Find hotels in Southeast Missouri, MO from ₩72,470

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Sep 15 - Sep 16
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Compare 604 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Our top choices for Southeast Missouri hotels

Postcard Cabins St. Francois
Exterior

Postcard Cabins St. Francois

2.0 star property
10.0 out of 10, Exceptional, (30)
"Peaceful, beautiful stay. "
The price is ₩105,431
₩165,930 total
includes taxes & fees
Sep 21 - Sep 22
Postcard Cabins St. Francois
Super 8 by Wyndham Farmington
Exterior

Super 8 by Wyndham Farmington

2.0 star property
8.0 out of 10, Very Good, (588)
"Location "
The price is ₩82,923
₩94,408 total
includes taxes & fees
Sep 21 - Sep 22
Super 8 by Wyndham Farmington
The Farmstead Hotel
Front of property

The Farmstead Hotel

2.5 star property
8.8 out of 10, Excellent, (409)
"Great place. "
The price is ₩119,158
₩205,195 total
includes taxes & fees
Sep 16 - Sep 17
The Farmstead Hotel
Holiday Inn Express & Suites Perryville by IHG
Exterior

Holiday Inn Express & Suites Perryville by IHG

2.5 star property
9.4 out of 10, Exceptional, (504)
"Have stayed here the past 3 years during the Laid Back on I-55 Truck Show! Great place to stay! The breakfast is fantastic!! The staff does not disappoint!! "
The price is ₩132,398
₩151,563 total
includes taxes & fees
Sep 21 - Sep 22
Holiday Inn Express & Suites Perryville by IHG
Drury Inn & Suites Jackson MO
Lobby

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1008)
"Was a clean room, nice staff, good parking "
The price is ₩125,415
₩132,592 total
includes taxes & fees
Sep 21 - Sep 22
Drury Inn & Suites Jackson MO
Pear Tree Inn Cape Girardeau West
Lobby

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1004)
"My room was clean and I was very close to shopping and restaurants. I really enjoyed my stay there."
The price is ₩97,542
₩110,043 total
includes taxes & fees
Sep 18 - Sep 19
Pear Tree Inn Cape Girardeau West
Drury Inn & Suites Cape Girardeau
Business center

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (995)
"Excellent place. Really friendly staff"
The price is ₩125,415
₩141,470 total
includes taxes & fees
Sep 29 - Sep 30
Drury Inn & Suites Cape Girardeau
Baymont Inn and Suites by Wyndham Farmington, MO
Business center

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 star property
8.0 out of 10, Very Good, (1007)
"Great location"
The price is ₩72,470
₩82,508 total
includes taxes & fees
Sep 21 - Sep 22
Baymont Inn and Suites by Wyndham Farmington, MO
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Property amenity

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
8.8 out of 10, Excellent, (616)
"Excellent place to stay. Breakfast was good and staff was friendly. "
The price is ₩110,169
₩119,230 total
includes taxes & fees
Sep 17 - Sep 18
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Super 8 by Wyndham Perryville
Exterior

Super 8 by Wyndham Perryville

2.0 star property
8.4 out of 10, Very Good, (908)
" Love the stay and staff was great "
The price is ₩100,692
₩115,268 total
includes taxes & fees
Sep 17 - Sep 18
Super 8 by Wyndham Perryville
Drury Inn & Suites Hayti Caruthersville
Lobby

Drury Inn & Suites Hayti Caruthersville

3.0 star property
9.4 out of 10, Exceptional, (1001)
"Nice place for a over night stay would recamend."
The price is ₩130,990
₩149,289 total
includes taxes & fees
Sep 21 - Sep 22
Drury Inn & Suites Hayti Caruthersville
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Free buffet breakfast

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

2.5 star property
9.4 out of 10, Exceptional, (681)
"Great place to stay!"
The price is ₩206,262
₩235,861 total
includes taxes & fees
Oct 5 - Oct 6
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Comfort Inn Festus - St Louis South
Lobby sitting area

Comfort Inn Festus - St Louis South

2.5 star property
8.0 out of 10, Very Good, (875)
"The stay and food "
The price is ₩107,800
₩125,964 total
includes taxes & fees
Sep 21 - Sep 22
Comfort Inn Festus - St Louis South
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1005)
"Very nice hotel and nice staff "
The price is ₩125,415
₩141,470 total
includes taxes & fees
Sep 21 - Sep 22
Drury Plaza Hotel Cape Girardeau Conference Center
Pear Tree Inn Cape Girardeau Near the Medical Center
Lobby

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1002)
"Nice place. Good price "
The price is ₩97,542
₩110,043 total
includes taxes & fees
Sep 18 - Sep 19
Pear Tree Inn Cape Girardeau Near the Medical Center
Drury Inn & Suites Sikeston, MO
Property amenity

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1002)
"The pool the happy hour was really nice very relaxed nice activities front desk was very helpful at all times"
The price is ₩125,415
₩144,188 total
includes taxes & fees
Sep 21 - Sep 22
Drury Inn & Suites Sikeston, MO
Festus Inn
Banquet hall

Festus Inn

2.0 star property
6.0 out of 10, (38)
"very friendly staff "
The price is ₩128,217
₩146,616 total
includes taxes & fees
Sep 16 - Sep 17
Festus Inn
Echo Bluff State Park
Front of property

Echo Bluff State Park

2.5 star property
9.4 out of 10, Exceptional, (208)
"Beautiful location & very friendly staff!"
The price is ₩263,402
₩278,482 total
includes taxes & fees
Sep 18 - Sep 19
Echo Bluff State Park
Super 8 by Wyndham Potosi
Standard Room, 1 King Bed | In-room safe, desk, blackout drapes, iron/ironing board

Super 8 by Wyndham Potosi

2.0 star property
7.0 out of 10, Good, (367)
"The room was very good for the price."
The price is ₩73,446
₩80,222 total
includes taxes & fees
Sep 28 - Sep 29
Super 8 by Wyndham Potosi
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Lobby

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

3.0 star property
8.0 out of 10, Very Good, (852)
"I enjoyed my stay. The rooms were clean and the staff was friendly. "
The price is ₩129,123
₩147,653 total
includes taxes & fees
Sep 21 - Sep 22
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Southeast Missouri, MO

Showing deals for:Sep 26 - Sep 28

Image gallery for Arcadia Academy

Shared kitchen

Arcadia Academy

3.0 star property
Arcadia
9.8/10Exceptional (8 reviews)
10% off
Price is ₩170,798
₩370,548 total
includes taxes & fees
Arcadia Academy
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Learn more about Southeast Missouri

Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from Sam A. Baker State Park to K Bridge Recreation Area.

See all hotels in Southeast Missouri

Top Southeast Missouri Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"Allowing the guests to use the gym 24/7; would be extremely appreciated. "
ROBERT 1-night trip
Posted 5 days ago
Drury Plaza Hotel Cape Girardeau Conference Center

More cheap stays in Southeast Missouri

More cheap stays in Southeast Missouri

The Riverview

The Riverview

777 Main St, Cape Girardeau, MO
The price is ₩146,752 per night from Sep 16 to Sep 17
₩146,752
₩165,557 total
Sep 16 - Sep 17
includes taxes & fees
9.2/10 Wonderful! (413 reviews)

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