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Top Adults Only Gulf Coast Hotels

Shoreline Island Resort - Exclusively Adult

14200 Gulf Boulevard Madeira Beach FL

59 min drive from Port of Tampa

Book a stay at this beach aparthotel in Madeira Beach. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the helpful staff in our reviews. ...

9.2/10 Wonderful! (1,444 reviews)

Room was spotless bedding was exceptional The staff is wonderful this is our 3rd time at the shoreline

Reviewed on Jan 8, 2026

The Southernmost Inn - Adults Only

525 United Street Key West FL

9 hours drive from Port of Tampa

Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...

8.2/10 Very Good! (1,254 reviews)

Great service very nice rooms will go again

Reviewed on Jan 22, 2026

Upper Deck Hotel and Bar - Adults Only

120 E Atol St. South Padre Island TX

Stay at this hotel in South Padre Island. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attractions ...

9.2/10 Wonderful! (171 reviews)

Great entertainment!

Reviewed on Dec 28, 2025

See all 182,949 properties in Gulf Coast

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.