Upstate South Carolina, South Carolina hotel rooms at the Motel 6
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check prices for these dates
Compare rooms and suites by Motel 6 in Upstate South Carolina with rates, reviews, and availability. Most hotels are fully refundable.

Motel 6 Spartanburg, Sc – Northwest / Business 85
Motel 6 Spartanburg, Sc – Northwest / Business 85
7.2 out of 10, Good, (57)
The price is ₩105,879
₩117,527 total
includes taxes & fees
Jul 11 - Jul 12

Motel 6 Simpsonville, SC - Greenville
Motel 6 Simpsonville, SC - Greenville
7.2 out of 10, Good, (334)
The price is ₩96,252
₩105,879 total
includes taxes & fees
Jul 11 - Jul 12

Motel 6 Greenville, SC
Motel 6 Greenville, SC
5.0 out of 10, (621)

Motel 6 Greenville, SC - I-85 Near Downtown
Motel 6 Greenville, SC - I-85 Near Downtown
6.6 out of 10, (280)
The price is ₩96,266
₩105,893 total
includes taxes & fees
Aug 3 - Aug 4
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Recent reviews of Upstate South Carolina hotels
Recent reviews of Upstate South Carolina hotels

La Quinta Inn & Suites by Wyndham Greenville Haywood
5/5 Excellent
"Great place for relaxation!"
A verified traveler from Taylors stayed at La Quinta Inn & Suites by Wyndham Greenville Haywood
Posted 1 day ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Upstate South Carolina Hotels by Brand
Hotels in Upstate South Carolina Neighborhoods
Hotels near popular Upstate South Carolina Attractions
More Hotel Options in Upstate South Carolina
- Adults Only Resorts & Hotels in Upstate South Carolina
- Adventure Hotels in Upstate South Carolina
- Beach Hotels in Upstate South Carolina
- Boutique Hotels in Upstate South Carolina
- Business Hotels in Upstate South Carolina
- Cheap Hotels in Upstate South Carolina
- Family Hotels in Upstate South Carolina
- Golf Hotels in Upstate South Carolina
- Historic Hotels in Upstate South Carolina
- Hotel Wedding Venues in Upstate South Carolina
- Hotel with a Concierge in Upstate South Carolina
- Hotels with Bars in Upstate South Carolina
- Hotels with Early Check-in in Upstate South Carolina
- Hotels with Free Parking in Upstate South Carolina
- Hotels with Hot Tubs in Upstate South Carolina
- Hotels with WiFi in Upstate South Carolina
- Hotels with a Pool in Upstate South Carolina
- Hotels with an Indoor Pool in Upstate South Carolina
- Hotels with smoking rooms in Upstate South Carolina
- Luxury Hotels in Upstate South Carolina
- Pet-friendly Hotels in Upstate South Carolina
- Resorts & Hotels with Spas in Upstate South Carolina
- Romantic Hotels in Upstate South Carolina
- Shopping Hotels in Upstate South Carolina
- Ski Hotels in Upstate South Carolina