Find hotels in Downtown, Seneca

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Downtown hotels

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very Good, (697 reviews)
"Very pleasant and helpful staff. Comfortable room though fairly small."
United States
William
The price is ₩127,432
₩149,516 total
includes taxes & fees
Jun 1 - Jun 2
Quality Inn Seneca Clemson Area US-123

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
2 km from Downtown
9.4 out of 10, Exceptional, (227 reviews)
"Excellent in every way … staff, room, amenities and very comfortable bed!"
United States
Sarah
The price is ₩190,200
₩209,220 total
includes taxes & fees
May 28 - May 29
Fairfield Inn & Suites Seneca Clemson Univ Area

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
15.2 km from Downtown
9.8 out of 10, Exceptional, (842 reviews)
"Very nice hotel - very clean, beautiful decor."
United States
Elizabeth
The price is ₩233,943
₩259,676 total
includes taxes & fees
Jun 2 - Jun 3
The Inn at Patrick Square

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
2.5 star property
25 km from Downtown
9.2 out of 10, Wonderful, (614 reviews)
"Clean rooms, friendly staff, great breakfast options!"
United States
Lauren
The price is ₩161,847
₩179,651 total
includes taxes & fees
May 10 - May 11
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
8.6 km from Downtown
9.0 out of 10, Wonderful, (1,002 reviews)
"This place is tops! The area is great, rooms were wonderful, and amenities were amazing. Definitely plan on staying again asap!"
United States
Valarie Tina
The price is ₩161,195
₩200,104 total
includes taxes & fees
May 9 - May 10
Lakeside Lodge Clemson

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
7.5 km from Downtown
9.8 out of 10, Exceptional, (71 reviews)
"Great getaway!!!"
United States
Latoya
The price is ₩146,406
₩226,116 total
includes taxes & fees
May 12 - May 13
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
11.8 km from Downtown
8.2 out of 10, Very Good, (1,008 reviews)
"Great location to area amenities and nice attached restaurant and breakfast buffet."
United States
Erin Kay
The price is ₩162,156
₩179,994 total
includes taxes & fees
May 17 - May 18
Best Western Plus Clemson Hotel & Conference Center

Rodeway Inn & Suites Walhalla

Rodeway Inn & Suites Walhalla
2.0 star property
12.8 km from Downtown
7.6 out of 10, Good, (183 reviews)
"It was adequate, priced right. "
United States
Aaron
The price is ₩119,402
₩133,134 total
includes taxes & fees
Jun 4 - Jun 5
Rodeway Inn & Suites Walhalla

Hampton Inn & Suites Lavonia

Hampton Inn & Suites Lavonia
2.5 star property
30.7 km from Downtown
9.0 out of 10, Wonderful, (403 reviews)
"The hotel was very clean. I stayed on the 2nd floor, and the carpets seemed brand new. Staff was super helpful."
United States
Tina
The price is ₩183,525
₩218,448 total
includes taxes & fees
May 21 - May 22
Hampton Inn & Suites Lavonia

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
11.7 km from Downtown
8.2 out of 10, Very Good, (1,007 reviews)
"Great breakfast and friendly staff made our stay enjoyable."
United States
Lon
The price is ₩149,586
₩166,041 total
includes taxes & fees
May 31 - Jun 1
Comfort Inn & Suites Clemson - University Area

Residence Inn by Marriott Anderson Clemson

Residence Inn by Marriott Anderson Clemson
3.0 star property
25.1 km from Downtown
9.6 out of 10, Exceptional, (104 reviews)
"Staff was friendly and helpful. The property and rooms were very clean."
United States
Anuphinh
The price is ₩210,402
₩233,546 total
includes taxes & fees
May 24 - May 25
Residence Inn by Marriott Anderson Clemson

Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast
4.0 star property
16.3 km from Downtown
10.0 out of 10, Exceptional, (88 reviews)
"The was by far one of the best bed and breakfast places that I have ever stayed in. The house is beautiful, the rooms and spotless and the breakfast is amazing. "
United States
Jennifer Ann
The price is ₩186,315
₩280,751 total
includes taxes & fees
May 10 - May 11
Liberty Hall Bed and Breakfast

Hilton Garden Inn Anderson

Hilton Garden Inn Anderson
3.0 star property
25.7 km from Downtown
9.0 out of 10, Wonderful, (720 reviews)
"Great place to stay"
United States
Maureen
The price is ₩146,516
₩162,633 total
includes taxes & fees
May 18 - May 19
Hilton Garden Inn Anderson

