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Our top choices for Southwest Coast Florida hotels

A hotel with a modern design, featuring a prominent 'Best Western' sign, multiple parking spaces, and palm trees.

1. Best Western Fort Myers Inn & Suites

Fort Myers

Azael

₩114,282 total

includes taxes & fees

Nov 1 - Nov 2

A kitchen counter with a blue sign, a food allergy card, a pancake maker, and a sign that says 'OH, FLIP'.

2. Holiday Inn Express & Suites Fort Myers Airport by IHG

Daniels Corridor

Amy

₩161,316 total

includes taxes & fees

Nov 13 - Nov 14

A Drury Inn & Suites hotel with a parking lot full of cars.

3. Drury Inn & Suites Fort Myers Airport FGCU

Miromar Lakes

Giselia Dos Santos

₩176,984 total

includes taxes & fees

Dec 1 - Dec 2

A large, clear swimming pool with multiple lounge areas and palm trees.

4. Margaritaville Beach Resort Fort Myers

Fort Myers Beach

Anastasia

₩333,348 total

includes taxes & fees

Nov 29 - Nov 30

An outdoor patio with a barbecue area, seating, and string lights.

5. Homewood Suites by Hilton Fort Myers Airport/FGCU

Miromar Lakes

Leo

₩184,094 total

includes taxes & fees

Nov 22 - Nov 23

A modern kitchen area with a breakfast bar, fruit display, and a chalkboard menu.

6. Hampton Inn Fort Myers Downtown

Fort Myers River District

Jason

₩168,313 total

includes taxes & fees

Nov 29 - Nov 30

A modern kitchen with a breakfast bar, various food items, and a chalkboard menu.

7. Hampton Inn & Suites Fort Myers - Colonial Blvd

Fort Myers

Bibi

₩151,084 total

includes taxes & fees

Nov 29 - Nov 30

A spacious lobby with a staircase, seating area, and a large wall-mounted screen.

8. Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Daniels Corridor

Merlin

₩97,727 total

includes taxes & fees

Nov 3 - Nov 4

A hotel room with a bed, a desk, a chair, and a small table.

9. SpringHill Suites by Marriott Fort Myers Airport

Daniels Corridor

Maria

₩132,039 total

includes taxes & fees

Nov 29 - Nov 30

An indoor swimming pool with clear water, a lifeguard station, and a seating area with chairs.

10. Comfort Inn & Suites Fort Myers Airport

Daniels Corridor

Erika

₩110,631 total

includes taxes & fees

Nov 30 - Dec 1

An outdoor patio with yellow chairs and red umbrellas, a fire pit, and a modern building in the background.

11. Home2 Suites by Hilton Fort Myers Airport

Fort Myers

Donna

₩181,729 total

includes taxes & fees

Nov 22 - Nov 23

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

12. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Caloosahatchee

Gabriel

₩148,738 total

includes taxes & fees

Nov 3 - Nov 4

A modern hotel lobby with a wooden floor, leather armchairs, a round table, and a large abstract painting on the wall.

13. Extended Stay America Premier Suites - Fort Myers - Airport

Daniels Corridor

Isaura

₩101,716 total

includes taxes & fees

Nov 3 - Nov 4

A reception area with a modern design, featuring a wooden panel wall with integrated lighting, a reception desk, and a refrigerator stocked with beverages.

14. Comfort Suites Fort Myers East I-75

Fort Myers

Eloan

₩129,149 total

includes taxes & fees

Nov 22 - Nov 23

A multi-level hotel atrium with balconies, seating areas, and a central courtyard.

15. Embassy Suites by Hilton Fort Myers Estero

Estero

Laura

₩193,925 total

includes taxes & fees

Nov 8 - Nov 9

16. Quality Inn & Suites Lehigh Acres Fort Myers

Lehigh Acres

arlene

₩87,934 total

includes taxes & fees

Nov 29 - Nov 30

A modern hotel lobby with wooden flooring, blue and beige chairs, and a patterned rug.

