Top Santa Lucia Hotels

A modern building with a unique triangular roof and a central spire.

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Compare popular hotels in Santa Lucia

Property	Property class	Guest rating
Giuggiulena Villa	3.0 star property	10.0 Exceptional 132 reviews	View
Calafatari B&B	3.0 star property	9.8 Exceptional 18 reviews	View
Caportigia Boutique Hotel	5.0 star property	9.4 Exceptional 299 reviews	View
Lakkios	3.0 star property	9.2 Wonderful 80 reviews	View
Hotel Palazzo Cavalieri	4.0 star property	9.0 Wonderful 47 reviews	View

Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most.

A historic waterfront with a stone bridge, illuminated buildings, and a calm water body.

Ortigia

Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.

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A natural rock arch over a body of water with people paddling in kayaks.

Grottasanta

Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

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Ancient ruins with a large amphitheater surrounded by trees.

Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

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An ancient amphitheater with stone ruins and a grassy field.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.

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An aerial view of a coastal city with a prominent fortified structure and a densely built urban area in the background.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

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Top Santa Lucia Hotel Reviews

Lanterne Magiche Ortigia

10/10 Excellent

"This is a great spot in Ortigia. The room was spacious with a nice kitchenette. The room was clean, the bed was very comfy. We had a room with a small ocean view. Up one floor is a wonderful rooftop deck to hang out on and relax. The building is a very old one and has a small movie theatre inside. The breakfast is great, local foods and lots of choices with excellent cappuccino!"

Maniace Boutique Hotel Ortigia UNA Esperienze

10/10 Excellent

"We arrived feeling stressed after the drive to the hotel! The lovely young lady on the front desk welcomed us with a warm Smile and arranged for the bartender to bring us a drink outside so we could soak up the afternoon sun and relax. We were served a delicious aperol. The decor throughout the hotel is very tasteful even the corridors to the room. Clean white walls but a hint of original brickwork showing. Comfy beds, crisp white linen. Lovely toiletries in the bathroom. Everywhere was spotless. Great breakfast and amazing service. Lovely location just opposite the pretty pebbly beach and around the corner from the lovely streets full of restaurants, shops and wonderful architecture. Would definitely return."

Grand Hotel Villa Politi

8/10 Good

"We overall really enjoyed our 3 night stay here, and appreciated the quiet and historic charm of this hotel. It is an incredibly unique peace of property, with an attached historic Latomie that was both beautiful and intriguing—we really wished the hotel had access to explore the areas below. We also really appreciated the continental breakfast, and were surprised by other’s complaints in reviews we had read before staying here. It was the most elaborate continental breakfast we have ever experienced, with options ranging from fresh fruit, to delicious pastries, and even eggs and bacon for those with used to a more American meal. We loved the pool as well, however we were disappointed that it was only open until 7pm every day, we would have enjoyed an evening swim. The bar was also closed, though they provided service through the bar inside. We also really enjoyed the 2 for $22 aperitivo offered from the bar. The room we stayed in was small and a bit dated, but met our expectations for an older hotel. We also had issues with the AC not turning off and making our room very cold. We were able to find parking every night, however I would not describe it as a big parking lot, and it was overflowing every night with people crammed wherever they could find room."

B&B Nike

10/10 Excellent

"Brilliant apartment in a good location for both transport links and sightseeing, easy walking distance of Ortigia as well as the train station and bus links. Lovely large room with balcony and check in information all communicated well from the owners. There are number of good cafes, bars and restaurants nearby if you would prefer to eat close by. Would highly recommend this property."

Algila' Ortigia Charme Hotel

10/10 Excellent

"Beautiful hotel with wonderful hospitality We absolutely loved our stay at Hotel Algilà Ortigia Charme. From the moment we arrived, the staff were warm, friendly and genuinely welcoming. The hotel is full of Sicilian character and charm, and its location in Ortigia was perfect for exploring on foot. Our room was comfortable and beautifully suited to the character of the hotel, and the staff were always happy to help with recommendations and anything we needed. After travelling throughout Sicily for two weeks, what stood out most was the genuine hospitality. We felt like valued guests, not just another reservation. Algilà was exactly what we hoped for from a Sicilian hotel — charming, personal and welcoming. We would happily stay here again and highly recommend it to anyone visiting Ortigia!"

Frequently asked questions

What is Santa Lucia like?

Santa Lucia is a neighborhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Be sure to check out Porto Piccolo and Ionian Sea while you're in the neighborhood.

Where is the best place to stay in Santa Lucia?

Based on our traveler data, Grande Albergo Alfeo is one of the top choices for your stay in Santa Lucia. This hotel offers free breakfast and a restaurant. Other good choices for your stay in the area include Nostos rooms & Apartments and Caportigia Boutique Hotel.

How many hotels can I expect to find in Santa Lucia?

Expedia has 313 hotels and other accommodations in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.

If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get the best options available in Santa Lucia.

Where can I learn more about changing or cancelling my trip to Santa Lucia?

For more details about changing or cancelling your trip to Santa Lucia, click here.

What are the top things to see and do in Santa Lucia?

Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops to visit in the neighborhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica, and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.

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Our top choices for Santa Lucia hotels

1. Grande Albergo Alfeo

2. Caportigia Boutique Hotel

3. Nostos rooms & Apartments

4. Fortaleza Charme House

5. Hotel Palazzo Cavalieri

6. Melody rooms

7. Re Dionisio Luxury Suites

8. Lakkios

9. B&B Nike

10. Casa Miranda Boutique

11. Giuggiulena Villa

12. Calafatari B&B

13. San Nicola Rooms Siracusa

14. Piccolo Hotel Casa Mia

15. Residence Agatocle

16. Fortuna Guest House

17. Gymnasium

18. B&B IL MORO

19. Syraka Design Rooms & Suites

20. B&B Siracusa

Compare popular hotels in Santa Lucia

Where to stay in Santa Lucia

Ortigia

Grottasanta

Neapolis

Tiche

Acradina

Top Santa Lucia Hotel Reviews

Lanterne Magiche Ortigia

Frequently asked questions

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