Find Boutique Hotels in Southwest Ohio, OH

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Check availability on Southwest Ohio Boutique Hotels

Tonight
Dec 26 - Dec 27
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Dec 27 - Dec 28
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Dec 26 - Dec 28
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Jan 2 - Jan 4

Our top choices for Southwest Ohio boutique hotels

Egyptian cotton sheets, premium bedding, in-room safe, laptop workspace
21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati
4.5 star property
Downtown Cincinnati
8.6 out of 10, Excellent, (1004)
"Pleasant stay"
United States
Tim
The price is ₩219,637
₩269,249 total
includes taxes & fees
Jan 1 - Jan 2, 2026
21c Museum Hotel Cincinnati
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southwest Ohio Hotel Reviews

21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati

10/10 Excellent
"Wine at the bar was super expensive for two glasses. Otherwise, everything was great!"
Stacey 1-night trip
Posted 6 days ago
21c Museum Hotel Cincinnati