What is Downtown like?

Travelers to the Downtown neighborhood in Seneca will be sure to enjoy their stay. Be sure to check out Oconee County Library Seneca Branch and Blue Ridge Arts Center as part of your Downtown travel plans.

Where is the best place to stay in Downtown?

Based on our traveler data, Quality Inn Seneca Clemson Area US-123 is one of the top choices for your stay in Downtown. This hotel offers free breakfast and free parking.

How many hotels can I expect to find in Downtown?

If you're searching for places to stay in Seneca, choose from one of Expedia's 13 hotels and other accommodations in Downtown.

If I need to cancel my hotel reservation in Downtown, will I receive a refund?

Yes! You'll find that most room reservations are fully refundable provided that you cancel before the hotel’s cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to view the best deals in Downtown.

Where can I learn more about changing or cancelling my trip to Downtown?

To find more details about rescheduling or cancelling your trip to Downtown, head over to our customer service page .

What can I see and do in this Seneca neighborhood?

Oconee County Library Seneca Branch, Blue Ridge Arts Center, and Seneca Historic District are just a few attractions to check out in Downtown. As you're discovering the neighborhood, Bertha Lee Strickland Cultural Museum and The Gauntlet are some other places worth a visit. Seneca City Hall, Golden Corner Plaza, and Oconee Community Theatre are just a few of the places to visit in and around Downtown. While you're out sightseeing in Seneca, be sure to visit other sights like Applewood Shopping Center or Wyndham Plaza.

Top Downtown Hotels

A large lake surrounded by dense forests.

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Our top choices for Downtown hotels

1. Quality Inn Seneca Clemson Area US-123

Downtown

Anthony

₩141,595 total

includes taxes & fees

Jul 26 - Jul 27

2. Fairfield Inn & Suites Seneca Clemson Univ Area

2 km from Downtown

BRIAN

₩202,691 total

includes taxes & fees

Jul 27 - Jul 28

Standard Room, 1 King Bed, Non Smoking, Jetted Tub | Desk, laptop workspace, blackout drapes, iron/ironing board

3. Best Western Seneca-Clemson

1.7 km from Downtown

Michelle

₩165,887 total

includes taxes & fees

Jul 24 - Jul 25

4. Hampton Inn & Suites Seneca-Clemson Area

2.2 km from Downtown

Daren

₩192,978 total

includes taxes & fees

Jul 26 - Jul 27

5. Days Inn by Wyndham Seneca / Clemson Area

3.1 km from Downtown

Karl

₩116,122 total

includes taxes & fees

Jul 29 - Jul 30

6. Lakeside Lodge Clemson

8.6 km from Downtown

JEFFREY

₩200,056 total

includes taxes & fees

Jul 24 - Jul 25

7. Clemson University's James F. Martin Inn

10.3 km from Downtown

Jesse

₩236,323 total

includes taxes & fees

Jul 23 - Jul 24

8. Best Western Plus Clemson Hotel & Conference Center

11.8 km from Downtown

Tammy

₩179,950 total

includes taxes & fees

Aug 4 - Aug 5

9. The Inn at Patrick Square

15.2 km from Downtown

april

₩244,494 total

includes taxes & fees

Jul 23 - Jul 24

10. Inn @ Clemson

11.6 km from Downtown

Scott

₩131,454 total

includes taxes & fees

Jul 23 - Jul 24

11. Tru by Hilton Seneca Clemson

8.4 km from Downtown

Jason

₩169,367 total

includes taxes & fees

Aug 2 - Aug 3

Outdoor pool, open 9:00 AM to 9:00 PM, sun loungers

12. Fairfield Inn & Suites by Marriott Anderson Clemson

25 km from Downtown

Malerion

₩160,973 total

includes taxes & fees

Jul 28 - Jul 29

Suite, 1 King Bed with Sofa bed, Non Smoking (Efficiency) | Premium bedding, desk, laptop workspace, blackout drapes

13. Comfort Inn & Suites Clemson - University Area

11.7 km from Downtown

Jessica

₩179,269 total

includes taxes & fees

Jul 25 - Jul 26

14. Courtyard Marriott Clemson

12.9 km from Downtown

Joanna

₩211,707 total

includes taxes & fees

Aug 2 - Aug 3

15. Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

25 km from Downtown

Edna

₩163,892 total

includes taxes & fees

Aug 9 - Aug 10

16. Hilton Garden Inn Anderson

25.7 km from Downtown

Gina

₩173,577 total

includes taxes & fees

Aug 9 - Aug 10

17. The Abernathy of Clemson

10.1 km from Downtown

Robert

₩264,385 total

includes taxes & fees

Jul 28 - Jul 29

18. The Shepherd Hotel Downtown Clemson

10.6 km from Downtown

Amy

₩277,355 total

includes taxes & fees

Jul 28 - Jul 29

19. Country Inn & Suites by Radisson, Anderson, SC

25.2 km from Downtown

Kimberly

₩172,976 total

includes taxes & fees

Aug 16 - Aug 17

20. Hampton Inn & Suites Lavonia

30.7 km from Downtown

Wendy

₩222,526 total

includes taxes & fees

Aug 2 - Aug 3

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Where to stay in Downtown

Find the best Downtown areas and neighborhoods for the activities you enjoy most.

