Midtown, MO
St. Louis





Popular places to visit

St. Louis University
Explore the campus of St. Louis University as part of your travels around St. Louis. Wander around the area's picturesque gardens or experience its fascinating museums.

Scott Joplin House State Historic Site
Learn about the local history of St. Louis when you spend time at Scott Joplin House State Historic Site. Experience the area's great live music or attend a baseball game.

St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.

Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed theater scene or attend a baseball game.

Gateway Arch
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Midtown Hotel Deals

Element St. Louis Midtown
Good valet parking
Reviewed on Apr 1, 2026

Residence Inn by Marriott St Louis Downtown
Great, convenient location. Rooms were nice and complimentary breakfast was great.
Reviewed on Mar 31, 2026

Pear Tree Inn St. Louis Near Union Station
Room was decent. Nothing spectacular but functional. A little small, but the mattress was great and the shower pressure was amazing. The staff and the amenities made the stay a 5 star! Friendly and helpful staff. Wine and snacks each night. The kids loved the breakfast and free fountain drinks. Very ...
Reviewed on Apr 1, 2026

Drury Plaza Hotel St. Louis at the Arch
The staff at the Drury Inn bu the Arch are second to none! They were friendly, helpful, and efficient. The included meals and pool made traveling with our kids a relaxed and enjoyable time
Reviewed on Apr 1, 2026

Clayton Plaza Hotel & Extended Stay

21C Museum Hotel St Louis
Fun hotel.
Reviewed on Apr 1, 2026
Other neighborhoods around Midtown

The Gate
While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Enterprise Center.

Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and Enterprise Center are top sights worth seeing.

Lafayette Square
The restaurants and shopping are a few reasons travelers visit Lafayette Square. Though there aren't many top sights in the neighborhood, you can visit St. Louis Union Station and Enterprise Center, a few notable attractions nearby.

The Grove
The Grove might not have many top sights, but St. Louis Zoo and St. Louis Science Center are two attractions nearby that you can check out.

Shaw
While there might not be top attractions in Shaw, you can explore the larger area and discover places like Missouri Botanical Gardens and Arboretum and St. Louis Science Center.

Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
