Find Gay friendly Hotels in Otay Mesa West, CA

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Check availability on Otay Mesa West Gay friendly Hotels

Our top choices for Otay Mesa West LGBT-friendly hotels

3 outdoor pools, cabanas (surcharge), pool umbrellas
Sycuan Casino Resort

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
El Cajon
9.2 out of 10, Wonderful, (1627)
"Nice hotel and friendly staff. Will definitely stay again ."
United States
Lorna
Sycuan Casino Resort
Suite, 1 King Bed with Sofa Bed (Marina Tower Newly Renovated Marina view) | View from room
Sheraton San Diego Resort

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
Harbor Island
8.2 out of 10, Very Good, (3173)
"Great stay! "
United States
Melissa
The price is ₩138,201
₩211,782 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Sheraton San Diego Resort
Exterior
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay
8.4 out of 10, Very Good, (1570)
"Loved our stay "
United States
Jeremy
The price is ₩170,692
₩273,991 total
includes taxes & fees
Dec 18 - Dec 19
Hyatt Regency Mission Bay Spa and Marina
Standard Room, 1 King Bed, Non Smoking, Bay View | Premium bedding, pillowtop beds, in-room safe, desk
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (726)
"Great little boutique hotel ! Friendly staff as well"
Canada
Caroll
The price is ₩143,726
₩166,642 total
includes taxes & fees
Dec 14 - Dec 15
The DEXTRO Little Italy, BW Premier Collection
Outdoor pool, sun loungers
Hilton San Diego Bayfront

Hilton San Diego Bayfront

Hilton San Diego Bayfront
4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1856)
"Enjoyed my stay"
United States
Brandon
The price is ₩138,465
₩232,451 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hilton San Diego Bayfront
Outdoor pool
Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
Mission Valley
7.8 out of 10, Good, (1010)
"Good value Nice place to stay "
United States
John
The price is ₩124,545
₩143,779 total
includes taxes & fees
Dec 14 - Dec 15
Crowne Plaza San Diego - Mission Valley by IHG
Terrace/patio
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley
2.5 star property
Mission Valley
8.8 out of 10, Excellent, (1275)
"Room was clean,buffet bkfast was good,staff were friendly & helpful!"
United States
Barry
The price is ₩143,493
₩164,929 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hampton Inn San Diego/Mission Valley
Premium bedding, pillowtop beds, desk, laptop workspace
Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1000)
"Great location "
United States
Mohammad
The price is ₩165,400
₩234,262 total
includes taxes & fees
Dec 30 - Dec 31
Staypineapple, Hotel Z, Gaslamp San Diego
2 outdoor pools, open 6 AM to 10:00 PM, cabanas (surcharge)
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (1942)
"Great hotel"
United States
Farzana
The price is ₩232,973
₩347,177 total
includes taxes & fees
Dec 21 - Dec 22
Marriott Marquis San Diego Marina
Reception
Kings Inn San Diego

Kings Inn San Diego

Kings Inn San Diego
2.5 star property
Mission Valley
8.8 out of 10, Excellent, (3562)
"Room was very clean, and the breakfast was good"
United States
Roxana
The price is ₩109,695
₩125,875 total
includes taxes & fees
Dec 17 - Dec 18
Kings Inn San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Otay Mesa West Hotel Reviews

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Frequently asked questions

How do I find an LGBTQ-friendly hotel in Otay Mesa West?
If you're searching for a place where you'll feel welcome in Otay Mesa West, our website has the LGBTQ-friendly hotel you're looking for. Discover the people, places, and traditions found only in Otay Mesa West.
What should I do while I'm visiting Otay Mesa West?
During your trip, get out and explore everything Otay Mesa West is known for. You and your traveling companions may want to visit San Diego Zoo, San Ysidro Border Crossing, and Petco Park. While you're here, capture some great memories of your trip with stops at Port of San Diego and Mission Bay.
What is a gay-friendly hotel in Otay Mesa West?
LGBTQ-friendly hotels are places where lesbian, gay, bisexual, and transgender travelers are proudly welcomed. Expedia has compiled a selection of LGBTQ-friendly hotels worldwide. In Otay Mesa West, these hotels operate in a spirit of inclusiveness, prioritizing a diverse environment in which guests are welcomed, respected, and not obliged to declare or hide their sexual orientation.
What can I expect from a gay-friendly hotel in Otay Mesa West?
Stay at a gay-friendly hotel in Otay Mesa West and the staff will help you explore the local gay scene and the LGBTQ+ culture. Some of Expedia's LGBTQ-friendly hotels go the extra mile and offer wedding ceremonies and honeymoon packages for same-sex couples.