A modern glass building with a curved facade and a sign reading "The Kentucky Center".

Southern Indiana 4 Stars Hotels

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Check availability on Southern Indiana 4 Star Hotels

Tonight
Oct 16 - Oct 17
Tomorrow
Oct 17 - Oct 18
This weekend
Oct 16 - Oct 18
Next weekend
Oct 23 - Oct 25

Our top choices for Southern Indiana 4-star hotels

A modern interior with large windows offering a city view, a circular light fixture, and leather seating.
A modern bar with a long counter, multiple shelves of liquor bottles, and cushioned bar stools.
A spacious room with a large dining table, comfortable seating, a sofa, and a view of a bridge.
A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.

1. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville
United States
Mark
₩188,022
₩221,226 total
includes taxes & fees
Nov 8 - Nov 9
Galt House Hotel Trademark Collection by Wyndham
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
A modern interior with a fireplace, bookshelves, and seating areas.
A lobby with a marble floor, a reception desk, and a large chandelier.
A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.

2. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville
United States
Samantha
₩168,376
₩198,111 total
includes taxes & fees
Oct 18 - Oct 19
Omni Louisville Hotel
A grand lobby with ornate columns, plush seating, and a chandelier.
A grand lobby with ornate ceiling and chandeliers, a large vase, and a seating area with multiple sofas and armchairs.
A grand lobby with ornate ceiling, multiple seating areas, and a staircase.
A grand dining area with ornate ceiling, chandeliers, and a bar area with a sign reading "Cigar Bar".

3. The Brown Hotel

The Brown Hotel
Downtown Louisville
United States
John
₩168,033
₩197,706 total
includes taxes & fees
Nov 15 - Nov 16
The Brown Hotel
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.
A modern hotel room with a living area, a dining area, and a bedroom.
A hotel dining area with long tables, booths, and a bar.
An indoor swimming pool with clear water, surrounded by white marble walls and columns, and furnished with lounge chairs and tables.

4. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
Downtown Louisville
United States
Frances
₩174,840
₩205,716 total
includes taxes & fees
Nov 15 - Nov 16
Embassy Suites Louisville Downtown
A modern lobby with a curved metallic structure, a seating area with a sofa and a small table, and an escalator in the background.
A modern indoor swimming pool with clear glass walls, lounge chairs, and a wooden wall in the background.
A reception area with a wooden wall and a neon sign that reads "Sway LOCAL SOUTHERN EATERY".
A bar area with wooden paneling, multiple seating arrangements, and a variety of liquor bottles displayed on shelves.

5. Hyatt Regency Louisville

Hyatt Regency Louisville
Downtown Louisville
United States
Lester
₩221,265
₩260,339 total
includes taxes & fees
Oct 30 - Oct 31
Hyatt Regency Louisville
A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.
A spacious lobby with a bar area, seating arrangements, and a visible kitchen bar.
A modern bar area with glass partitions, bar stools, and a variety of bottles.
A modern hotel room with a large window offering a city view, a cozy seating area with a sofa and chairs, a dining table with lamps, and a wooden floor.

6. Louisville Marriott Downtown

Louisville Marriott Downtown
Downtown Louisville
United States
Jason
₩184,480
₩217,058 total
includes taxes & fees
Nov 13 - Nov 14
Louisville Marriott Downtown
A classical gold statue in front of a multi-story building with large windows and a brick facade.
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.
A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.
A steam fountain in a brick alleyway.

7. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville
United States
Matt
₩204,020
₩246,755 total
includes taxes & fees
Nov 8 - Nov 9
21c Museum Hotel Louisville
A room with a checkered floor, leather armchairs, a sofa, and a small table with a glass. There are windows with arched tops and a view of buildings outside.
A yellow coffee shop counter with a menu board above, displaying various coffee and food items.
A bar area with a wooden bar counter, two stools, a chandelier, and a mirror.
A bedroom with a bed, a chair, a TV, and a window with curtains.

8. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
Downtown Louisville
United States
Tyler
₩181,035
₩213,006 total
includes taxes & fees
Oct 25 - Oct 26
Hotel Genevieve part of JdV by Hyatt
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.
An outdoor dining area with tables and chairs, a green building facade, and a row of plants along the wall.
A modern living room with a leather sectional sofa, a glass coffee table, and a view of the city skyline through large windows.
A bar with shelves of liquor bottles and a bartender preparing drinks.

9. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
Downtown Louisville
United States
Heather
₩305,641
₩359,617 total
includes taxes & fees
Nov 8 - Nov 9
Hotel Distil, Autograph Collection
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.
A modern restaurant interior with a staircase, round tables, and a brick wall.
A multi-level interior with a staircase, bookshelves, and a prominent sign reading "THE GRADY".
A modern hotel room with a large bed, a desk with a flat-screen TV, a green armchair, and a view of the city through large windows.

10. The Grady

The Grady
Downtown Louisville
United States
Donna
₩200,144
₩235,493 total
includes taxes & fees
Oct 18 - Oct 19
The Grady
An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.
A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.
A modern lobby with a central reception desk, seating area, and a large abstract wall art piece.
A modern living room with a sofa, a coffee table, a side table with a plant, and a view of a building with a clock tower.

11. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Downtown Louisville
United States
Cameron
₩240,817
₩283,345 total
includes taxes & fees
Oct 25 - Oct 26
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
A modern hotel entrance with a covered walkway, a parking area, and a building with multiple floors.
A fountain with multiple jets of water in front of a building with a curved facade and large windows.
A neatly made breakfast tray on a bed with a coffee pot, croissant, and fruit bowl.
A conference room with round tables, chairs, and a carpeted floor.

