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Our top choices for Sanctuary On Spruce Creek hotels

Exterior
Daytona Grande Oceanfront Resort

Daytona Grande Oceanfront Resort

Daytona Grande Oceanfront Resort
4.0 star property
17 km from Sanctuary On Spruce Creek
9.2 out of 10, Wonderful, (4272)
"Wonderful place to stay "
United States
Stacey
The price is ₩148,383
₩215,587 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Daytona Grande Oceanfront Resort
Room, Terrace, Oceanfront | Premium bedding, pillowtop beds, in-room safe, individually decorated
The Shores Resort & Spa

The Shores Resort & Spa

The Shores Resort & Spa
4.0 star property
12 km from Sanctuary On Spruce Creek
9.0 out of 10, Wonderful, (1704)
"Overall stay its a great resort hotel"
United States
Elijah
The price is ₩188,789
₩268,666 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The Shores Resort & Spa
Outdoor pool, open 7:00 AM to 10:00 PM, cabanas (surcharge)
Delta Hotels by Marriott Daytona Beach

Delta Hotels by Marriott Daytona Beach

Delta Hotels by Marriott Daytona Beach
3.5 star property
12.5 km from Sanctuary On Spruce Creek
9.2 out of 10, Wonderful, (1002)
"Great location, staff and amenities"
United States
JOSEPH ANDREW
The price is ₩170,418
₩191,720 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Delta Hotels by Marriott Daytona Beach
View from property
Nautilus Inn

Nautilus Inn

Nautilus Inn
2.5 star property
14.4 km from Sanctuary On Spruce Creek
9.2 out of 10, Wonderful, (3043)
"Just a nice, clean and friendly place to stay "
United States
sohrab
The price is ₩140,251
₩157,783 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Nautilus Inn
2 outdoor pools, pool umbrellas, sun loungers
Hilton Daytona Beach Oceanfront Resort

Hilton Daytona Beach Oceanfront Resort

Hilton Daytona Beach Oceanfront Resort
4.0 star property
16.5 km from Sanctuary On Spruce Creek
7.4 out of 10, Good, (4989)
"Great stay"
United States
ashley
The price is ₩184,429
₩247,700 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hilton Daytona Beach Oceanfront Resort
2 outdoor pools, a heated pool, pool umbrellas, sun loungers
Hard Rock Hotel Daytona Beach

Hard Rock Hotel Daytona Beach

Hard Rock Hotel Daytona Beach
4.0 star property
17.8 km from Sanctuary On Spruce Creek
9.2 out of 10, Wonderful, (1640)
"Location of our room and friendliness of staff."
United States
Steven
The price is ₩213,318
₩302,717 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hard Rock Hotel Daytona Beach
Outdoor pool
Days Inn by Wyndham Daytona Oceanfront

Days Inn by Wyndham Daytona Oceanfront

Days Inn by Wyndham Daytona Oceanfront
2.5 star property
10 km from Sanctuary On Spruce Creek
8.6 out of 10, Excellent, (1967)
"Great place to stay "
United States
Kathy
The price is ₩108,155
₩134,533 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Days Inn by Wyndham Daytona Oceanfront
Outdoor pool, a heated pool, pool umbrellas, sun loungers
Bahama House

Bahama House

Bahama House
3.0 star property
13.9 km from Sanctuary On Spruce Creek
9.2 out of 10, Wonderful, (1849)
"Great place , great location , super friendly staff Highly recommended "
United States
Robert
Bahama House
Poolside Cabana | Living area | 46-inch LED TV with cable channels, TV
The Riverview Hotel

The Riverview Hotel

The Riverview Hotel
3.0 star property
13.6 km from Sanctuary On Spruce Creek
9.4 out of 10, Exceptional, (959)
"Great location and friendly staff."
United States
PAMELA R
The price is ₩243,189
₩289,668 total
includes taxes & fees
Jan 5 - Jan 6, 2026
The Riverview Hotel
View from property
Coral Sands Inn

Coral Sands Inn

Coral Sands Inn
2.5 star property
26.1 km from Sanctuary On Spruce Creek
9.4 out of 10, Exceptional, (1280)
"Great property, rooms and view "
United States
Amanda
The price is ₩120,951
₩136,070 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Coral Sands Inn
Sundeck
The Salty Mermaid Oceanfront Hotel

The Salty Mermaid Oceanfront Hotel

The Salty Mermaid Oceanfront Hotel
2.5 star property
14.4 km from Sanctuary On Spruce Creek
9.6 out of 10, Exceptional, (387)
"Loved the retro motel feel with a modern decor and amenities. The direct access to the beach was fabulous!"
United States
Martha
The price is ₩227,319
₩284,335 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The Salty Mermaid Oceanfront Hotel
Exterior
Holiday Inn Express & Suites Oceanfront by IHG

Holiday Inn Express & Suites Oceanfront by IHG

Holiday Inn Express & Suites Oceanfront by IHG
2.5 star property
10.2 km from Sanctuary On Spruce Creek
8.0 out of 10, Very Good, (1153)
"Staff was very nice and loved the location. "
United States
Iramaris
The price is ₩140,109
₩157,622 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Holiday Inn Express & Suites Oceanfront by IHG
Property amenity
SpringHill Suites by Marriott New Smyrna Beach

SpringHill Suites by Marriott New Smyrna Beach

SpringHill Suites by Marriott New Smyrna Beach
2.5 star property
14.1 km from Sanctuary On Spruce Creek
9.0 out of 10, Wonderful, (856)
"Fantastic location, great property, super staff!"
United States
Helene
The price is ₩256,056
₩288,063 total
includes taxes & fees
Jan 13 - Jan 14, 2026
SpringHill Suites by Marriott New Smyrna Beach
Outdoor pool, sun loungers
Holiday Inn Resort Daytona Beach Oceanfront by IHG

