The Best Hotels Closest to Santa Fe Depot Museum in Gainesville for 2026

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Our top choices for Santa Fe Depot Museum hotels

A two-story house with a swimming pool, outdoor furniture, and a well-maintained garden.

A beach with a sunset, waves, and a few trees and structures in the distance.

A wooden deck with a hot tub, outdoor furniture, and a welcome sign on a building.

A golf course with a pond, a clubhouse, and a parking area.

1. The Lancaster Manor B&B

0.8 km from Santa Fe Depot Museum

Jeffrey

₩278,447

₩320,215 total

includes taxes & fees

Oct 13 - Oct 14

A modern hotel lobby with a wooden ceiling, a large TV, a sofa, a coffee table, and a patterned floor.

A hotel with a modern facade, a covered entrance, and a parking lot.

A modern hotel lobby with a wooden ceiling, a reception desk, a seating area with green sofas, and a visible kitchen in the background.

A spacious indoor area with a curved ceiling, a central bar area, multiple seating arrangements, and a large table in the foreground.

2. Fairfield Inn & Suites by Marriott Gainesville I-35

1.8 km from Santa Fe Depot Museum

Lori

₩128,558

₩147,841 total

includes taxes & fees

Oct 18 - Oct 19

A buffet with labeled containers of omelets and other dishes.

A Holiday Inn Express hotel with a covered entrance, multiple windows, and a brick facade.

A hotel room with a bed, a desk, a chair, a sofa, and a ceiling fan.

A lobby with a coffee table, armchairs, a sofa, and lamps.

3. Holiday Inn Express Hotel & Suites Gainesville by IHG

1.1 km from Santa Fe Depot Museum

Miguel

₩105,881

₩121,763 total

includes taxes & fees

Nov 10 - Nov 11

A modern hotel room with a large bed, a desk, a chair, and a sofa.

A gym with treadmills, elliptical machines, and weight machines.

A motel with a covered parking area and multiple cars parked.

A reception area with a Days Inn sign, a counter with a tiled backsplash, a television, and a coffee machine.

4. Days Inn by Wyndham Gainesville

2.5 km from Santa Fe Depot Museum

Tina

₩96,499

₩110,974 total

includes taxes & fees

Nov 1 - Nov 2

A spacious living area with a sofa, a glass-top coffee table, a desk with a computer, and a magazine rack. There is a dining area with tables and chairs in the background.

A hotel hallway with carpeted floors, doors on both sides, and a ceiling with recessed lighting.

A hotel room with two beds, a desk, a chair, a TV, and a large window with curtains.

A vending machine with various drinks and snacks, a push door, and a digital display.

5. Super 8 by Wyndham Gainesville TX

2.7 km from Santa Fe Depot Museum

Sid

₩83,230

₩95,721 total

includes taxes & fees

Oct 14 - Oct 15

A large indoor swimming pool with clear views through tall windows, a lounge chair, and a table with chairs.

A room with a blue sofa, a small ottoman, a lamp, and a window with curtains.

A hotel room with a large bed, wooden headboard, bedside tables, a desk with a chair, and a television.

A reception desk with a sign reading "Comfort Suites." There are two digital kiosks and a reception counter.

6. Comfort Suites Gainesville

2.5 km from Santa Fe Depot Museum

Tammera

₩95,292

₩109,587 total

includes taxes & fees

Oct 18 - Oct 19

A kitchen with a countertop, a refrigerator, a ceiling fan, and a window.

A bedroom with a bed, a desk, a chair, an air conditioning unit, a door, and a window.

A motel with a brick facade, a covered parking area, and a car parked in front.

A hotel room with a desk, a television on a stand, a mirror, and a small cabinet.

7. Budget Host Motel Gainesville

2.7 km from Santa Fe Depot Museum

Mark

₩80,416

₩92,478 total

includes taxes & fees

Oct 12 - Oct 13

A spacious living area with a stone accent wall, a brown sofa, and a kitchen in the background.

