Find hotels in Santa Lucia, Syracuse from ₩74,463
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Go beyond your typical stay in Santa Lucia
Farm
Family friendly
Check prices for these dates
Discover 3,843 Santa Lucia hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.
Our top choices for Santa Lucia hotels

Grande Albergo Alfeo
Grande Albergo Alfeo
8.6 out of 10, Excellent, (638)
The price is ₩186,150
₩228,454 total
includes taxes & fees
Sep 7 - Sep 8

Hotel Palazzo Cavalieri
Hotel Palazzo Cavalieri
8.8 out of 10, Excellent, (31)
The price is ₩261,066
₩297,622 total
includes taxes & fees
Sep 20 - Sep 21

Caportigia Boutique Hotel
Caportigia Boutique Hotel
9.4 out of 10, Exceptional, (241)
The price is ₩313,220
₩360,794 total
includes taxes & fees
Sep 26 - Sep 27

Lakkios
Lakkios
9.0 out of 10, Wonderful, (53)
The price is ₩126,322
₩160,260 total
includes taxes & fees
Sep 29 - Sep 30

B&B Nike
B&B Nike
9.0 out of 10, Wonderful, (69)
The price is ₩116,794
₩133,137 total
includes taxes & fees
Sep 15 - Sep 16

Fortaleza Charme House
Fortaleza Charme House
10.0 out of 10, Exceptional, (21)
The price is ₩248,212
₩282,963 total
includes taxes & fees
Sep 7 - Sep 8
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Where to stay in Santa Lucia
Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most.

Ortigia
1 out of top 10 points of interest in this area
Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.
Grottasanta
Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.
Acradina
You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.
Neapolis
While visiting Neapolis, you might make a stop by sights like Ear of Dionysius and Roman Amphitheatre of Syracuse.
Tiche
Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.
Top Santa Lucia Hotel Reviews
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Hotels in top Syracuse neighborhoods
Hotels Close to Nearby Airports
More ways to book
Expedia's Latest Trends
Hotels
Flights
Packages