Photo by Southernmost Illinois Tourism Bureau

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Top Adventure Southwest Illinois Hotels

SureStay Hotel by Best Western Whittington Rend Lake

13277 Freeway Lane, Whittington, IL

1 hour drive from Southern Illinois University

Book a stay at this business-friendly hotel in Whittington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

8.8/10 Excellent! (848 reviews)

"The staff is very friendly! We paid a stipend fee for a pet friendly room"

Reviewed on Aug 15, 2025

Hampton Inn Carbondale

2175 Reed Station Pkwy, Carbondale, IL

10 min drive from Southern Illinois University

Book a stay at this business-friendly hotel in Carbondale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

8.4/10 Very Good! (576 reviews)

"The evening we stayed here was move in weekend for SIU and we had moved our son into his apartment. We chose this location for its price and amenities. It was very unfortunate that management chose to shut down the pool and hot tub for routine maintenance this weekend and we could not enjoy the pool ..."

Reviewed on Aug 16, 2025

Days Inn & Suites by Wyndham Caseyville

2423 Old Country Inn Drive, Caseyville, IL

3 hours drive from Southern Illinois University

Book a stay at this business-friendly hotel in Caseyville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pleasant Ridge Park and Cahokia ...

3.8/10 (282 reviews)

"No pool no mini fridge, no microwave in the room"

Reviewed on Aug 10, 2025

See all 698 properties in Southwest Illinois

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.