A long corridor with a dining area featuring tables and chairs, a kitchen area, and a reception desk.

A hotel room with two beds, a desk with a TV, a mirror, and a lamp.

A laundry area with two washing machines and a dryer, a water fountain, and a sign indicating guest laundry hours.

8. Loyalty Inn Gainesville

3 km from Santa Fe Depot Museum

Jimmy

₩62,657

₩72,066 total

includes taxes & fees

Oct 14 - Oct 15

A hotel room with two beds, a desk with a chair, a television, and a minibar.

A modern lobby with a green leather sofa, a glass coffee table, and potted plants.

A breakfast bar with coffee machines, a refrigerator, and a seating area with a wooden table and chairs.

9. Quality Inn Gainesville

0.9 km from Santa Fe Depot Museum

Roxann

₩73,714

₩85,775 total

includes taxes & fees

Oct 12 - Oct 13

A hotel room with a bed, a desk with a computer, a TV, a microwave, and a refrigerator.

Two refrigerated beverage dispensers labeled 'CHILLED' and 'FROZEN' with various drinks inside.

A modern lobby with a green sofa, blue armchairs, a glass coffee table, and potted plants.

A spacious dining area with multiple wooden tables and chairs, a counter with food service equipment, and large windows with blinds.

10. Suburban Studios Gainesville

0.9 km from Santa Fe Depot Museum

Lynzee

₩66,343

₩76,296 total

includes taxes & fees

Oct 18 - Oct 19

A spacious living room with patterned sofas, a coffee table, and a flat-screen TV mounted on the wall.

A reception area with a curved reception desk, a flat-screen TV mounted on the wall, and framed artwork above the desk.

A Best Western hotel with a brick facade, a covered entrance, and stone pillars.

A modern kitchen with a large island, bar stools, and a flat-screen TV.

11. Best Western Red River Inn & Suites

13.9 km from Santa Fe Depot Museum

Douglas

₩128,652

₩144,091 total

includes taxes & fees

Oct 27 - Oct 28

A spacious kitchen with checkered flooring, wooden cabinets, and various appliances.

A gym with treadmills, elliptical machines, and a weight bench.

A laundry area with a wall-mounted soap, bleach, and softener dispenser, a washing machine, and stacked dryers.

A kitchen with wooden cabinets, a refrigerator, and a tiled floor.

12. Hampton Inn & Suites Gainesville

6.4 km from Santa Fe Depot Museum

Charlie

₩104,406

₩120,548 total

includes taxes & fees

Nov 9 - Nov 10

A rustic interior with wooden floors, hanging plants, and a rustic ceiling.

A rustic dining area with a stone fireplace, wooden ceiling, and a table set for dining.

An outdoor seating area with wooden chairs and tables, surrounded by trees and string lights.

A backyard with a swimming pool, a wooden pergola, and a stone patio.

13. Oak Meadow Ranch

15 km from Santa Fe Depot Museum

Isaac

₩205,060

₩301,881 total

includes taxes & fees

Oct 14 - Oct 15

A spacious lobby with a reception desk, a staircase, and seating area.

A spacious lobby with a fireplace, patterned wallpaper, and modern seating arrangements.

A hotel room with a large bed, two bedside lamps, a bathroom with a bathtub, and a large mirror.

A swimming pool with a metal railing, surrounded by lounge chairs and a door in the background.

14. La Quinta Inn & Suites by Wyndham Gainesville

5.7 km from Santa Fe Depot Museum

Teresa

₩113,922

₩133,638 total

includes taxes & fees

Nov 2 - Nov 3

A hotel room with two beds, each with a green headboard, white bedding, and red accents. There are abstract paintings on the wall above the beds.

A building with a sign reading "Lindsay Inn" and a covered entrance area with columns.

A bathroom with a toilet, a shower curtain, a towel rack with towels, and a toilet paper holder.

A compact kitchen area with a microwave and a black dishwasher.