Serenity Bay

Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.

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A sunset over a calm lake with a kayaker and a large tree on the shore.

Pine Ridge Point

While Pine Ridge Point isn't home to many top sights, South Beach and Lake Keowee are some notable places to visit nearby.

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Indian Oaks

While there might not be top attractions in Indian Oaks, you can explore the larger area and discover places like Oconee County Library Seneca Branch and Keowee Reservoir.

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Keowee Plantation

When in Keowee Plantation, you can plan a visit to Oconee County Library Seneca Branch and Keowee Reservoir, some noteworthy sights in the nearby area.

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Top Downtown Hotel Reviews

Lakeside Lodge Clemson

10/10 Excellent

"The only place we will stay!"

The Shepherd Hotel Downtown Clemson

10/10 Excellent

"We have found an absolute treasure in downtown Clemson, S.C.! From the moment we arrived we were greeted with smiling faces that made us feel like we were honored guests. From the maintenance staff to the front desk, everyone was eager to help us relax and enjoy our stay. The bar service was excellent, and we really enjoyed our hand mixed signature cocktails on the terrace overlooking downtown and Death Valley. The hotel is just steps from the campus and about a 15-minute walk to the world's best ice cream at Clemson's famous '55 Exchange. The hotel itself is absolutely beautiful, the bathrooms are spotless, and the bedding in our room was perfectly comfortable. There are plenty of boutiques, restaurants, and bars in walking distance. There are also a number of state parks, Lake Hartwell, and the South Carolina Botanical Garden if you love to get outside. The Clemson University campus, though experiencing exponential growth and construction projects, is still full of natural beauty worth exploring. Being it was summer and most students had left campus for break; the area bars and restaurants were much less crowded and relaxed. We look forward to staying here again soon."

Best Western Plus Clemson Hotel & Conference Center

10/10 Excellent

"Location was great for our visit to Clemson University. Close to everything. Good breakfast included in our room, Spacious rooms and confortable beds. The only suggestion would be that the hotel in general needs to be refreshed. Although well maintained, you can tell that it needs some updating."

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Our top choices for Downtown hotels

1. Quality Inn Seneca Clemson Area US-123

2. Fairfield Inn & Suites Seneca Clemson Univ Area

3. Best Western Seneca-Clemson

4. Hampton Inn & Suites Seneca-Clemson Area

5. Days Inn by Wyndham Seneca / Clemson Area

6. Lakeside Lodge Clemson

7. Clemson University's James F. Martin Inn

8. Best Western Plus Clemson Hotel & Conference Center

9. The Inn at Patrick Square

10. Inn @ Clemson

11. Tru by Hilton Seneca Clemson

12. Fairfield Inn & Suites by Marriott Anderson Clemson

13. Comfort Inn & Suites Clemson - University Area

14. Courtyard Marriott Clemson

15. Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

16. Hilton Garden Inn Anderson

17. The Abernathy of Clemson

18. The Shepherd Hotel Downtown Clemson

19. Country Inn & Suites by Radisson, Anderson, SC

20. Hampton Inn & Suites Lavonia

Where to stay in Downtown

Serenity Bay

Pine Ridge Point

Indian Oaks

Keowee Plantation

Top Downtown Hotel Reviews

Lakeside Lodge Clemson

The Shepherd Hotel Downtown Clemson

Best Western Plus Clemson Hotel & Conference Center

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

The Abernathy of Clemson

Quality Inn Clemson near University

Frequently asked questions

Find hotels in Downtown, Seneca

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Our top choices for Downtown hotels

1. Quality Inn Seneca Clemson Area US-123

2. Fairfield Inn & Suites Seneca Clemson Univ Area

3. Best Western Seneca-Clemson

4. Hampton Inn & Suites Seneca-Clemson Area

5. Days Inn by Wyndham Seneca / Clemson Area

6. Lakeside Lodge Clemson

7. Clemson University's James F. Martin Inn

8. Best Western Plus Clemson Hotel & Conference Center

9. The Inn at Patrick Square

10. Inn @ Clemson

11. Tru by Hilton Seneca Clemson

12. Fairfield Inn & Suites by Marriott Anderson Clemson

13. Comfort Inn & Suites Clemson - University Area

14. Courtyard Marriott Clemson

15. Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

16. Hilton Garden Inn Anderson

17. The Abernathy of Clemson

18. The Shepherd Hotel Downtown Clemson

19. Country Inn & Suites by Radisson, Anderson, SC

20. Hampton Inn & Suites Lavonia

Where to stay in Downtown

Serenity Bay

Pine Ridge Point

Indian Oaks

Keowee Plantation

Top Downtown Hotel Reviews

Lakeside Lodge Clemson

Frequently asked questions