San Francisco

Panama City

The Bridge of the Americas in summer, Panama City
This great beach is not far from the Royal Decameron Panama - and it is usually deserted!
La entrada a la Ciudad de Panamá
Edificio el tornillo
Rainy day in Panama City but the charm of this city never ends. A beautiful rainbow over the city invites us to spend a bright day in paradise. #LifeAtExpedia

Popular places to visit


San Francisco Hotel Deals

Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
The price is ₩201,660 per night from Apr 4 to Apr 5
₩201,660
₩221,826 total
Apr 4 - Apr 5
includes taxes & fees
Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,000 reviews)
Breakfast was great , clean room and staff was nice

Reviewed on Mar 20, 2026

Sheraton Grand Panama
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

4 out of 5
Via Israel y Calle 71, San Francisco Panama City Panama
The price is ₩130,927 per night from Mar 28 to Mar 29
₩130,927
₩144,023 total
Mar 28 - Mar 29
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,156 reviews)
The room was well designed and clean. There was a coffee pot for pre morning coffee. The free breakfast buffet was amazing and the restaurant was good. There is NO airport shuttle to or from the hotel. You must pay for this separately. Uber is an excellent option as a taxi can add up depending on ...

Reviewed on Mar 23, 2026

Ramada Plaza by Wyndham Panama Punta Pacifica
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica Panama City Panama
The price is ₩403,512 per night from Apr 9 to Apr 10
₩403,512
₩443,863 total
Apr 9 - Apr 10
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,001 reviews)
Fantastic pool. Great food, I'd recommend the fish and chips. Best I've ever had. Great bar. Friendly staff.

Reviewed on Mar 19, 2026

JW Marriott Panama
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
The price is ₩150,526 per night from Apr 18 to Apr 19
₩150,526
₩165,579 total
Apr 18 - Apr 19
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
9/10 Wonderful! (1,001 reviews)
Everything was awesome

Reviewed on Mar 24, 2026

Courtyard by Marriott Panama Multiplaza Mall
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
The price is ₩241,050 per night from Apr 10 to Apr 11
₩241,050
₩265,155 total
Apr 10 - Apr 11
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in ...
9/10 Wonderful! (1,002 reviews)
The hotel on a whole is very clean. I loved that everyday our towels were changed. Also, as you enter the hotel you can smell the freshness. I enjoyed the clean space every day.

Reviewed on Mar 20, 2026

Las Americas Golden Tower Panama
Aloft Panama

Aloft Panama

3.5 out of 5
Via Israel & Calle 76 Panama City Panama
The price is ₩176,792 per night from Apr 4 to Apr 5
₩176,792
₩194,471 total
Apr 4 - Apr 5
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a nightclub. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (999 reviews)
The property was amazing, staff was great,very clean, everyone was welcoming, food was good, need more variety for breakfast though

Reviewed on Mar 24, 2026

Aloft Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around San Francisco

Aerial cityscape skyline of Panama City

Obarrio

4/5(92 area reviews)

Unique features of Obarrio include the casinos and coffeehouses. Make a stop by Calle 50 or Soho City Center while you're exploring the area.

Obarrio
Panama, Panama City

Punta Pacifica

Notable for its seaside views, restaurants, and casinos, Punta Pacifica is a sought-after destination for many travelers visiting Panama City. If you want to see some sights in the area, check out Pacific Center or Avenida Balboa.

Punta Pacifica
 sunset sky above Panama City -  cityscape panorama view

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Pacific Center while you're in town.

Punta Paitilla
Summer time in Panama City, blue sky and sunny days to enjoy this city. #lifeatexpedia #PanamaCity #travel

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

Bella Vista
Aerial view of the city skyline of Panama City business district

Campo Alegre

4/5(369 area reviews)

If you're spending some time in Campo Alegre, Uruguay Street and Calle 50 are top sights worth seeing.

Campo Alegre
Old and traditional Yatch Club at Cinta Costera, Panama City, Panama.

Marbella

5/5(2 area reviews)

You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera.

Marbella


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