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Top Luxury Southeastern Indiana Hotels

21c Museum Hotel Louisville

700 W Main Street Louisville KY

9 min walk from KFC Yum Center

21c Museum Hotel Louisville is one of the Louisville luxury 4.5-star boutique properties where you can treat yourself to Champagne service, massage services, ...

9.4/10 Exceptional! (1,006 reviews)

Located downtown next to all the great places to visit and eat. You can't go wrong staying here, the staff is wonderful and the food is great.

Reviewed on May 8, 2026

West Baden Springs Hotel

8538 W Baden Ave West Baden Springs IN

2 hours drive from KFC Yum Center

Treat yourself to a luxury stay at West Baden Springs Hotel, where you can enjoy amenities like plush bedding, designer toiletries, and more. Deluxe amenities ...

The Brown Hotel

335 W Broadway Louisville KY

14 min walk from KFC Yum Center

The Brown Hotel is a Louisville luxury 4.5-star boutique property where you can pamper yourself with Egyptian cotton sheets, plush bedding, and more. The restaurant, ...

9.4/10 Exceptional! (1,200 reviews)

I have stayed at The Brown Hotel many times and it has always been a pleasant experience. The staff are friendly and helpful. The hotel is clean and well maintained. The room was spacious with a sitting area. The bathroom was very clean.

Reviewed on May 10, 2026

See all 1,149 properties in Southeastern Indiana

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.