Holiday Inn Resort Daytona Beach Oceanfront by IHG

Holiday Inn Resort Daytona Beach Oceanfront by IHG
3.0 star property
14.3 km from Sanctuary On Spruce Creek
7.8 out of 10, Good, (1002)
"Yes, we had breakfast outside this morning, it was great. Also checking in was a breeze, man at the desk was professional, personable and had a great smile the whole time. We come back here year after year, good to see Shannon is still here ."
United States
Kevin
The price is ₩120,093
₩177,994 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Resort Daytona Beach Oceanfront by IHG
Exterior
Boardwalk Inn and Suites

Boardwalk Inn and Suites

Boardwalk Inn and Suites
2.5 star property
15.7 km from Sanctuary On Spruce Creek
8.4 out of 10, Very Good, (1615)
"Great stay."
United States
JOHN
Boardwalk Inn and Suites
Room, 2 Queen Beds, Accessible, Pool View (Hearing) | Pool | Outdoor pool
Hilton Garden Inn Daytona Beach Oceanfront

Hilton Garden Inn Daytona Beach Oceanfront

Hilton Garden Inn Daytona Beach Oceanfront
3.0 star property
20.1 km from Sanctuary On Spruce Creek
8.4 out of 10, Very Good, (1011)
"Rooms was clean, the staff was very friendly "
United States
Angela
The price is ₩146,660
₩164,994 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Hilton Garden Inn Daytona Beach Oceanfront
Terrace/patio
Hampton Inn New Smyrna Beach

Hampton Inn New Smyrna Beach

Hampton Inn New Smyrna Beach
2.5 star property
13.7 km from Sanctuary On Spruce Creek
8.6 out of 10, Excellent, (1003)
"Clean room, friendly staff, convenience to shopping and dining!"
United States
ron
The price is ₩174,678
₩196,513 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Hampton Inn New Smyrna Beach
Poolside bar
Perry's Ocean Edge Resort

Perry's Ocean Edge Resort

Perry's Ocean Edge Resort
2.5 star property
13.3 km from Sanctuary On Spruce Creek
8.4 out of 10, Very Good, (2356)
"Clean large room, comfortable bed, friendly staff. "
United States
D'Ann
The price is ₩170,332
₩224,048 total
includes taxes & fees
Jan 28 - Jan 29, 2026
Perry's Ocean Edge Resort
Exterior
Country Inn & Suites by Radisson, Port Orange-Daytona, FL

Country Inn & Suites by Radisson, Port Orange-Daytona, FL

Country Inn & Suites by Radisson, Port Orange-Daytona, FL
2.5 star property
2.7 km from Sanctuary On Spruce Creek
8.8 out of 10, Excellent, (1009)
"Would stay here again "
United States
Manuel
The price is ₩138,965
₩156,335 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Country Inn & Suites by Radisson, Port Orange-Daytona, FL
Outdoor pool, open 9:00 AM to 10:00 PM, sun loungers
Best Western New Smyrna Beach Hotel & Suites

Best Western New Smyrna Beach Hotel & Suites

Best Western New Smyrna Beach Hotel & Suites
3.0 star property
15.2 km from Sanctuary On Spruce Creek
8.0 out of 10, Very Good, (1000)
"Huge room fabulous views"
United States
elizabeth
The price is ₩198,997
₩223,871 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Best Western New Smyrna Beach Hotel & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Sanctuary On Spruce Creek

Find the best Sanctuary On Spruce Creek areas and neighborhoods for the activities you enjoy most.

Carter Norwood

While there might not be top attractions in Carter Norwood, you can explore the larger area and discover places like Ponce de Leon Inlet Lighthouse and Museum and Pirate's Island Adventure Golf.

Winthrop Holding

If you're looking for some top things to see and do in Winthrop Holding and surrounding area, you can visit Ponce de Leon Inlet Lighthouse and Museum and Dahlia Avenue Park.

Halifax Estates

While Halifax Estates isn't home to many top sights, Ponce de Leon Inlet Lighthouse and Museum and Pirate's Island Adventure Golf are some notable places to visit nearby.

Harbor Oaks

Though Harbor Oaks might not have many top sights, you can venture to the surrounding area to see attractions like Go-Kart City and Ponce Inlet Beach.

Fly In Spruce Creek

If you're looking for some top things to see and do in Fly In Spruce Creek and surrounding area, you can visit Spruce Creek Country Club and Crane Lakes Golf and Country Club.

Top Sanctuary On Spruce Creek Hotel Reviews

Perry's Ocean Edge Resort

Perry's Ocean Edge Resort

10/10 Excellent
"I really enjoyed my stay, enjoyed mi view the hospitality and the convenience of how everything was close. I will be back."
Jennifer 3-night trip
Posted 2 days ago
Perry's Ocean Edge Resort

Frequently asked questions

What is Sanctuary On Spruce Creek like?
Travelers to the Sanctuary On Spruce Creek neighborhood in Port Orange will be sure to enjoy their stay.
If I need to cancel my hotel reservation in Sanctuary On Spruce Creek, will I receive a refund?
Yes! The majority of room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then filter by "fully refundable" to view the top deals on offer in Sanctuary On Spruce Creek.
Where can I learn more about changing or cancelling my trip to Sanctuary On Spruce Creek?
For more information about picking new dates or cancelling your trip to Sanctuary On Spruce Creek, head over to our customer service page.
What is there to do in this Port Orange neighborhood?
Gamble Place, Spruce Creek Country Club, and Airport Road Park are just a few of the places to visit in and around Sanctuary On Spruce Creek. Golf Club at Cypress Head and Crane Lakes Golf and Country Club are also worth a visit when you're out sightseeing in Port Orange.