Southern Illinois Vacations

Book a Hotel + Flight or Car together to unlock savings

Photo by Southernmost Illinois Tourism Bureau

  • Plan, book, travel with confidence

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    Better together
    Save up to ₩234,741 when you book a flight and hotel together*
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    Find the right fit
    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Rest easy
    Plan, book, and manage your trip all in one place

Where to stay in Southern Illinois

Find the best Southern Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southern Illinois
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Eastport

If you're spending some time in Eastport, Splash City Family Waterpark and Gateway Conference Center are top sights worth seeing.

Find hotels in Eastport

Find the Best Southern Illinois Vacation Packages

Southern Illinois Hotel Deals

Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. Vernon
3 out of 5
145 North 44th Street , Mount Vernon, IL
Fully refundableReserve now, pay when you stay
The price is ₩128,569 per night from Jul 27 to Jul 28
₩128,569
₩145,393 total
Jul 27 - Jul 28
includes taxes & fees
9.6/10 Exceptional! (1,369 reviews)
"Wow! What a great place. The room was exceptional. We didn’t use the bar or restaurant, but would definitely do so if we had been staying longer than overnight. Will be looking for Drury Inn whenever we travel."

Reviewed on Jun 30, 2025

Drury Plaza Hotel Mt. Vernon
Best Western Plus Pontoon Beach
Best Western Plus Pontoon Beach
3 out of 5
4 Regency Pkwy, Granite City, IL
Fully refundableReserve now, pay when you stay
The price is ₩127,892 per night from Jul 6 to Jul 7
₩127,892
₩141,935 total
Jul 6 - Jul 7
includes taxes & fees
8.4/10 Very Good! (681 reviews)
"Close parking, excellent staff, very accommodating of accessibility requests, quiet area."

Reviewed on Jun 30, 2025

Best Western Plus Pontoon Beach
Days Inn & Suites by Wyndham Caseyville
Days Inn & Suites by Wyndham Caseyville
2.5 out of 5
2423 Old Country Inn Drive, Caseyville, IL
Fully refundableReserve now, pay when you stay
The price is ₩71,871 per night from Jul 13 to Jul 14
₩71,871
₩81,117 total
Jul 13 - Jul 14
includes taxes & fees
3.8/10 (240 reviews)
"Maybe they need to repair the ice machine and bring back the snacks machines with card options. Maybe a convenient store inside. Repair the coin washer plus other things. But I still think it’s the best option to do the main things you do on a room: rest and be relaxed."

Reviewed on Jun 30, 2025

Days Inn & Suites by Wyndham Caseyville
See all 1,031 properties in Southern Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Southern Illinois vacation package cost?
From just , you can tailor make your Southern Illinois vacation package. Simply bundle hotels, flights and car rentals and be rewarded with discounts.
How do I get a cheap travel package to Southern Illinois?
Bundle your flights and hotels with Expedia to save big on your next big adventure. With over 550 airlines and 1,000,000 hotels globally, your Southern Illinois vacation package can be tailored exactly to suit your budget. With all that extra money, why not throw in one or more awesome activities and tours? It's an easy way to unlock even more discounts. Your dream getaway to Southern Illinois is much closer than you thought!
What are the top hotels in Southern Illinois?
Take a look at Super 8 by Wyndham Carbondale and Best Western Saluki Inn. They're top picks for lots of travelers to Carbondale. If Marion is on your travel itinerary, Super 8 by Wyndham Marion and Quality Inn And Suites are a couple of popular options.
How far in advance should I book my Southern Illinois vacation?
Reward yourself with the widest variety at the lowest prices by booking your vacation to Southern Illinois early. Air carriers usually sell flight tickets around 12 months before departure, so reserve your spot ASAP. That said, Expedia is dedicated to giving you the best bargains around, so it's never a bad time to book your dream vacation!
What does an Expedia Southern Illinois travel package include?
That depends on what sort of trip you're contemplating. Southern Illinois vacation deals can include flights, hotels and car rentals. You can mix and match to create the travel package that suits you. You can also add on experiences and activities after you've booked to get even bigger discounts.
What should I know before booking a Southern Illinois travel package?
You'll score excellent savings when you combine your flights, hotels and rental cars into a package. Not only that, booking everything in one spot will make your trip planning easier. So why waste your money or time? Whether you're organizing a ritzy city getaway or a low-cost family road trip, explore our vacation packages today.
Can I choose my airline with a Southern Illinois Expedia vacation package?
You can, and with more than 550 airlines to pick from across the globe, you're not short on choice. Browse the available options and see which airline fits your needs and budget.
If I'm not able to travel, can I cancel my Southern Illinois vacation package?
You can cancel your Southern Illinois booking if your plans have changed. Whether you'll be charged a fee or not depends on your airline, hotel or car rental company. It may be possible to cancel or change for free if you booked in the last 24 hours. Visit our Customer Service Portal to learn more.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.