15. Lindsay Inn

7.9 km from Santa Fe Depot Museum

Tammera

₩93,818

₩105,076 total

includes taxes & fees

Oct 12 - Oct 13

A hotel room with a bed, bedside table, lamp, and a television on a dresser.

A spacious lobby with a ceiling fan, a reception desk, a refrigerator, and a door leading to the outside.

A building with a covered entrance, a clock, and a sign with a flag.

A hotel room with a bed, bedside lamps, a telephone, a nightstand, a window with curtains, and a door.

16. OYO Hotel Valley View TX, I-35

16.5 km from Santa Fe Depot Museum

Brian

₩81,823

₩96,550 total

includes taxes & fees

Oct 25 - Oct 26

A modern living room with a fireplace, two bean bag chairs, a television, and large windows with blinds.

A modern hotel lobby with dark wood flooring, comfortable seating, a flat-screen TV, and a reception desk.

A living room with a sofa, two bean bags, a coffee table, and a TV mounted on the wall.

A modern restaurant with a bar area, dark wooden flooring, and contemporary furniture.

17. Red River Inn And Suites

13.9 km from Santa Fe Depot Museum

Troy

₩132,686

₩148,608 total

includes taxes & fees

Oct 12 - Oct 13

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Compare popular hotels close to Santa Fe Depot Museum

Property	Property class	Guest rating
The Lancaster Manor B&B	10.0 Exceptional 115 reviews	View
Fairfield Inn & Suites by Marriott Gainesville I-35	8.6 Excellent 1,001 reviews	View
Holiday Inn Express Hotel & Suites Gainesville by IHG	7.8 Good 1,000 reviews	View
Days Inn by Wyndham Gainesville	7.8 Good 1,003 reviews	View
Super 8 by Wyndham Gainesville TX	7.2 Good 1,000 reviews	View

Top Santa Fe Depot Museum Hotel Reviews

Oak Meadow Ranch

10/10 Excellent

"Amazing adventure! Book the Tranquility Cabin and the Serenity Slot experience! We’re still on a high from this experience! It was an absolutely amazing adventure that exceeded every single one of our expectations. The entire process was seamless and incredibly well-organized. The guides/hosts were phenomenally knowledgeable, patient, and full of infectious energy that made the day even more special. It balanced pure excitement with wonderful hospitality, leaving both of us completely captivated. It was genuinely a life-disrupting, beautiful memory that we will treasure forever. Don't even hesitate—just book it! For us, we’re looking forward to arranging to bring more family with us next time for a possible giraffe adventure! Thank you again Oak Meadow Ranch for such a one-a-lifetime adventure!"

Holiday Inn Express Hotel & Suites Gainesville by IHG

10/10 Excellent

"Very clean property….also very convenient location."

Super 8 by Wyndham Gainesville TX

10/10 Excellent

"This is an older property but for the most part is nice, we felt safe. Really like the big fridge it kept our drinks very cold better than most motels. Only thing is all the road construction around the area. If you’re bougie this probably won’t be the place for you."

OYO Hotel Valley View TX, I-35

10/10 Excellent

"Staff"

The Lancaster Manor B&B

10/10 Excellent

"You will not find a better couple to host you and you will not find a place with more character than this mansion. Everything was perfect from the check in to the food. We will be back!"

Budget Host Motel Gainesville

10/10 Excellent

"Every\nThing was excellent, clean room.Good parking , good air conditioner , nice staff"

Victorian Inns By OYO Whitesboro U.S. Hwy 82

10/10 Excellent

"Passing thru and needed a place to crash for the night! It was clean and beds were comfy! And price was great!"

Other attractions near Santa Fe Depot Museum

Cooke County Courthouse

7.6/10 (89 reviews)

After visiting Cooke County Courthouse, make a plan to see the other sights and activities in Gainesville. While you're in the area, find time to visit its casinos.

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Depot Park

Depot Park is just one of the places to see in Gainesville, so why not enjoy the other things to explore during your travels? While in this family-friendly area, find time to visit its casinos.

