Santa Lucia Vacations

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  • Better together

    Save up to ₩1,660,000 when you book a flight and hotel together*

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    With over 300,000 hotels worldwide, it's easy to create a perfect package

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    Plan, book, and manage your trip all in one place

Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most. Learn more about Santa Lucia
Ancient ruins with stone columns and a building with green shutters in the background.

Ortigia

4 out of top 10 points of interest in this area

Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.

Find hotels in Ortigia

Santa Lucia Hotel Deals

Grande Albergo Alfeo

Grande Albergo Alfeo

4 out of 5
Via Nino Bixio 5 Syracuse SR
Fully refundableReserve now, pay when you stay
The price is ₩113,881 per night from Nov 15 to Nov 16
₩113,881
₩129,824 total
Nov 15 - Nov 16
includes taxes & fees
8.6/10 Excellent! (711 reviews)
"Very noisy on the weekends. Restaurants and bars across the road were lively until 4:00 am. Hotels is tired looking."

Reviewed on Oct 20, 2026

Grande Albergo Alfeo
Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri

4 out of 5
42 Via Malta Syracuse SR
Fully refundableReserve now, pay when you stay
The price is ₩109,264 per night from Nov 19 to Nov 20
₩109,264
₩124,568 total
Nov 19 - Nov 20
includes taxes & fees
Hotel Palazzo Cavalieri
Nostos rooms & Apartments

Nostos rooms & Apartments

3 out of 5
Corso Umberto I, 66 Syracuse SR
Fully refundableReserve now, pay when you stay
The price is ₩81,199 per night from Nov 17 to Nov 18
₩81,199
₩92,564 total
Nov 17 - Nov 18
includes taxes & fees
9.2/10 Wonderful! (299 reviews)
"Very good situation between Ortigia and Syracuse, no car needed. Modern and clean."

Reviewed on Oct 26, 2026

Nostos rooms & Apartments
See all 3,745 properties in Santa Lucia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Lucia vacation package cost?
Our Santa Lucia packages, which start from just , are the perfect way to save loads of cash. All you have to do is choose your preferred flights, hotels and rental cars to create your ideal escape.
How do I get a cheap travel package to Santa Lucia?
Combine your hotels and flights, throw in extras such as a rental car or activities, and save with a Santa Lucia vacation package. You won't just score big discounts on your escape — you'll have lots of choice at your fingertips too. When you book with Expedia, you can choose from more than 550 airlines and 1,000,000 hotels all over the world. Your affordable vacation begins right here, right now!
Where should I stay in Santa Lucia?
Take the hassle out of sightseeing by staying in a hotel right around the corner from Santa Lucia's iconic attractions. Cathedral of Syracuse and Temple of Apollo are two visitor favorites.
What are the top hotels in Santa Lucia?
If this will be your first time in Santa Lucia, book a room at Hotel Cavalieri or Paolanna Luxury Rooms. Both hotels offer friendly service and are popular options with many travelers.
How far in advance should I book my Santa Lucia vacation?
Smart travelers will likely want to reserve their seats early. You can normally compare international fares on Expedia up to 12 months before your flight. If you're purchasing tickets last minute, don't stress. Budget prices occasionally appear in the last weeks prior to departure.
What does an Expedia Santa Lucia travel package include?
Packages include hotels, flights and rental cars, but you can mix and match them to create your ideal Santa Lucia vacation. You can also add on some activities and experiences once you've made your booking. You're in charge! When you bundle your bookings with Expedia, you'll score discounts you won't find anywhere else.
What should I know before booking a Santa Lucia travel package?
You'll land impressive savings when you bundle your hotels, flights and rental cars into a package. Plus, booking everything in one place will make your trip planning easier. So why waste money or time? Whether you're putting together a ritzy romantic getaway or a budget family adventure, browse our package deals today.
Can I choose my airline with a Santa Lucia Expedia vacation package?
You can, and with more than 550 airlines to pick from globally, you have plenty of choice. Search the available options and find out which airline best fits your needs and budget.
If I'm not able to travel, can I cancel my Santa Lucia vacation package?
Yes, you can. We realize life doesn't always go to plan, so we're here to help if you have to make changes to your Santa Lucia vacation package. It may be possible to cancel or amend your itinerary at no cost if you've booked in the last 24 hours. Your airline, hotel or car rental company may charge you a fee if your booking was made more than 24 hours ago. Visit our Customer Service Portal for further information. Also, check your itinerary for the nitty-gritty on change fees.

Stay near popular Santa Lucia attractions

Porto Piccolo

8.8/10 (189 reviews)
Explore the waterfront in Syracuse with a trip to Porto Piccolo. Wander the seaside in this culturally rich area.
See properties
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.