Southeastern United States Adults Only Vacations

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Top Adults Only Southeastern United States Hotels

Shoreline Island Resort - Exclusively Adult

Shoreline Island Resort - Exclusively Adult

3 out of 5
14200 Gulf Boulevard Madeira Beach FL
  • 4 hours drive from Walt Disney World® Resort
Book a stay at this beach aparthotel in Madeira Beach. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,448 reviews)
View from our room was amazing! having the pool and the beach right there, we loved it! The bed was super soft! Front desk staff was so friendly and helpful. Highly recommend!!!!

Reviewed on Feb 1, 2026

Shoreline Island Resort - Exclusively Adult
The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only

3 out of 5
525 United Street Key West FL
  • 11 hours drive from Walt Disney World® Resort
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.2/10 Very Good! (1,275 reviews)
Really chill place with pools and hot tub partially shaded by tropical trees and palms. Along with historic Key West style inn, has a great vibe. Only a block or so from Duval Street, Hemingway. Good breakfast and happy hour. Had a bare bones room (attic suite) and it was just that but never in my ...

Reviewed on Feb 8, 2026

The Southernmost Inn - Adults Only
Paradise Inn Key West - Adults Only

Paradise Inn Key West - Adults Only

3.5 out of 5
819 Simonton Street Key West FL
  • 11 hours drive from Walt Disney World® Resort
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, parking (surcharge), and daily housekeeping. Our guests praise the breakfast and ...
9/10 Wonderful! (1,001 reviews)
Great location, clean modern king suites, awesome staff, wonderful amenities. Highky recommend.

Reviewed on Feb 5, 2026

Paradise Inn Key West - Adults Only
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.