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Top Luxury Southeastern Indiana Hotels

21c Museum Hotel Louisville

700 W Main Street Louisville KY

3 min walk from Louisville Slugger Museum

21c Museum Hotel Louisville is one of the Louisville luxury 4.5-star boutique properties where you can treat yourself to Champagne service, massage services, ...

9.4/10 Exceptional! (1,001 reviews)

"Very cool hotel with an art studio within it. Great staff. Great location. Great room and amenities."

Reviewed on Jun 24, 2026

West Baden Springs Hotel

8538 W Baden Ave West Baden Springs IN

2 hours drive from Louisville Slugger Museum

Treat yourself to a luxury stay at West Baden Springs Hotel, where you can enjoy amenities like plush bedding, designer toiletries, and more. Deluxe amenities ...

The Brown Hotel

335 W Broadway Louisville KY

16 min walk from Louisville Slugger Museum

The Brown Hotel is a Louisville luxury 4.5-star boutique property where you can pamper yourself with Egyptian cotton sheets, plush bedding, and more. The restaurant, ...

9.4/10 Exceptional! (1,252 reviews)

"Great experience! Staff was helpful and food/bar was great"

Reviewed on Jun 24, 2026

See all 1,137 properties in Southeastern Indiana

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.