Find hotels in Medical Center Area, Boston

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Medical Center Area hotels

The Inn at Longwood Medical

The Inn at Longwood Medical
3.5 star property
Medical Center Area
8.4 out of 10, Very Good, (1,001 reviews)
"A great experience from parking, service, cleanliness. Great access to hospitals and great on site restaurant"
United States
Gayle
The price is ₩410,871
₩521,471 total
includes taxes & fees
May 2 - May 3
The Inn at Longwood Medical

citizenM Boston Back Bay

citizenM Boston Back Bay
4.0 star property
1.6 km from Medical Center Area
9.4 out of 10, Exceptional, (2,628 reviews)
"We would stay again!"
United States
Laura
The price is ₩294,007
₩342,378 total
includes taxes & fees
May 10 - May 11
citizenM Boston Back Bay

The Midtown Hotel MOD Collection by Sonesta

The Midtown Hotel MOD Collection by Sonesta
2.0 star property
Prudential - St. Botolph, 1.8 km from Medical Center Area
8.4 out of 10, Very Good, (274 reviews)
"Hotel Location is convenient and near the train station"
Hong Kong SAR China
Edmond
The price is ₩308,781
₩359,589 total
includes taxes & fees
May 25 - May 26
The Midtown Hotel MOD Collection by Sonesta

Renaissance® Boston Seaport District

Renaissance® Boston Seaport District
4.0 star property
Seaport District, 5.4 km from Medical Center Area
9.0 out of 10, Wonderful, (1,002 reviews)
"Great spot to stay!"
United States
Kenneth
The price is ₩249,684
₩350,977 total
includes taxes & fees
May 10 - May 11
Renaissance® Boston Seaport District

Seaport Hotel Boston

Seaport Hotel Boston
4.0 star property
Seaport District, 5.3 km from Medical Center Area
9.6 out of 10, Exceptional, (4,248 reviews)
"Beautiful rooms Excellent friendly and helpful staff Great breakfast and dinners !"
United States
Susan
The price is ₩249,906
₩341,411 total
includes taxes & fees
May 7 - May 8
Seaport Hotel Boston

Battery Wharf Hotel, Boston Waterfront

Battery Wharf Hotel, Boston Waterfront
4.5 star property
North End, 5.4 km from Medical Center Area
8.8 out of 10, Excellent, (1,817 reviews)
"Wonderful hotel and staff! Great location, I would definitely stay here again!"
United States
Tammy
The price is ₩308,781
₩386,615 total
includes taxes & fees
May 3 - May 4
Battery Wharf Hotel, Boston Waterfront

YOTEL Boston

YOTEL Boston
4.0 star property
4.9 km from Medical Center Area
8.6 out of 10, Excellent, (2,494 reviews)
"Great hotel to stay in, lots of places to eat and close to the airport. "
United Kingdom
Stephen
The price is ₩264,458
₩385,378 total
includes taxes & fees
May 10 - May 11
YOTEL Boston

Hyatt Place Boston/Seaport District

Hyatt Place Boston/Seaport District
3.0 star property
Seaport District, 5.6 km from Medical Center Area
9.4 out of 10, Exceptional, (2,353 reviews)
"Great place to stay"
Germany
Ingo
The price is ₩294,007
₩342,378 total
includes taxes & fees
May 3 - May 4
Hyatt Place Boston/Seaport District

Hyatt Regency Boston

Hyatt Regency Boston
4.0 star property
Downtown Crossing, 3.9 km from Medical Center Area
9.0 out of 10, Wonderful, (2,001 reviews)
"Excellent hotel and great location!"
United States
Toni
The price is ₩288,097
₩387,217 total
includes taxes & fees
May 10 - May 11
Hyatt Regency Boston

Hampton Inn Boston Seaport District

Hampton Inn Boston Seaport District
3.0 star property
Seaport District, 5.4 km from Medical Center Area
9.2 out of 10, Wonderful, (2,849 reviews)
"Great stay!"
United States
Cecilia
The price is ₩256,894
₩299,154 total
includes taxes & fees
May 10 - May 11
Hampton Inn Boston Seaport District

Aloft by Marriott, Boston Seaport District

Aloft by Marriott, Boston Seaport District
3.0 star property
Seaport District, 4.9 km from Medical Center Area
8.8 out of 10, Excellent, (1,446 reviews)
"Clean well maintained useful location"
United States
Clyde
The price is ₩257,071
₩342,378 total
includes taxes & fees
May 10 - May 11
Aloft by Marriott, Boston Seaport District

Omni Boston Hotel at the Seaport

Omni Boston Hotel at the Seaport
5.0 star property
Seaport District, 5.1 km from Medical Center Area
9.2 out of 10, Wonderful, (4,609 reviews)
"Great staff great stay"
Canada
Elson
The price is ₩353,118
₩471,430 total
includes taxes & fees
May 10 - May 11
Omni Boston Hotel at the Seaport

Copley House

Copley House
3.0 star property
Prudential - St. Botolph, 2 km from Medical Center Area
9.2 out of 10, Wonderful, (2,074 reviews)
"Super convenient location and helpful staff throughout the entire stay!"
United States
Anessa
The price is ₩299,178
₩343,905 total
includes taxes & fees
May 2 - May 3
Copley House

