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Top Kid friendly Southeast Missouri Hotels

Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Miner Sikeston MO

4 hours drive from Johnson's Shut-ins State Park

Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Best Western Plus Sikeston I-55

120 S Interstate Drive Sikeston MO

4 hours drive from Johnson's Shut-ins State Park

Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...

8.4/10 Very Good! (1,008 reviews)

"The room was big enough for three adults. The pool was nice and relaxing. My husband especially liked the breakfast as they served biscuits and gravy. We would definitely book this hotel again if the need arises."

Reviewed on Jul 29, 2026

Drury Inn & Suites Cape Girardeau

3303 Campster Drive Cape Girardeau MO

4 hours drive from Johnson's Shut-ins State Park

Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...

See all 681 properties in Southeast Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.