, 2026
Other neighborhoods around Santa Clara
Juan Diaz
You'll enjoy the restaurants and shopping in Juan Diaz. You might want to make time for a stop at Los Pueblos Commercial Center or Estadio Rommel Fernandez.
Costa del Este
Travelers like the restaurants in Costa del Este, and Atrio Mall is a top attraction you might want to visit.
Parque Lefevre
You'll enjoy the restaurants and museums in Parque Lefevre. You might want to make time for a stop at Panama Viejo or National Craft Market.
San Francisco
San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.
Don Bosco
If you're looking for some top things to see and do in Don Bosco and surrounding area, you can visit Los Pueblos Commercial Center and Metromall Panama.
Bethania
When in Bethania, you can plan a visit to El Dorado Mall and Panama Canal Murals, some noteworthy sights in the nearby area.