Holiday Inn Express Hotel & Suites Lavonia by IHG

Holiday Inn Express Hotel & Suites Lavonia by IHG
2.5 star property
30.7 km from Downtown
8.8 out of 10, Excellent, (418 reviews)
"Great place ro stay"
United States
Ida
The price is ₩200,102
₩237,474 total
includes taxes & fees
May 27 - May 28
Holiday Inn Express Hotel & Suites Lavonia by IHG

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
8.4 km from Downtown
9.2 out of 10, Wonderful, (837 reviews)
"Great location and facilities"
United States
Brian
The price is ₩170,955
₩188,051 total
includes taxes & fees
May 19 - May 20
Tru by Hilton Seneca Clemson

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
10.3 km from Downtown
9.4 out of 10, Exceptional, (1,003 reviews)
"Lovely place to stay right on the lake. "
United States
Sara
The price is ₩146,406
₩162,511 total
includes taxes & fees
May 11 - May 12
Clemson University's James F. Martin Inn

Holiday Inn Anderson by IHG

Holiday Inn Anderson by IHG
3.0 star property
29.5 km from Downtown
8.8 out of 10, Excellent, (724 reviews)
"Great location and very clean."
United States
Amy
The price is ₩162,674
₩180,568 total
includes taxes & fees
May 24 - May 25
Holiday Inn Anderson by IHG

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
10.6 km from Downtown
9.8 out of 10, Exceptional, (796 reviews)
"Great location great restaurant"
United States
Jennifer
The price is ₩244,713
₩271,639 total
includes taxes & fees
May 10 - May 11
The Shepherd Hotel Downtown Clemson

Hampton Inn Anderson

Hampton Inn Anderson
2.5 star property
25 km from Downtown
8.8 out of 10, Excellent, (416 reviews)
"Convenient location and friendly front desk staff"
United States
Mark
The price is ₩167,027
₩185,400 total
includes taxes & fees
May 25 - May 26
Hampton Inn Anderson

The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
10.1 km from Downtown
9.6 out of 10, Exceptional, (594 reviews)
"Easy parking, great location. Will stay there again"
United States
William
The price is ₩224,933
₩249,675 total
includes taxes & fees
May 11 - May 12
The Abernathy of Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown

Find the best Downtown areas and neighborhoods for the activities you enjoy most.

Serenity Bay

Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.

Pine Ridge Point

While Pine Ridge Point isn't home to many top sights, Lake Keowee and Keowee Key Golf Course are some notable places to visit nearby.

Indian Oaks

While there might not be top attractions in Indian Oaks, you can explore the larger area and discover places like Oconee County Library Seneca Branch and Seneca Historic District.

Keowee Plantation

When in Keowee Plantation, you can plan a visit to Oconee County Library Seneca Branch and Seneca Historic District, some noteworthy sights in the nearby area.

Top Downtown Hotel Reviews

Frequently asked questions

What is Downtown like?
Travelers to the Downtown neighborhood in Seneca will be sure to enjoy their stay. Be sure to check out Seneca Historic District and Oconee County Library Seneca Branch as part of your Downtown travel plans.
Where is the best place to stay in Downtown?
Based on our traveler data, Quality Inn Seneca Clemson Area US-123 is one of the top choices for your stay in Downtown. This hotel offers free breakfast and free parking.
How many hotels can I expect to find in Downtown?
If you're searching for places to stay in Seneca, choose from one of Expedia's 13 hotels and other accommodations in Downtown.
If I need to cancel my hotel reservation in Downtown, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to view the best deals in Downtown.
Where can I learn more about changing or cancelling my trip to Downtown?
To find more details about rescheduling or cancelling your trip to Downtown, head over to our customer service page.
What can I see and do in this Seneca neighborhood?
Seneca Historic District, Oconee County Library Seneca Branch, and Blue Ridge Arts Center are just a few attractions to check out in Downtown. As you're discovering the neighborhood, Bertha Lee Strickland Cultural Museum and The Gauntlet are some other places worth a visit. Seneca City Hall, Golden Corner Plaza, and Oconee Community Theatre are just a few of the places to visit in and around Downtown. While you're out sightseeing in Seneca, be sure to visit other sights like Applewood Shopping Center or Wyndham Plaza.