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Top Luxury Southwest Coast Florida Hotels

Wyvern Hotel, an Ascend Collection Hotel

101 E Retta Esplanade Punta Gorda FL

1 hour drive from Siesta Key Beach

Stay in the lap of luxury at Wyvern Hotel, an Ascend Collection Hotel, where you can enjoy amenities like plush bedding, designer toiletries, and more. Deluxe ...

8.8/10 Excellent! (1,003 reviews)

Lots of noise, halls, traffic.

Reviewed on Jan 17, 2026

Naples Grande Beach Resort

475 Seagate Drive Naples FL

3 hours drive from Siesta Key Beach

Naples Grande Beach Resort is one of the Naples lavish 4.5-star beach properties where you can treat yourself to deep soaking bathtubs and massage services. ...

8.8/10 Excellent! (2,016 reviews)

Nice property. Nice rooms. The beach was easy to access. Only complaint was poor water pressure in my room

Reviewed on Jan 17, 2026

The Ritz-Carlton, Sarasota

1111 Ritz Carlton Dr Sarasota FL

12 min drive from Siesta Key Beach

The Ritz-Carlton, Sarasota is a Sarasota luxury 5-star beach property where you can treat yourself to pillowtop beds, designer toiletries, and more. The 2 outdoor ...

9/10 Wonderful! (999 reviews)

Excellent staff. Wonderful details. Love the shuttle to the amazing private beach club

Reviewed on Jan 11, 2026

See all 46,422 properties in Southwest Coast Florida

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.