Sonesta Select Boston Danvers

Sonesta Select Boston Danvers
3.0 star property
27.6 km from Medical Center Area
8.6 out of 10, Excellent, (1,001 reviews)
"Parking safe, room very clean, staff very friendly"
United States
Leonar
The price is ₩190,144
₩212,390 total
includes taxes & fees
May 7 - May 8
Sonesta Select Boston Danvers

Nantasket Beach Resort

Nantasket Beach Resort
3.0 star property
21.1 km from Medical Center Area
8.6 out of 10, Excellent, (1,000 reviews)
"Everything was perfect best stay ever "
United States
Hayley
The price is ₩192,976
₩251,854 total
includes taxes & fees
May 4 - May 5
Nantasket Beach Resort

The Revolution Hotel

The Revolution Hotel
3.5 star property
2.8 km from Medical Center Area
9.0 out of 10, Wonderful, (2,579 reviews)
"amazing place to stay "
United States
Haylee Ryan
The price is ₩182,830
₩212,905 total
includes taxes & fees
May 10 - May 11
The Revolution Hotel

Hyatt Centric Faneuil Hall Boston

Hyatt Centric Faneuil Hall Boston
4.0 star property
Boston Financial District, 4.4 km from Medical Center Area
9.2 out of 10, Wonderful, (1,354 reviews)
"Excellent location and great hotel. "
United States
Jessica
The price is ₩267,413
₩370,374 total
includes taxes & fees
May 25 - May 26
Hyatt Centric Faneuil Hall Boston

The Westin Boston Seaport District

The Westin Boston Seaport District
4.0 star property
Seaport District, 5 km from Medical Center Area
9.2 out of 10, Wonderful, (2,411 reviews)
"Great hotel!"
United States
Andrea
The price is ₩277,903
₩392,437 total
includes taxes & fees
May 8 - May 9
The Westin Boston Seaport District

The Godfrey Hotel Boston

The Godfrey Hotel Boston
4.0 star property
Downtown Crossing, 3.9 km from Medical Center Area
9.4 out of 10, Exceptional, (5,034 reviews)
"Great hotel!"
United States
Luis Javier
The price is ₩262,079
₩365,426 total
includes taxes & fees
May 10 - May 11
The Godfrey Hotel Boston

The Hotel Salem

The Hotel Salem
3.0 star property
26.6 km from Medical Center Area
9.4 out of 10, Exceptional, (1,004 reviews)
"Nice hotel with very friendly staff, great location"
Canada
allison
The price is ₩255,155
₩285,008 total
includes taxes & fees
May 13 - May 14
The Hotel Salem
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Medical Center Area

Find the best Medical Center Area areas and neighborhoods for the activities you enjoy most.

Downtown Boston

Densely packed with highrise buildings, this area boasts landmarks like Custom House Tower and is close to Quincy Market, Faneuil Hall, and the Old State House. Find headquarters of major banks, hotels, and investment firms here.

Back Bay

Victorian brownstone homes and cultural institutions like the Boston Public Library define this area. Shop at Newbury Street, Prudential Center, and Copley Place, or explore sights like Trinity Church and the John Hancock Tower.

Seaport District

Experience a transformed industrial area with office towers, innovation labs, and 78 restaurants. Visit the Institute of Contemporary Art and easily access Downtown Boston via the Evelyn Moakley Bridge.

Beacon Hill

Historic Federal-style rowhouses, gaslit streets, and brick sidewalks create a charming atmosphere. Explore the Boston African American National Historic Site, shop on Charles Street, and easily access MBTA stations.

Fenway–Kenmore

Home to Fenway Park and the Museum of Fine Arts, this vibrant area boasts numerous educational institutions, cultural attractions, and independent shops. Easily accessible via MBTA subway and bus lines, explore Kenmore Square and admire the iconic Citgo sign.

Top Medical Center Area Hotel Reviews

Frequently asked questions

What's it like in Medical Center Area?
Guests are sure to enjoy their time checking out all that Boston's Medical Center Area neighborhood has to offer. Be sure to check out Isabella Stewart Gardner Museum and Warren Anatomical Museum as part of your Medical Center Area travel plans.
What's a favorite hotel to stay in Medical Center Area?
Based on Expedia customer reviews, The Inn at Longwood Medical is the highest ranked property in Medical Center Area. This hotel is a short 1-minute walk from Boston Children's Hospital, and it offers a restaurant and a fitness center.
How many hotels are there in Medical Center Area?
When you want to kick up your feet after a day of exploring the sights in Boston, you can choose from 17 Expedia hotels and other accommodations in Medical Center Area.
If I need to cancel my hotel reservation in Medical Center Area, will I receive a refund?
Yes, most hotel room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to get the best deals available in Medical Center Area.
Where can I learn more about changing or cancelling my trip to Medical Center Area?
For more information about updating your trip to Medical Center Area or cancelling it, go to https://www.expedia.com/service/.
What can I see and do in this Boston neighborhood?
Sights like Isabella Stewart Gardner Museum and Warren Anatomical Museum can be part of your cultural tour of Medical Center Area. When you're sightseeing in Boston, Fenway Park and Copley Square are also worth a stop.
How can I get around Medical Center Area and the greater Boston area?
If you want to see more of the city, Longwood Medical Area Station is the closest metro stop. Others nearby include Brigham Circle Station and Museum of Fine Arts Station.