A large eye sculpture in a park surrounded by trees.

Northeast Missouri 2 Stars Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Northeast Missouri 2 Star Hotels

Tonight
Oct 6 - Oct 7
Tomorrow
Oct 7 - Oct 8
This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Our top choices for Northeast Missouri 2-star hotels

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.
A spacious indoor area with a high ceiling and large windows, featuring multiple seating areas with sofas and chairs, and a visible outdoor view through the windows.
A hotel room with a bed, a desk, a television, and a lamp.
A seating area with three grey armchairs and a central glass-top table, a wooden floor, and a view of parked cars through large windows.

1. Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
St. Ann
United States
Murphy
₩120,452
₩143,022 total
includes taxes & fees
Oct 20 - Oct 21
Pear Tree Inn St. Louis Airport
A modern kitchen with a hexagonal tile backsplash, built-in appliances, and a central island.
A pool table in a modern lounge area with a colorful geometric wall art and a seating area.
A tall building with a grid of windows and a sign that reads "HOME 2".
A modern office space with two hanging chairs, a desk, and a cabinet.

2. Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown
Downtown West
United States
Shonda
₩119,903
₩140,202 total
includes taxes & fees
Nov 1 - Nov 2
Tru By Hilton St. Louis Downtown
A hot tub with a wooden deck, surrounded by a bamboo fence, and string lights.
A spacious dining area with marble tables and chairs, a kitchen in the background, and a modern ceiling design.
A building with a brick facade, a covered entrance, and a tree adorned with string lights.
A spacious lobby with grey sofas, wooden coffee tables, and potted plants.

3. The West End

The West End
Central West End
United States
Sergio
₩110,998
₩156,559 total
includes taxes & fees
Oct 11 - Oct 12
The West End
A swimming pool area with red and white lounge chairs, a glass table, and a blue and yellow ceiling.
A hotel lobby with multiple seating areas, including booths and tables, and a check-in counter in the background.
A hotel room with a desk, chair, laptop, TV, and a large window with curtains.
A hotel room with a bed, a desk with a TV, a lamp, and a nightstand.

4. Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
St. Charles
United States
Socorro
₩159,209
₩182,967 total
includes taxes & fees
Oct 25 - Oct 26
Hampton Inn St. Charles St. Peters
A rooftop terrace with modern outdoor seating, a fire pit, and a view of the cityscape.
A modern bar area with multiple shelves of bottles, a bar counter, and several black bar stools.
A modern hotel exterior with a dark facade, outdoor seating area, and a sign indicating it is a Marriott hotel.
A spacious dining area with round tables, elegant chandeliers, and a city view.

5. AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton
Clayton
United States
anthony
₩171,853
₩200,619 total
includes taxes & fees
Oct 18 - Oct 19
AC Hotel St. Louis Clayton
A modern living area with a sofa, armchairs, a coffee table, and a kitchen in the background.
A modern living room with a sectional sofa, a round coffee table, and large windows offering a view of the city.
A large indoor pool with clear glass walls, a tiled edge, and a seating area with chairs and tables.
A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

6. Best Western St. Louis Inn

Best Western St. Louis Inn
St. Louis
United States
Harold
₩105,936
₩121,869 total
includes taxes & fees
Oct 20 - Oct 21
Best Western St. Louis Inn
A hotel with a prominent 'Comfort Suites' sign, a covered entrance with columns, and a parking lot.
A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.
A hotel lobby with a wooden floor, a reception desk, two armchairs, a sofa, and large windows with a view of buildings outside.
A lobby with a wooden floor, a reception desk, a seating area with a red sofa, and a glass door leading to another room.

7. Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
St. Charles
United States
Bryan
₩129,079
₩148,347 total
includes taxes & fees
Oct 18 - Oct 19
Comfort Suites St Charles - St Louis
A courtyard with outdoor seating, a central fountain, and a view of a tower.
The exterior of the Charles F. Knight Center with a stone facade, large arched entrance, and a sign above the doors.
A hotel room with two beds, a desk, and a chair.
A spacious lobby with a bar area, seating arrangements, and a clock on the wall.

