Ozarks Luxury Vacations

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    Better together
    Save up to ₩234,741 when you book a flight and hotel together*
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    Find the right fit
    With over 300,000 hotels worldwide, it's easy to create a perfect package
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Top Luxury Ozarks Hotels

 The Royal Sonesta Chase Park Plaza St. Louis
The Royal Sonesta Chase Park Plaza St. Louis
4.5 out of 5
212 N Kingshighway, St. Louis, MO
  • 24 min walk from St. Louis Zoo
Treat yourself to some luxurious accommodations at The Royal Sonesta Chase Park Plaza St. Louis, where you can enjoy amenities like pillowtop beds, designer ...
8.8/10 Excellent! (1,008 reviews)
"I recently had the pleasure of staying at the Chase Park Plaza in the Central West End of St. Louis, and as always, it exceeded my expectations! Having stayed here for years, I can confidently say that this hotel is an elegant and rewarding place to stay. The facilities are truly beautiful, combining ..."

Reviewed on Jun 29, 2025

The Royal Sonesta Chase Park Plaza St. Louis
Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
4.5 out of 5
1 Ameristar Blvd, St. Charles, MO
  • 28 min drive from St. Louis Zoo
Stay in the lap of luxury at Ameristar Casino Resort and Spa, where you can enjoy amenities like plush bedding, HDTVs, and more. Notable amenities include a ...
8.2/10 Very Good! (1,005 reviews)
Quick family trip
"Great stay! Friendly staff, quick check in, quiet rooms."

Reviewed on Jul 2, 2025

Ameristar Casino Resort and Spa
The Ritz-Carlton, St. Louis
The Ritz-Carlton, St. Louis
5 out of 5
100 Carondelet Plaza, St. Louis, MO
  • 5 min drive from St. Louis Zoo
Be treated to a luxury stay at The Ritz-Carlton, St. Louis, where you can enjoy amenities like plush bedding, designer toiletries, and more. The restaurant, ...
9.2/10 Wonderful! (536 reviews)
"Overall, our stay was as wonderful as expected. However, I have to state that I was disappointed in 2 things related to the room itself (1416). While the room overall was nice, the couch near the windows showed extreme wear and tear with torn threading along the seams. Quite disappointing for a purported ..."

Reviewed on Jun 17, 2025

The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.