12. DoubleTree by Hilton Evansville

DoubleTree by Hilton Evansville
Downtown Evansville
United States
CheyAnne
₩135,642
₩155,988 total
includes taxes & fees
Nov 1 - Nov 2
DoubleTree by Hilton Evansville
A historic hotel with ornate architecture, a grand entrance, and a red carpet leading to the doors.
A grand staircase with ornate railings and a marble floor, leading to a high-ceilinged lobby with decorative moldings and a chandelier.
A grand lobby with marble floors, a staircase, and a reception desk.
A spacious living room with a fireplace, wooden paneling, a television, and a blue sofa.

13. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
Downtown Louisville
United States
Colleen
₩221,108
₩260,155 total
includes taxes & fees
Oct 29 - Oct 30
Seelbach Hilton Louisville Downtown
A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.
A modern KFC building with large glass windows, a prominent sign, and a well-lit entrance area.
A modern interior with a green wall, black chairs, and a ceiling with exposed beams and lights.
A modern, well-lit room with a large bed, a green sofa, a small round table, and a kitchen area in the background.

14. Stellar Suites

Stellar Suites
Downtown Louisville
United States
Kevin
₩155,079
₩250,043 total
includes taxes & fees
Oct 26 - Oct 27
Stellar Suites
A grand entrance with a staircase leading to a door, flanked by two lamp posts and a bench.
A grand hallway with a wooden floor, a staircase, a chandelier, and a large mirror.
A marble countertop with a tray of colorful glassware, a bottle, and two glasses. A framed painting hangs above, and two lamps are on either side.
A long table set with white tablecloths, gold chargers, and clear glassware.

15. The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
New Albany
United States
David
₩169,473
₩191,504 total
includes taxes & fees
Nov 8 - Nov 9
The Pepin Mansion Historic B&B
A modern lounge with leather sofas, a coffee table, and a view of a classical building.
A modern living room with a leather sofa, two coffee tables, and a chessboard. There are shelves with bottles and glasses, and a large window on the right.
A narrow corridor with exposed brick walls, wooden flooring, and a seating area with tables and chairs.
A building with a sign reading "Pursuit Spirits Co." and a large window display.

16. The Reserve on Main

The Reserve on Main
Downtown Louisville
United States
De'Carlon
The Reserve on Main
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a high-rise building with balconies.
A gym with exercise equipment, mirrors, and a TV screen.
A multi-story residential building with balconies, a brick facade, and large windows.
A modern living room with a dining area, a blue sofa, a ceiling fan, and a view of a balcony.

17. CozySuites at Nulu

CozySuites at Nulu
Downtown Louisville
United States
Jennifer
₩126,054
₩301,962 total
includes taxes & fees
Oct 26 - Oct 27
CozySuites at Nulu
A modern hotel with a 'Stay Apt Suites' sign, featuring a brick facade, large windows, and a parking lot.
In-room dining
Terrace/patio
Private kitchen

18. stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
Clarksville
Canada
Darlene
₩199,809
₩225,784 total
includes taxes & fees
Oct 27 - Oct 28
stayAPT Suites Louisville North-Clarksville
A large, multi-story building with a prominent tower and multiple windows.
A cozy seating area with two leather armchairs and a small round table. A table lamp and a wine glass are on the table.
A dining table set with placemats, folded napkins, cutlery, and a coffee cup.
A spacious living area with a large, ornate rug, a wooden bench, and a staircase with white balusters.

19. Bourbon Barrel Inn Bed & Breakfast

Bourbon Barrel Inn Bed & Breakfast
Old Louisville
United States
jonathan
Bourbon Barrel Inn Bed & Breakfast
A modern kitchen with wooden cabinets, a black microwave, and a stainless steel refrigerator.
A kitchen with a black refrigerator, a dining area with a table and chairs, and a living room with a blue sofa.
A kitchen with wooden cabinets, a refrigerator, a coffee maker, and a tiled backsplash.
A living room with a sofa, a coffee table, and a ceiling fan. There is a dining area with a table and chairs.

20. Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
Sellersburg
United States
Tammy
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
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Frequently asked questions

What are the best 4-star hotels in Southern Indiana?
Based on reviews by our guests, Galt House Hotel Trademark Collection by Wyndham is among the best 4-star hotels in Southern Indiana. Situated in Louisville, it includes massage services and beauty services. Hyatt Regency Louisville is another sought-after option here. Also with a 4-star rating and offering premium bedding and designer toiletries, you're sure to have a comfortable stay.
How much does it cost to stay in a 4-star hotel in Southern Indiana?
To book a 4-star hotel in Southern Indiana that's within your budget, take advantage of Expedia's handy filters. Take a look at what's available during your preferred dates and use our pricing filter to set your limit. You can also sort your results by the most budget-friendly option first.
  • Search for the lowest price from ₩155,988
What's the difference between 5-star and 4-star hotels in Southern Indiana?
Give yourself the luxury treatment during your Southern Indiana escape by checking in to a 4-star hotel. As well as featuring upmarket surroundings, these properties are typically packed with amenities such as large beds, bathrobes and plenty more. A 5-star hotel will go the extra mile to make your stay an even more indulgent and memorable one. 24-hour concierge assistance, luxurious spas and world-class dining are a few of the exclusive services and conveniences you'll likely be able to enjoy.

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