Mesa County Vacations & Trips

Book a Hotel + Flight or Car together to unlock savings

Photo by Ron McKenzie

  • Plan, book, travel with confidence

  • Better together

    Save up to ₩234,741 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Top destinations in Mesa County

An old train station at Grand Junction, Colorado. A great place to let out the train-spotting nerd in you - you know it's in there!
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Grand Junction

Grand Junction

Mesa County Hotel Deals

Grand Vista Hotel

Grand Vista Hotel

3.5 out of 5
2790 Crossroads Blvd Grand Junction CO
Fully refundableReserve now, pay when you stay
8.2/10 Very Good! (3,483 reviews)
Good

Reviewed on Jan 19, 2026

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Grand Vista Hotel
La Quinta Inn & Suites by Wyndham Grand Junction

La Quinta Inn & Suites by Wyndham Grand Junction

3 out of 5
2761 Crossroads Blvd Grand Junction CO
Fully refundableReserve now, pay when you stay
The price is ₩104,400 per night from Jan 25 to Jan 26
₩104,400
₩119,700 total
Jan 25 - Jan 26
includes taxes & fees
8.6/10 Excellent! (2,776 reviews)
Clean room

Reviewed on Jan 17, 2026

La Quinta Inn & Suites by Wyndham Grand Junction
Pet-friendly Grand Junction Townhome w/ Yard!

Pet-friendly Grand Junction Townhome w/ Yard!

3.5 out of 5
Grand Junction CO
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Pet-friendly Grand Junction Townhome w/ Yard!
See all 624 properties in Mesa County
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Mesa County vacation package cost?
Starting from as little as , you can customize your Mesa County vacation package. Simply bundle hotels, flights and car rentals and be rewarded with discounts.
How do I get a cheap travel package to Mesa County?
Booking a Mesa County vacation package with Expedia is one of the best ways to save. We have more than 550 partner airlines and 1,000,000 hotels all over the world. With such a fantastic range to pick from, you'll have no issues putting together your dream getaway.
What are the top hotels in Mesa County?
When it comes to hotels in Mesa, Grand Vista Hotel and La Quinta Inn & Suites by Wyndham Grand Junction are a couple of favorites. If you're also spending time in Collbran, Days Inn by Wyndham Grand Junction and Ramada by Wyndham Grand Junction look forward to welcoming you.
How far in advance should I book my Mesa County vacation?
While prices change frequently, we generally recommend booking your flight as early as possible. Most international fares are found on Expedia up to a year in advance. If circumstances have left you booking late, you might still be in luck. Cheaper tickets to Mesa County occasionally appear in the weeks prior to departure.
What does an Expedia Mesa County travel package include?
With Expedia, you can select any combination of car rentals, flights and hotels to create your ideal Mesa County package. Once you've made your booking, you can add on all the fun stuff like sightseeing tours and activities. Remember, the more you bundle, the bigger the savings!
What should I know before booking a Mesa County travel package?
Bundling your bookings into a Mesa County vacation package is the most convenient way to organize your trip. Not only that, you'll get great discounts when you combine your flights, hotels and car rentals. Once you've booked, why not add on an activity or a tour?
Can I choose my airline with a Mesa County Expedia vacation package?
Yes — that's the beauty of an Expedia vacation package. You're in charge! We have access to more than 550 partner airlines throughout the world, so you have loads of choice when organizing your Mesa County getaway.
If I'm not able to travel, can I cancel my Mesa County vacation package?
We get that sometimes life doesn't go according to plan. If you've locked in a Mesa County vacation package and need to change or cancel it, we're here to help. We recommend looking up our Customer Service Portal first for information. But generally speaking, if you've booked your package in the last 24 hours, you may be able to cancel or change your itinerary free of charge. If it's been more than 24 hours, your hotel, airline or car rental company may charge a fee.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.