Southwest Illinois Vacations
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Where to stay in Southwest Illinois
Find the best Southwest Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southwest Illinois
Eastport
If you're spending some time in Eastport, Gateway Conference Center and Splash City Family Waterpark are top sights worth seeing.
Mulberry Hills
While Mulberry Hills isn't home to many top sights, Gateway Conference Center and FanDuel Sportsbook and Horse Racing are some notable places to visit nearby.
Uptown
If you're spending some time in Uptown, Kruta Bakery and World's Largest Catsup Bottle are top sights worth seeing.
Alorton
Alorton is well-liked for its restaurants. If you'd like to do some sightseeing in the greater East St. Louis area, you might plan a trip to Arsenal BG Ballpark or Gateway Arch.
Historic Downtown Collinsville
While Historic Downtown Collinsville isn't home to many top sights, Gateway Conference Center and Splash City Family Waterpark are some notable places to visit nearby.
Find the Best Southwest Illinois Vacation Packages
Southwest Illinois Hotel Deals
Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
₩120,654
₩136,316 total
Sep 27 - Sep 28
includes taxes & fees
9.2/10 Wonderful! (1,022 reviews)
"My son and I stayed here for a couple of days while I was in town visiting family over Labor Day weekend. The front desk person, Romello (sorry if I spelled your name wrong), was super nice and welcoming. All of the other staff we encountered throughout our stay were great as well. My son especially ..."
Reviewed on Sep 7, 2026
Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
₩148,810
₩167,832 total
Sep 20 - Sep 21
includes taxes & fees
9.8/10 Exceptional! (1,810 reviews)
"Every thing was good"
Reviewed on Sep 9, 2026
Quality Inn O'Fallon - St. Louis - Shiloh
1409 W US 50 O'Fallon IL
Fully refundable
₩89,884
₩103,349 total
Sep 17 - Sep 18
includes taxes & fees
7.4/10 Good! (1,008 reviews)
"Location great"
Reviewed on Sep 4, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Southwest Illinois attractions
World Wide Technology Raceway
9.0/10 (2 reviews)
Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
O'Fallon Family Sports Park
8.6/10 (137 reviews)
Explore the great outdoors at O'Fallon Family Sports Park, a lovely green space in O'Fallon. Check out the shops and top-notch restaurants in this family-friendly area.
DuQuoin State Fairgrounds
8.2/10 (95 reviews)
Catch an event at DuQuoin State Fairgrounds during your trip to Du Quoin. Experience the area's festivals and live music.
Frequently asked questions
How much does a Southwest Illinois vacation package cost?
Explore the best of Southwest Illinois from just . Choose from a great selection of flights, rental cars and hotels to suit every budget and style. Land even more discounts when you add some experiences or tours to your package.
How do I get a cheap travel package to Southwest Illinois?
Search for flights that fit your busy schedule, add a hotel to your booking and see how much you save with a Southwest Illinois vacation package. It's as simple as that! From flights and hotels to rental cars and activities, Expedia makes traveling on the cheap easy. And with more than 550 partner airlines and 1,000,000 hotels all over the world to choose from, you'll never be short of choice.
What are the top hotels in Southwest Illinois?
Check out Super 8 by Wyndham Carbondale and Best Western Saluki Inn. They're top picks for many travelers headed to Carbondale. If Marion features in your travel plans, Super 8 by Wyndham Marion and Quality Inn And Suites are a couple of cozy options.
How far in advance should I book my Southwest Illinois vacation?
It can be hard to know exactly when is the ideal time to book your Southwest Illinois trip. But generally the earlier you book, the lower the prices. Sometimes, you can reserve your flights and hotels up to a year prior to departure. If you're thinking of a last-minute getaway, no need to panic! There are unbeatable bargains popping up on Expedia every single day.
What does an Expedia Southwest Illinois travel package include?
With Expedia, you can choose any combination of hotels, flights and car rentals to create your perfect Southwest Illinois package. Once you've made your booking, you can add on the fun things like tours and activities. Don't forget — the more you bundle, the more you'll save!
What should I know before booking a Southwest Illinois travel package?
Discover deals that match your budget with an Expedia package. Flights, hotels, rental cars — we have everything you need to plan your break. You'll save a tidy sum just by combining your bookings. Whether you're taking off on a winter adventure or venturing someplace warm, your ideal vacation is just clicks away.
Can I choose my airline with a Southwest Illinois Expedia vacation package?
You can, and with more than 550 airlines to pick from across the globe, you're not short on choice. Scroll through the available options and find out which airline fits your budget and needs.
If I'm not able to travel, can I cancel my Southwest Illinois vacation package?
If your vacation plans in Southwest Illinois have been upended, it's a relief to know that it's possible to amend or cancel your booking. If you booked less than 24 hours ago, you may be able to get a refund. If your booking was made more than 24 hours ago, your airline, hotel or car rental company may charge fees. To find out more, check our Customer Service Portal.
Explore a world of travel with Expedia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