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Butterfield Stage Players

7.2/10 (64 reviews)

You can get tickets for a performance at Butterfield Stage Players during your trip to Gainesville. While you're in the area, find time to visit its casinos.

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State Theater

7.4/10 (54 reviews)

You can make plans for a show at State Theater during your stay in Gainesville. While you're in the area, find time to visit its casinos.

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Morton Museum

7.2/10 (68 reviews)

You can spend time browsing the exhibits at Morton Museum during your travels in Gainesville. While you're in the area, find time to visit its casinos.

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Tom Thumb Park

After visiting Tom Thumb Park, make a plan to see the other sights and activities in Gainesville. While in this family-friendly area, find time to visit its casinos.

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Jaycee Park

After visiting Jaycee Park, make a plan to see the other sights and activities in Gainesville. While in this family-friendly area, find time to visit its casinos.

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Gainesville War Memorial

8.0/10 (109 reviews)

Find out about the history of Gainesville when you take a trip to Gainesville War Memorial. While you're in the area, find time to visit its casinos.

See properties

Frequently asked questions

What's the area like around Santa Fe Depot Museum?

Santa Fe Depot Museum is located in a welcoming area of Gainesville known for its top-notch casinos. If you're looking for a convenient place to stay, check out the 17 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Santa Fe Depot Museum?

Quality Inn Gainesville is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located just a short 0.5 mi (0.9 km) from Santa Fe Depot Museum. Other good options within a short distance include Suburban Studios Gainesville and Holiday Inn Express Hotel & Suites Gainesville by IHG.

How many hotels should I expect to find near Santa Fe Depot Museum?

Expedia has 17 hotels and other accommodations within a mile from Santa Fe Depot Museum.

If I need to cancel the hotel reservation for my stay near Santa Fe Depot Museum, will I receive a refund?

Yes, most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to get the best deals near Santa Fe Depot Museum.

Where can I learn more about changing or cancelling my trip in the area near Santa Fe Depot Museum?

To find more details about picking new dates or cancelling your stay near Santa Fe Depot Museum, head over to our customer service page.

What can I see and do near Santa Fe Depot Museum?

You can enjoy live performances at Butterfield Stage Players and State Theater. Get outside and spend some time strolling around Leonard Park, Tom Thumb Park, and Jaycee Park. Gainesville War Memorial and Frank Buck Zoo are both worth a visit while you're checking out the area.

Find hotels near Santa Fe Depot Museum, Gainesville from ₩72,066

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Our top choices for Santa Fe Depot Museum hotels

1. The Lancaster Manor B&B

2. Fairfield Inn & Suites by Marriott Gainesville I-35

3. Holiday Inn Express Hotel & Suites Gainesville by IHG

4. Days Inn by Wyndham Gainesville

5. Super 8 by Wyndham Gainesville TX

6. Comfort Suites Gainesville

7. Budget Host Motel Gainesville

8. Loyalty Inn Gainesville

9. Quality Inn Gainesville

10. Suburban Studios Gainesville

11. Best Western Red River Inn & Suites

12. Hampton Inn & Suites Gainesville

13. Oak Meadow Ranch

14. La Quinta Inn & Suites by Wyndham Gainesville

15. Lindsay Inn

16. OYO Hotel Valley View TX, I-35

17. Red River Inn And Suites

Compare popular hotels close to Santa Fe Depot Museum

Top Santa Fe Depot Museum Hotel Reviews

Oak Meadow Ranch

Holiday Inn Express Hotel & Suites Gainesville by IHG

Super 8 by Wyndham Gainesville TX

OYO Hotel Valley View TX, I-35

The Lancaster Manor B&B

Budget Host Motel Gainesville

Victorian Inns By OYO Whitesboro U.S. Hwy 82

Other attractions near Santa Fe Depot Museum

Cooke County Courthouse

Depot Park

Butterfield Stage Players

State Theater

Morton Museum

Tom Thumb Park

Jaycee Park

Gainesville War Memorial

Frequently asked questions