A bench, a bicycle, and a lake surrounded by trees.

Upstate South Carolina 4 Stars Hotels

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Check availability on Upstate South Carolina 4 Star Hotels

Tonight
Aug 22 - Aug 23
Tomorrow
Aug 23 - Aug 24
Next weekend
Aug 28 - Aug 30
In two weeks
Sep 4 - Sep 6

Our top choices for Upstate South Carolina 4-star hotels

1. Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection
Greenville Downtown
United States
David
₩488,075
₩552,988 total
includes taxes & fees
Sep 13 - Sep 14
Grand Bohemian Lodge Greenville, Autograph Collection

2. Hotel Hartness

Hotel Hartness
Greenville
United States
Cornelius
₩230,302
₩306,950 total
includes taxes & fees
Aug 30 - Aug 31
Hotel Hartness

3. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
Clemson
United States
Laurrie
₩331,213
₩367,646 total
includes taxes & fees
Aug 31 - Sep 1
The Shepherd Hotel Downtown Clemson

4. The Westin Poinsett Greenville

The Westin Poinsett Greenville
Greenville Downtown
United States
Andre
₩275,780
₩316,617 total
includes taxes & fees
Sep 6 - Sep 7
The Westin Poinsett Greenville

5. Greenville Marriott

Greenville Marriott
Greenville
United States
John
₩145,512
₩164,864 total
includes taxes & fees
Sep 5 - Sep 6
Greenville Marriott

6. Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa
Greenville Downtown
United States
NEOLA
₩119,230
₩135,087 total
includes taxes & fees
Aug 30 - Aug 31
Mint House Greenville Downtown by Kasa

7. The Abernathy of Clemson

The Abernathy of Clemson
Clemson
United States
Robert
₩210,784
₩233,969 total
includes taxes & fees
Sep 7 - Sep 8
The Abernathy of Clemson

8. The Station by Compo Hotels

The Station by Compo Hotels
Travelers Rest
United States
Anonymous traveler
₩357,142
₩507,186 total
includes taxes & fees
Sep 21 - Sep 22
The Station by Compo Hotels

9. Hotel Domestique

Hotel Domestique
Travelers Rest
United States
Chuck
₩514,571
₩566,028 total
includes taxes & fees
Aug 24 - Aug 25
Hotel Domestique

10. Landing Apartments Greer - Sugar Creek

Landing Apartments Greer - Sugar Creek
Greer
United States
Amanda
Landing Apartments Greer - Sugar Creek

12. Designer Retreat w/ Pool, Golf + Beach Access!

Designer Retreat w/ Pool, Golf + Beach Access!
Salem
United States
Anonymous traveler
Designer Retreat w/ Pool, Golf + Beach Access!

14. Landing Furnished Apartments - Spartanburg, SC

Landing Furnished Apartments - Spartanburg, SC
Spartanburg
Landing Furnished Apartments - Spartanburg, SC

18. Lake Keowee Condo: Resort Pools & Lake Access!

Lake Keowee Condo: Resort Pools & Lake Access!
Salem
Lake Keowee Condo: Resort Pools & Lake Access!

20. Keowee Keys Home w/ Mountains View & Lake Access!

Keowee Keys Home w/ Mountains View & Lake Access!
Salem
United States
KURT
Keowee Keys Home w/ Mountains View & Lake Access!
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Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

See all hotels in Upstate South Carolina
An aerial view of a park with a winding path, trees in autumn colors, and a bridge.
Photo by Visit Greenville, South Carolina

Top Upstate South Carolina Hotel Reviews

Hotel Hartness

Hotel Hartness

10/10 Excellent
"Amazing!"
Kim 1-night trip
Posted 5 days ago
Hotel Hartness
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

10/10 Excellent
"It was amazing! Check in took a while though. Everyone was waiting around in the lobby for their rooms. We got ours just before 4 pm -which was tight for our 5:30 pm event."
Gail 1-night trip
Posted 8 days ago
Grand Bohemian Lodge Greenville, Autograph Collection

Frequently asked questions

What are the best 4-star hotels in Upstate South Carolina?
Stay at Greenville Marriott and get ready for upscale comfort and plenty of handy amenities. This 4-star hotel in Greer, Upstate South Carolina, is highly recommended by Expedia guests.
How much does it cost to stay in a 4-star hotel in Upstate South Carolina?
Expedia can help you quickly locate the perfect 4-star hotel for your getaway in Upstate South Carolina. Use our handy filter tool to tailor your search by things like amenities, budget and property star rating and get access to fabulous deals in a few clicks.
  • Search for the lowest price from ₩135,087
What's the difference between 5-star and 4-star hotels in Upstate South Carolina?
Offering a friendly guest experience and upmarket décor, 4-star hotels are a wonderful option for your Upstate South Carolina trip. These kinds of accommodations generally come with loads of handy amenities that make it simple to kick back and relax — think large beds, bathrobes, restaurants and pools. Or live the high life at a 5-star hotel designed to pamper with exclusive perks and amenities. Full-service health clubs, premium toiletries and fine dining are typically featured at these deluxe retreats.

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