Southwest Illinois Vacations

Book a Hotel + Flight or Car together to unlock savings

Photo by Southernmost Illinois Tourism Bureau

  • Plan, book, travel with confidence

  • Better together

    Save up to ₩1,660,000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Southwest Illinois

Find the best Southwest Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southwest Illinois
An aerial view of a city with a prominent river, a large bridge, and surrounding buildings.

Eastport

If you're spending some time in Eastport, Splash City Family Waterpark and Gateway Conference Center are top sights worth seeing.

Find hotels in Eastport

Find the Best Southwest Illinois Vacation Packages

Southwest Illinois Hotel Deals

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3.5 out of 5
145 North 44th Street  Mount Vernon IL
Fully refundableReserve now, pay when you stay
The price is ₩151,534 per night from Nov 15 to Nov 16
₩151,534
₩170,903 total
Nov 15 - Nov 16
includes taxes & fees
9.8/10 Exceptional! (1,868 reviews)
"Quiet clean rooms. Excellent breakfast before hitting the road!"

Reviewed on Nov 9, 2026

Drury Plaza Hotel Mt. Vernon
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

3 out of 5
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
The price is ₩122,862 per night from Nov 15 to Nov 16
₩122,862
₩138,809 total
Nov 15 - Nov 16
includes taxes & fees
Drury Inn & Suites St. Louis Fairview Heights
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

3 out of 5
1118 Central Park Drive O'Fallon IL
Fully refundableReserve now, pay when you stay
The price is ₩139,246 per night from Nov 15 to Nov 16
₩139,246
₩161,498 total
Nov 15 - Nov 16
includes taxes & fees
Drury Inn & Suites St. Louis O'Fallon, IL
See all 790 properties in Southwest Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Southwest Illinois attractions

O'Fallon Family Sports Park

8.6/10 (137 reviews)
Explore the great outdoors at O'Fallon Family Sports Park, a lovely green space in O'Fallon. Check out the shops and top-notch restaurants in this family-friendly area.
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Frequently asked questions

How much does a Southwest Illinois vacation package cost?
Explore the best of Southwest Illinois from just . Choose from a great selection of flights, rental cars and hotels to suit every budget and style. Land even more discounts when you add some experiences or tours to your package.
How do I get a cheap travel package to Southwest Illinois?
Search for flights that fit your busy schedule, add a hotel to your booking and see how much you save with a Southwest Illinois vacation package. It's as simple as that! From flights and hotels to rental cars and activities, Expedia makes traveling on the cheap easy. And with more than 550 partner airlines and 1,000,000 hotels all over the world to choose from, you'll never be short of choice.
What are the top hotels in Southwest Illinois?
Check out Super 8 by Wyndham Carbondale and Best Western Saluki Inn. They're top picks for many travelers headed to Carbondale. If Marion features in your travel plans, Super 8 by Wyndham Marion and Quality Inn And Suites are a couple of cozy options.
How far in advance should I book my Southwest Illinois vacation?
It can be hard to know exactly when is the ideal time to book your Southwest Illinois trip. But generally the earlier you book, the lower the prices. Sometimes, you can reserve your flights and hotels up to a year prior to departure. If you're thinking of a last-minute getaway, no need to panic! There are unbeatable bargains popping up on Expedia every single day.
What does an Expedia Southwest Illinois travel package include?
With Expedia, you can choose any combination of hotels, flights and car rentals to create your perfect Southwest Illinois package. Once you've made your booking, you can add on the fun things like tours and activities. Don't forget — the more you bundle, the more you'll save!
What should I know before booking a Southwest Illinois travel package?
Discover deals that match your budget with an Expedia package. Flights, hotels, rental cars — we have everything you need to plan your break. You'll save a tidy sum just by combining your bookings. Whether you're taking off on a winter adventure or venturing someplace warm, your ideal vacation is just clicks away.
Can I choose my airline with a Southwest Illinois Expedia vacation package?
You can, and with more than 550 airlines to pick from across the globe, you're not short on choice. Scroll through the available options and find out which airline fits your budget and needs.
If I'm not able to travel, can I cancel my Southwest Illinois vacation package?
If your vacation plans in Southwest Illinois have been upended, it's a relief to know that it's possible to amend or cancel your booking. If you booked less than 24 hours ago, you may be able to get a refund. If your booking was made more than 24 hours ago, your airline, hotel or car rental company may charge fees. To find out more, check our Customer Service Portal.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.