8. The Knight Center at Washington University

The Knight Center at Washington University
St. Louis
United States
Rosalyn
₩226,407
₩260,338 total
includes taxes & fees
Oct 11 - Oct 12
The Knight Center at Washington University
A hotel room with a bed, a sofa, a coffee table, and wall art.
A hotel lobby with a reception desk, seating area, and a large potted plant.
A Sleep Inn & Suites hotel with a modern brick facade, a covered entrance, and a parking lot.
A restaurant with wooden tables and chairs, a blue wall with white floral patterns, and a counter with a coffee machine.

9. Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
O'Fallon
United States
Tim
₩106,247
₩125,319 total
includes taxes & fees
Oct 11 - Oct 12
Sleep Inn & Suites O'Fallon MO - Technology Drive
A hotel lobby with a tiled floor, white columns, a reception desk, and a view into the dining area.
A hallway with an exit sign, a vending machine, and a door.
A modern hotel room with a large bed, bedside lamps, a desk, and a chair.
A spacious lobby with a reception desk, seating area, and a large window.

10. Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO
Hazelwood
United States
Brehana
₩77,365
₩94,570 total
includes taxes & fees
Nov 3 - Nov 4
Motel 6 Hazelwood, MO
A brick building with a sign reading "Country Inn & Suites."
A modern kitchen with blue cabinetry, a central island with stools, pendant lighting, and a variety of kitchen appliances and utensils.
A spacious living room with a blue sofa, a white coffee table, and a striped armchair. There is a bookshelf filled with decorative items and a television on a wooden stand.
An indoor swimming pool with a tiled floor, a central window, and multiple chairs around the pool.

11. Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
St. Charles Historic District
United States
Roseanna
₩178,165
₩204,760 total
includes taxes & fees
Nov 1 - Nov 2
Country Inn & Suites by Radisson, St. Charles Historic District
A hotel room with a desk, a television, a bed, a mirror, and a coffee maker.
A reception area with a counter, a clock, and a sign indicating free Wi-Fi availability.
A Red Roof Plus hotel with a stone facade, a parking lot, and a covered outdoor area.
A Red Roof Plus hotel lobby with two leather chairs, a coffee station, and a sign indicating free Wi-Fi in all rooms.

12. Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 

Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 
The Hill
United States
Sean
₩100,442
₩117,447 total
includes taxes & fees
Nov 3 - Nov 4
Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 
An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.
A hotel entrance with a central fountain, large columns, and a clear sky.
A lobby with leather sofas, a fireplace, a flat-screen TV, and a reception desk.
A hotel room with a bed, desk, chair, and a bathroom with a bathtub.

13. Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
Hannibal
United States
Gayle
₩101,766
₩118,405 total
includes taxes & fees
Nov 1 - Nov 2
Quality Inn & Suites Hannibal West
A hotel room with a large bed, a bathtub, a television, and a window with curtains.
A compact kitchen with wooden cabinets, a refrigerator, a microwave, and a flat-screen TV on a wooden dresser.
A spacious living area with two grey sofas, a wooden coffee table, and a large mirror. There are potted plants and a ceiling fan.
A Days Inn hotel with a covered entrance, brick exterior, and a parking lot with cars.

14. Days Inn by Wyndham Downtown St. Louis

Days Inn by Wyndham Downtown St. Louis
Near North Riverfront
United States
Loreen
₩104,905
₩122,664 total
includes taxes & fees
Oct 25 - Oct 26
Days Inn by Wyndham Downtown St. Louis
A modern interior with a high ceiling, large windows, and a brick wall. There are orange chairs and a green sofa with orange cushions.
A modern building with a prominent entrance, large windows, and a covered parking area.
A modern indoor space with a large window, a seating area with sofas and chairs, and a dining area with tables and chairs.
A hotel room with a bed, a desk, a television, a sofa, and a lamp.

15. Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold
Arnold
United States
Lynda
₩120,452
₩139,243 total
includes taxes & fees
Oct 20 - Oct 21
Pear Tree Inn St. Louis Arnold
A spacious lobby with a staircase, a blue sofa, and a wooden table.
A gym with treadmills, weight machines, and a large potted plant.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A modern interior with a large window, a flat-screen TV mounted on a wall, and a seating area with colorful stools.

16. Quality Inn Foristell

Quality Inn Foristell
Foristell
United States
Aaron
₩118,320
₩133,643 total
includes taxes & fees
Oct 21 - Oct 22
Quality Inn Foristell
A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.
A corridor with snack bags, a refrigerator stocked with Mountain Dew, and a view into a room with a ceiling fan.
A modern lobby with blue seating, a reception desk, and large windows.
A modern dining area with a long table, multiple chairs, and a unique chandelier.

17. Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
Woodson Terrace
United States
Will
₩147,235
₩182,534 total
includes taxes & fees
Oct 21 - Oct 22
Hyatt Select St. Louis Airport
An indoor swimming pool with a no diving sign, surrounded by lounge chairs and gaming machines.
A hotel room with a large bed, a desk with a TV, a chair, a small table, and two wall-mounted lamps.
A restaurant with a patterned carpet, tables and chairs, a staircase, and a counter with a sign.
A restaurant with multiple tables and chairs, a bar area with a Bud Light sign, and a jukebox.

18. Days Inn by Wyndham Kirksville

Days Inn by Wyndham Kirksville
Kirksville
United States
Michael
Days Inn by Wyndham Kirksville
A hotel room with a bed, a sofa, a desk, and a lamp.
An indoor swimming pool with wooden walls, a tiled floor, and a sign indicating no diving is allowed.
A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.
A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.

19. Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
Hannibal
United States
Jerry
₩102,772
₩122,573 total
includes taxes & fees
Oct 11 - Oct 12
Comfort Inn & Suites - Hannibal
A hotel room with a bed, bedside table, lamp, TV, and a desk with a chair.
A kitchen with a built-in refrigerator, a coffee maker, and a microwave. There are cabinets and a countertop with various items on it.
A spacious lobby with a patterned tile floor, a staircase, and seating areas.
A reception area with a marble floor, a reception desk, and a sign that says "Quality."

20. Quality Inn Saint Louis Airport

Quality Inn Saint Louis Airport
Woodson Terrace
United States
Gordon
₩74,319
₩92,441 total
includes taxes & fees
Oct 25 - Oct 26
Quality Inn Saint Louis Airport
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 3-star hotels

Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Northeast Missouri.
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue St. Louis MO
₩122,916
₩143,490 total
Oct 25 - Oct 26
includes taxes & fees
9/10 Wonderful! (3,468 reviews)
Clayton Plaza Hotel & Extended Stay
Sonesta ES Suites St. Louis - Chesterfield

Sonesta ES Suites St. Louis - Chesterfield

15431 Conway Rd Chesterfield MO
₩131,976
₩153,084 total
Nov 4 - Nov 5
includes taxes & fees
Sonesta ES Suites St. Louis - Chesterfield
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

2211 Market Street St. Louis MO
₩139,503
₩163,120 total
Oct 11 - Oct 12
includes taxes & fees
8.8/10 Excellent! (2,235 reviews)
Pear Tree Inn St. Louis Near Union Station
Still don't see what you're looking for?
See all properties in Northeast Missouri.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Northeast Missouri

Great live music, sports teams, and popular sights from St. Louis Zoo to St. Louis Union Station—explore Northeast Missouri, a family-friendly destination also known for its theaters.

See all hotels in Northeast Missouri
A large eye sculpture in a park surrounded by trees.
Photo by Andrew Hershfeld

Top Northeast Missouri Hotel Reviews

The West End

The West End

10/10 Excellent
"The room and hotel was immaculate. Really nice to have secure off street parking in this area of stl. There are lots of small boutique restaurants in the area. The room was TINY! It served the purpose we needed it for."
John 1-night trip
Posted 1 day ago
The West End

Explore a world of travel with Expedia