A beach with palm trees, people relaxing on chairs, and colorful kayaks.

Florida Keys 5 Stars Hotels

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Check availability on Florida Keys 5 Star Hotels

This weekend
Jul 3 - Jul 5
Next weekend
Jul 10 - Jul 12

Our top choices for Florida Keys 5-star hotels

Balcony

Cheeca Lodge & Spa

Cheeca Lodge & Spa
5.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1,324 reviews)
"Perfect couple stay"
United States
Yiset
The price is ₩367,451
₩525,816 total
includes taxes & fees
Jul 15 - Jul 16
Cheeca Lodge & Spa
On the beach, sun loungers, beach umbrellas, beach towels

Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa
5.0 star property
Marathon
9.2 out of 10, Wonderful, (1,174 reviews)
"Beautiful hotel, grounds and wonderful staff."
United States
Anna
The price is ₩372,447
₩512,864 total
includes taxes & fees
Jul 14 - Jul 15
Isla Bella Beach Resort & Spa
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Florida Keys.
Reefhouse Resort & Marina

Reefhouse Resort & Marina

103800 Overseas Hwy Key Largo FL
The price is ₩321,327 per night from Jul 27 to Jul 28
₩321,327
₩422,999 total
Jul 27 - Jul 28
includes taxes & fees
9.4/10 Exceptional! (1,469 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Florida Keys

Snorkel crystal-clear waters teeming with colorful fish, then feast on fresh-caught lobster at a laid-back waterfront shack. Drive the scenic Overseas Highway, stopping at Key West's Ernest Hemingway Home and Dry Tortugas National Park for island adventures.

See all hotels in Florida Keys
A beach with palm trees, people relaxing on chairs, and colorful kayaks.

Top Florida Keys Hotel Reviews

Cheeca Lodge & Spa

Cheeca Lodge & Spa

10/10 Excellent
"Very nicely put together and well maintained. Staff are great and the views are stunning. We will go back again."
Tony 2-night trip
Posted 2 days ago
Cheeca Lodge & Spa
Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

10/10 Excellent
"Stayed in oceanfront balcony on third floor. Room was very spacious. Balcony was big with two chairs, a table and a couch. Beautiful view from the balcony."
Aaron 1-night trip
Posted 3 days ago
Isla Bella Beach Resort & Spa

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Florida Keys?
You can find several pricing options for a 5-star hotel in Florida Keys on Expedia. The amount you pay will depend on your travel dates, length of your trip and other factors. Compare all of the available accommodations for your chosen dates and make use of our pricing and other filters to score the ideal upscale stay.

  • Search for the lowest price per night from ₩406,078

What makes a hotel 5 stars in Florida Keys?
From gourmet restaurants and 24-hour gyms to pools and deluxe bedding, the 5-star experience in Florida Keys is all about comfort and indulgence. But it calls for more than just top-notch perks to earn a 5-star rating. Stays must also provide outstanding guest-focused services like in-room massage treatments, on-site laundry and dry cleaning and 24/7 room service.
Are there any 5-star all-inclusive resorts in Florida Keys?
Find an indulgent escape that includes your lodging, meals, drinks and entertainment in Florida Keys with Expedia's filters. Search for hotels rated 5 stars and click on the "All inclusive" filter. Double-check what's included in the upfront price. This way, you'll be ready to maximize all the premium perks from the moment you arrive.