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Our top choices for Santa Lucia hotels

Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (267 reviews)
"Valentina & Malvina"
United States
Andrew
The price is ₩176,280
₩211,144 total
includes taxes & fees
Mar 9 - Mar 10
Caportigia Boutique Hotel

Grande Albergo Alfeo

Grande Albergo Alfeo
4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (654 reviews)
"Good front desk staff, welcoming breakfast staff, clean room and good area for walking to attractions. "
Canada
Reita
The price is ₩136,512
₩155,627 total
includes taxes & fees
Mar 31 - Apr 1
Grande Albergo Alfeo

Gymnasium

Gymnasium
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (40 reviews)
"Nice kitchen area, centrally located."
United States
Richard
Gymnasium

Lakkios

Lakkios
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (64 reviews)
"Nice, central, clean, easy to park, quiet during the night, staff was welcoming, nice breakfast with view - excellent choice!"
Norway
Jon-Kåre
Lakkios

Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia
3.0 star property
Santa Lucia
8.6 out of 10, Excellent, (375 reviews)
"The staff is extremely nice and friendly and you feel welcome. "
Canada
Florentina
Piccolo Hotel Casa Mia

Nostos rooms & Apartments

Nostos rooms & Apartments
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (274 reviews)
"Welcoming, room, staff and area around definitely stood out!"
Canada
Aina
The price is ₩91,663
₩104,504 total
includes taxes & fees
Mar 10 - Mar 11
Nostos rooms & Apartments

Fortaleza Charme House

Fortaleza Charme House
Santa Lucia
10.0 out of 10, Exceptional, (27 reviews)
"Wonderful stay in the center of it all "
United States
lori
The price is ₩228,450
₩260,423 total
includes taxes & fees
Mar 11 - Mar 12
Fortaleza Charme House

Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri
4.0 star property
Santa Lucia
8.8 out of 10, Excellent, (41 reviews)
"Good central location & nice breakfast selection "
Australia
Alan
Hotel Palazzo Cavalieri

Giuggiulena Villa

Giuggiulena Villa
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (126 reviews)
"Fantastic stay. Made to feel very welcome and what a lovely relaxing place to stay. Evening meal was exceptional. "
United States
Paul
The price is ₩350,305
₩399,348 total
includes taxes & fees
Mar 15 - Mar 16
Giuggiulena Villa

Hotel Le Muse

Hotel Le Muse
3.0 star property
Santa Lucia
7.4 out of 10, Good, (71 reviews)
"All was great"
United States
deanne
Hotel Le Muse

Calafatari B&B

Calafatari B&B
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (11 reviews)
"We had a lovely stay. Anna was very welcoming. We had a lovely large clean room and a nice modern bathroom. She went all out for breakfast. "
United States
Carl and Lina
Calafatari B&B

Re Dionisio Luxury Suites

Re Dionisio Luxury Suites
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (57 reviews)
"Spacious room, dated but comfortable."
United States
Kenneth
The price is ₩626,149
₩706,000 total
includes taxes & fees
Mar 9 - Mar 10
Re Dionisio Luxury Suites

B&B Nike

B&B Nike
Santa Lucia
8.8 out of 10, Excellent, (75 reviews)
"Clean, good location. "
United States
Salvatore
B&B Nike

Isonzo Suites

Isonzo Suites
Santa Lucia
8.4 out of 10, Very Good, (5 reviews)
"."
Italy
Gianluca
The price is ₩109,858
₩176,327 total
includes taxes & fees
Mar 15 - Mar 16
Isonzo Suites

B&B Siracusa

B&B Siracusa
Santa Lucia
9.0 out of 10, Wonderful, (59 reviews)
"Good location, very modern clean accommodation."
Canada
Malcolm
The price is ₩125,355
₩142,906 total
includes taxes & fees
Mar 14 - Mar 15
B&B Siracusa

AmaCasa Siracusa

AmaCasa Siracusa
Santa Lucia
10.0 out of 10, Exceptional, (1 review)
"Siamo stati molto bene, la struttura internamente è abbastanza ammodernata e l'accesso è stato"
Italy
Alessandro
The price is ₩141,025
₩160,764 total
includes taxes & fees
Mar 9 - Mar 10
AmaCasa Siracusa

Regina Margherita

Regina Margherita
Santa Lucia
7.8 out of 10, Good, (16 reviews)
"The area is so close to the Ortigia Island where the beautiful cathedral and Doumo are. Lovely walk around the entire island and areas to go in the water If you like. Many dining options and shopping too. Wonderful area!"
United States
Laura
Regina Margherita

San Nicola Rooms Siracusa

San Nicola Rooms Siracusa
Santa Lucia
9.2 out of 10, Wonderful, (5 reviews)
"Quarto bem decorado, um pouco apertado só tem lugar para uma mala. A reserva foi quarto de casal, mas nos colocaram em camas de solteiro, o problema era que o colchão escorregava. Eu reservei locais com elevador, muito antigo e tinha que subir com a mala por uns 10 degraus até o elevador.a equipe simpática e atenciosa, o café da manhã simples, mas de qualidade. Muito bonita a decoração dos espaços. A localização pelo app da expedia mostra outro endereço. Tivemos dificuldade de encontrar a...
Brazil
Paula
The price is ₩162,969
₩185,781 total
includes taxes & fees
Mar 9 - Mar 10
San Nicola Rooms Siracusa

Agorà

Agorà
Santa Lucia
10.0 out of 10, Exceptional, (2 reviews)
"Trevligt, rent, bra service. Hade turen att få balkong. "
Sweden
Olof
The price is ₩144,158
₩164,347 total
includes taxes & fees
Mar 9 - Mar 10
Agorà

Hotel Mediterraneo

Hotel Mediterraneo
3.0 star property
Santa Lucia
7.8 out of 10, Good, (123 reviews)
"Very friendly and helpful staff."
United States
David
Hotel Mediterraneo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most.

Ortigia

Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.

Neapolis

While visiting Neapolis, you might make a stop by sights like Ear of Dionysius and Archaeological Park of Neapolis.

Grottasanta

Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Top Santa Lucia Hotel Reviews

Frequently asked questions

What is Santa Lucia like?
Santa Lucia is a neighborhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Be sure to check out Porto Piccolo and Ionian Sea while you're in the neighborhood.
Where is the best place to stay in Santa Lucia?
Based on Expedia customer reviews, Caportigia Boutique Hotel is the highest ranked property in Santa Lucia. This hotel offers a restaurant and free parking. Other top choices in the neighborhood include Lakkios and La casa di Aneupe.
How many hotels can I expect to find in Santa Lucia?
Expedia has 302 hotels and other accommodations in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get the best options available in Santa Lucia.
Where can I learn more about changing or cancelling my trip to Santa Lucia?
For more details about changing or cancelling your trip to Santa Lucia, click here.
What are the top things to see and do in Santa Lucia?
Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops to visit in the neighborhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica, and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.