17. Hampton Inn Fort Myers-Airport & I-75

Daniels Corridor

marleen

₩150,450 total

includes taxes & fees

Nov 8 - Nov 9

A beach with a variety of seashells and pebbles.

18. Sanibel Island Beach Resort

Mid Island

Pablo

₩333,181 total

includes taxes & fees

Nov 3 - Nov 4

An outdoor patio area with a stone fire pit, seating, and string lights.

19. SpringHill Suites by Marriott Fort Myers Estero

Estero

siobhan

₩186,857 total

includes taxes & fees

Nov 13 - Nov 14

A multi-story hotel with a clear sky, palm trees, and a sign reading "HYATT PLACE".

20. Hyatt Place Fort Myers/at The Forum

The Forum

Daniel

₩141,301 total

includes taxes & fees

Nov 15 - Nov 16

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Vacation Rentals in Southwest Coast Florida

Aparthotel

A beach view from a balcony with a pool, palm trees, and a building with a balcony.

Edison Beach House

Fort Myers Beach

"One of the best locations on Ft Myers Beach"

Aparthotel

A beach with a thatched-roof structure, palm trees, and a view of the sea.

The Suites at Fishermen’s Village

Punta Gorda Isles

"Amazing place to stay when visiting Punta Gorda. Very convenient and loved having shops and restaurants so close by. Spacious unit - so much better than just a hotel room."

Apartment

A swimming pool with lounge chairs and a building with a sloped roof in the background.

Landing Apartments Fort Myers near Eastwood Village

Fort Myers

"Extremely clean, very easy check in. Everything is well maintained. Would definitely stay again."

Aparthotel

A modern hotel room with a kitchenette, a bed, a seating area, and a wardrobe.

StudioRes by Marriott Fort Myers Airport

Fort Myers

"Location was great."

Condo

A beach with the sun setting over the ocean, creating a calm and serene atmosphere.

Lovers Key Resort 403 by Distinctive Beach Rentals

Fort Myers Beach

"Amazing views, quiet, and saw plenty of dolphins and manatees from the balcony!!!! Will be staying again soon! "

Villa

A beachside area with colorful beach houses, a dock, and a sandy beach.

Matlacha Tiny Village

Matlacha

"So cute and clean nice dock to sit and relax or fish. Kayaks available to use free as well with life jackets paddles, etc. well equipped rental we can’t wait to go again! Great communication with hosts."

Apartment

A spacious living area with a curved ceiling, large windows, a dining area, and a kitchen.

Landing Furnished Apartments minutes from Downtown Fort Myers

Hancock

"Clean, quiet, perfect alternative to a hotel"

See all vacation rentals

Hotels recommended for families in Southwest Coast Florida

Best Western Fort Myers Inn & Suites

Fort Myers

₩114,282 total

includes taxes & fees

Nov 1 - Nov 2

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Stay near popular Southwest Coast Florida attractions

A lifeguard tower with an American flag, a green flag, and a signboard on a beach with people sunbathing and umbrellas.

Siesta Key Beach

9.6/10 (4,113 reviews)

The soft, white sand on Siesta Key’s award-winning family-friendly beach is perfect for relaxing under a sun umbrella and taking part in a game of volleyball.

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Learn more about Southwest Coast Florida

Amazing beaches, island views, and top sights from Key West Express to Siesta Key Beach—discover Southwest Coast Florida, a destination also famous for its live music scene.

See all hotels in Southwest Coast Florida

A sunset over a beach with a pier and people walking on the sand.

Top Southwest Coast Florida Hotel Reviews

Lani Kai Beachfront Resort

10/10 Excellent

"Great time, great location... Recommend highly .. we'll be back"

Sanibel Island Beach Resort

8/10 Good

"Overall good. Nice room. When we arrived the key to our room wouldn’t work. They gave us a different room and the keys wouldn’t work for that either. So we had to prop the door open if we left the room until the engineer arrived the next morning at 8:30. I finally called at 8:50 so we could leave to get breakfast and it was just an issue with the key programming. Bathroom fan stopped working (loud noise and light was flickering). Cable TV signal is iffy. The pool restaurant/bar is excellent. Location is great. Staff members were friendly."