Find All Upstate South Carolina Hotels
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Find All Upstate South Carolina Hotels
We have found 3148 Upstate South Carolina Hotels
- Embassy Suites Greenville Golf Resort & Conference Center
- Hilton Greenville
- Hyatt Place Greenville/Haywood
- Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
- Grand Bohemian Lodge Greenville, Autograph Collection
- Best Western Plus Greenville I-385 Inn & Suites
- Hotel Hartness
- Best Western Plus Clemson Hotel & Conference Center
- Hyatt Place Greenville Downtown
- Lakeside Lodge Clemson
- Days Inn by Wyndham Anderson
- Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd
- La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
- Comfort Inn Greenville - Haywood Mall
- Embassy Suites by Hilton Greenville Downtown Riverplace
- Aloft by Marriott Greenville Downtown
- Hyatt Regency Greenville
- The Westin Poinsett Greenville
- La Quinta by Wyndham Haywood Mall-Near Greenville Downtown
- Hampton Inn & Suites Greenville-Downtown-RiverPlace
- Comfort Inn & Suites Clemson - University Area
- Courtyard by Marriott Greenville Haywood Mall
- Best Western Spartanburg I-26
- Drury Inn & Suites Greenville
- Comfort Suites At WestGate Mall
- Clemson University's James F. Martin Inn
- Homewood Suites by Hilton Greenville Downtown
- Inn @ Clemson
- Spartanburg Marriott
- SpringHill Suites by Marriott Greenville Downtown
- Days Inn by Wyndham Greenville
- The Abernathy of Clemson
- Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
- Comfort Suites Greenville Airport
- Holiday Inn Express & Suites Greenville - Downtown by IHG
- Greenville Inn and Suites
- Quality Inn & Suites Greenville - Haywood Mall
- Urban Boutique Hotel, BW Signature Collection
- Quality Inn Seneca US-123
- AC Hotel By Marriott Greenville
- Clarion Inn
- Woodspring Suites Anderson North I-85
- Wingate by Wyndham - Greenville-Airport
- Horizon Inn & Suites
- The Shepherd Hotel Downtown Clemson
- Baymont by Wyndham Greenville Woodruff Rd
- Holiday Inn Greenville - Woodruff Road by IHG
- Extended Stay America Premier Suites Greenville Woodruff Rd
- Woodspring Suites Greenville Airport
- Courtyard by Marriott Greenville Downtown
- Fairfield Inn & Suites by Marriott Greenville Simpsonville
- Home2 Suites by Hilton Greenville Downtown
- Courtyard Marriott Clemson
- Greenville Marriott
- The Inn at Patrick Square
- Hilton Garden Inn Greenville
- Quality Inn & Suites Easley - Greenville
- Rodeway Inn Expo Center
- Motel 6 Spartanburg, Sc – Northwest / Business 85
- Quality Inn Clemson near University
- Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
- Holiday Inn Express & Suites Greenville Airport by IHG
- Fairfield Inn by Marriott Greenville-Spartanburg Airport
- Best Western Spartanburg Northwest
- Four Points by Sheraton Spartanburg
- Hampton Inn & Suites Greenville Airport, SC
- Tru by Hilton Greenville Woodruff Road
- AC Hotel by Marriott Spartanburg
- Quality Inn Simpsonville - Greenville
- Sleep Inn at Greenville Convention Cente
- Studio 6 Greenville, SC
- Courtyard Greenville-Spartanburg by Marriott
- Comfort Inn & Suites Greer - Greenville
- Baymont by Wyndham Greenwood
- Tru by Hilton Seneca Clemson
- Studio 6 Suites Greenville, SC - Haywood Mall
- Comfort Suites Piedmont - Greenville South
- Tru by Hilton Spartanburg
- Holiday Inn Anderson by IHG
- Holiday Inn Express & Suites Greenville - Taylors by IHG
- Courtyard by Marriott Greenville Mauldin
- Baymont by Wyndham Easley/Greenville
- WoodSpring Suites Greenville Haywood Mall
- Fairfield Inn & Suites Seneca Clemson Univ Area
- Microtel Inn & Suites by Wyndham Anderson/Clemson
- DoubleTree by Hilton Greenville Woodruff Road
- Hampton Inn Greenville I-385 - Woodruff Rd.
- WoodSpring Suites Greenville Central I-85
- Comfort Suites Anderson-Clemson
- Days Inn by Wyndham Easley/Greenville/Clemson Area
- Hampton Inn Greer Greenville, SC
- MainStay Suites Greenville Airport
- Hampton Inn Gaffney
- Holiday Inn Express Gaffney by IHG
- Comfort Suites Simpsonville - Greenville
- Hilton Garden Inn Spartanburg
Let Expedia take you to the best Hotels in Upstate South Carolina. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.