A bench, a bicycle, and a lake surrounded by trees.

Upstate South Carolina, South Carolina hotel rooms at the Red Roof Inn

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Oct 16 - Oct 17
Tomorrow
Oct 17 - Oct 18
This weekend
Oct 16 - Oct 18
Next weekend
Oct 23 - Oct 25

Our top choices for Upstate South Carolina Red Roof Inn

A hotel room with a bed, a sofa, a desk, a chair, a lamp, and a bathroom visible through an open door.
A modern hotel lobby with a large arched window, a Red Roof Inn sign, a flat-screen TV, and a self-service kiosk.
A coffee station with a coffee machine, cups, and condiments.
A bathroom with a bathtub, sink, mirror, toilet, and handrails.

1. Red Roof Inn & Suites Duncan

Red Roof Inn & Suites Duncan
Duncan
United States
Denise
₩91,724
₩103,190 total
includes taxes & fees
Nov 2 - Nov 3
Red Roof Inn & Suites Duncan
A hotel room with two beds, a nightstand, a lamp, a chair, and a window with curtains.
A Red Roof Inn Registration Office with a red awning and a sign indicating the office.
A guest laundry area with two washing machines and a sign indicating the location.
A Red Roof Inn reception area with a stone wall, two leather chairs, a small table, and a reception desk.

2. Red Roof Inn Spartanburg – I-26

Red Roof Inn Spartanburg – I-26
Spartanburg
United States
patti-jo
₩82,004
₩91,024 total
includes taxes & fees
Oct 31 - Nov 1
Red Roof Inn Spartanburg – I-26
A hotel reception area with a red sign indicating free Wi-Fi in all rooms, a control panel, a laptop, and a payment terminal.
A vending machine with snacks and a drink dispenser.
A hotel with a red sign reading 'Red Roof Inn & Suites' and a two-story structure with multiple windows and balconies.
A conference room with a table, chairs, a sofa, a wall-mounted light, and an air conditioning unit.

3. Red Roof Inn Spartanburg - I-85

Red Roof Inn Spartanburg - I-85
Spartanburg
United States
Walker
₩87,152
₩96,740 total
includes taxes & fees
Oct 18 - Oct 19
Red Roof Inn Spartanburg - I-85
A hotel room with a bed, a TV, a desk, and a microwave.
A restaurant with red chairs and a counter with food items.
A multi-story building with a covered parking area.
Two vending machines, one with a Pepsi logo and the other with a FreshChoices label.

4. Red Roof Inn Gaffney

Red Roof Inn Gaffney
Gaffney
United States
Belinda
₩83,533
₩93,557 total
includes taxes & fees
Oct 25 - Oct 26
Red Roof Inn Gaffney
A hotel room with a large bed, a television, a desk with a computer, and a mirror.
A vending machine with snacks and a separate cold drink machine.
A hotel with a parking lot, a sign for 'Red Roof Inn', and a sunset sky.
A room with a stone wall, two red chairs, a small table, and a window with blinds.

5. Red Roof Inn Greenville

Red Roof Inn Greenville
Greenville
United States
ROBERT
₩77,833
₩85,617 total
includes taxes & fees
Nov 2 - Nov 3
Red Roof Inn Greenville
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Top Upstate South Carolina Hotel Reviews

Greenville Inn and Suites

Greenville Inn and Suites

8/10 Good
"Overall good stay! I would definitely come back the prices are very affordable"
Desiree 2-night trip
Posted 20 hours ago
Greenville Inn and Suites
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

10/10 Excellent
"Been multiple times now. Only issue was there was no lantern this go around so I had to go purchase one but other than that. It was lovely. Love the postcard!"
Anonymous traveler 1-night trip
Posted 23 hours ago
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall

10/10 Excellent
"Clean comfortable room. Affordable price."
Sean 1-night trip
Posted 1 day ago
Comfort Inn Greenville - Haywood Mall
Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa

10/10 Excellent
"Great location."
Anonymous traveler 1-night trip
Posted 2 days ago
Mint House Greenville Downtown by Kasa
Hotel Hartness

Hotel Hartness

10/10 Excellent
"Beautiful property and very friendly staff! Highly recommend!"
Nicole 1-night trip
Posted 2 days ago
Hotel Hartness
Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn

8/10 Good
"The property was in excellent condition. Clean and well maintained. On par with Hilton Garden suites."
Joyce 4-night trip
Posted 2 days ago
Clemson University's James F. Martin Inn
Hampton Inn & Suites Greenville-Downtown-RiverPlace

Hampton Inn & Suites Greenville-Downtown-RiverPlace

8/10 Good
"Ok"
Greg 2-night trip
Posted 2 days ago
Hampton Inn & Suites Greenville-Downtown-RiverPlace

Explore a world of travel with Expedia