Mesa County Vacations & Trips

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Top destinations in Mesa County

A river winding through a valley with a large solar farm and a mountain in the background.
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Grand Junction

Grand Junction
A canyon with layered rock formations and distant mountains.
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Gateway

Gateway

Mesa County Hotel Deals

Grand Vista Hotel

Grand Vista Hotel

3.5 out of 5
2790 Crossroads Blvd Grand Junction CO
Fully refundableReserve now, pay when you stay
The price is ₩116,574 per night from Jul 28 to Jul 29
₩116,574
₩133,665 total
Jul 28 - Jul 29
includes taxes & fees
Grand Vista Hotel
Ramada by Wyndham Grand Junction

Ramada by Wyndham Grand Junction

2.5 out of 5
752 Horizon Dr Grand Junction CO
Fully refundableReserve now, pay when you stay
The price is ₩105,520 per night from Jul 29 to Jul 30
₩105,520
₩120,989 total
Jul 29 - Jul 30
includes taxes & fees
8.2/10 Very Good! (1,960 reviews)
"The customer service was great, very friendly staff, both the front desk people and the cleaning staff. Friendly and engaging. Pool was wonderful, especially on the scorching hot days. Advertised a hot tub, and there was no hot tub."

Reviewed on Jul 26, 2026

Ramada by Wyndham Grand Junction
La Quinta Inn & Suites by Wyndham Grand Junction

La Quinta Inn & Suites by Wyndham Grand Junction

3 out of 5
2761 Crossroads Blvd Grand Junction CO
Fully refundableReserve now, pay when you stay
The price is ₩166,764 per night from Aug 23 to Aug 24
₩166,764
₩191,202 total
Aug 23 - Aug 24
includes taxes & fees
8.8/10 Excellent! (2,862 reviews)
"Our go to hotel now when we visit our son at CMU!! Clean, roomy, and comfortable beds."

Reviewed on Jul 27, 2026

La Quinta Inn & Suites by Wyndham Grand Junction
See all 628 properties in Mesa County
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Mesa County vacation package cost?
Starting from as little as , you can customize your Mesa County vacation package. Simply bundle hotels, flights and car rentals and be rewarded with discounts.
How do I get a cheap travel package to Mesa County?
Booking a Mesa County vacation package with Expedia is one of the best ways to save. We have more than 550 partner airlines and 1,000,000 hotels all over the world. With such a fantastic range to pick from, you'll have no issues putting together your dream getaway.
What are the top hotels in Mesa County?
When it comes to hotels in Mesa, Grand Vista Hotel and La Quinta Inn & Suites by Wyndham Grand Junction are a couple of favorites. If you're also spending time in Collbran, Days Inn by Wyndham Grand Junction and Ramada by Wyndham Grand Junction look forward to welcoming you.
How far in advance should I book my Mesa County vacation?
While prices change frequently, we generally recommend booking your flight as early as possible. Most international fares are found on Expedia up to a year in advance. If circumstances have left you booking late, you might still be in luck. Cheaper tickets to Mesa County occasionally appear in the weeks prior to departure.
What does an Expedia Mesa County travel package include?
With Expedia, you can select any combination of car rentals, flights and hotels to create your ideal Mesa County package. Once you've made your booking, you can add on all the fun stuff like sightseeing tours and activities. Remember, the more you bundle, the bigger the savings!
What should I know before booking a Mesa County travel package?
Bundling your bookings into a Mesa County vacation package is the most convenient way to organize your trip. Not only that, you'll get great discounts when you combine your flights, hotels and car rentals. Once you've booked, why not add on an activity or a tour?
Can I choose my airline with a Mesa County Expedia vacation package?
Yes — that's the beauty of an Expedia vacation package. You're in charge! We have access to more than 550 partner airlines throughout the world, so you have loads of choice when organizing your Mesa County getaway.
If I'm not able to travel, can I cancel my Mesa County vacation package?
We get that sometimes life doesn't go according to plan. If you've locked in a Mesa County vacation package and need to change or cancel it, we're here to help. We recommend looking up our Customer Service Portal first for information. But generally speaking, if you've booked your package in the last 24 hours, you may be able to cancel or change your itinerary free of charge. If it's been more than 24 hours, your hotel, airline or car rental company may charge a fee.

Stay near popular Mesa County attractions

A snowy forest with tall trees covered in snow.
Photo by Craig Droskin
Open Photo by Craig Droskin

Powderhorn Resort

8.6/10 (106 reviews)
Hit the slopes at Powderhorn Resort during your trip to Mesa. Check out the wineries or top-notch restaurants in this romantic area.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.