Find hotels in Cairo, IL from ₩87,749

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Compare 23 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Quality Inn Cairo I-57
2.5 star property
6.6 out of 10, (271)
"We had a quiet and convenient one night stay. "
United States
Cindy
The price is ₩95,119
₩105,563 total
includes taxes & fees
Nov 7 - Nov 8
Quality Inn Cairo I-57
Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
6.6 out of 10, (602)
"Tracey Allen checked me in. She was great!"
United States
Timothy
The price is ₩79,063
₩87,749 total
includes taxes & fees
Nov 1 - Nov 2
Super 8 by Wyndham Charleston/Sikeston East MO
Quality Inn Charleston - Sikeston
2.5 star property
6.8 out of 10, (406)
"I consistently choose to stay there due to positive past encounters."
United States
IMTIAZ
The price is ₩94,017
₩104,335 total
includes taxes & fees
Nov 9 - Nov 10
Quality Inn Charleston - Sikeston
Eagle Inn Charleston
2.0 star property
6.8 out of 10, (102)
"Did not look like the picture at all! They charged an extra $50 for amenities that were not used. The room was not clean. There was cockroaches. There were semis next-door that started up at 4:30 in the morning, but at this point, we had no choice because we came in really late and there wasn’t anything else around. Will not stay there again."
United States
Natalie
The price is ₩103,877
₩115,282 total
includes taxes & fees
Nov 1 - Nov 2
Eagle Inn Charleston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Where is the best place for a stay in Cairo?
Based on our traveler data, Quality Inn Cairo I-57 is one of the top choices for your stay. This hotel offers free breakfast and free parking. Other good choices for your trip to the area are Super 8 by Wyndham Charleston/Sikeston East MO and Quality Inn Charleston - Sikeston. See all available top hotels, or vacation rentals in Cairo.
If I need to cancel my hotel reservation in Cairo, will I receive a refund?
Yes! Most hotel room reservations are refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Cairo.
Where can I learn more about changing or cancelling my trip to Cairo?
For more information about updating your trip to Cairo or cancelling it, head over to our customer service page.
Where is the best hotel to stay close to Fort Defiance?
Quality Inn Cairo I-57 is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located 4.9 mi (7.8 km) from Fort Defiance. Other good options around the area include Victorian Splendor in So. Illinois: wallmanor.com and Eagle Inn Charleston.
What's the best hotel for staying near Barkley Regional Airport (PAH)?
Drury Inn & Suites Paducah is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and an indoor pool. It's located 4.7 mi (7.6 km) from Barkley Regional Airport. Other choices close to the airport include La Quinta Inn & Suites by Wyndham Paducah and Baymont by Wyndham Paducah.
What is staying in Cairo like?
Visitors can enjoy all that Cairo has to offer including the restaurants, entertainment choices, and riverfront. This city also attracts tourists with its small-town vibe. A top sight in the city is Ohio River Valley. There are 23 hotels and other accommodations in the surrounding area. Find out more about Cairo.
What should I see while I'm in Cairo?
The picturesque setting of Ohio River Valley and Mississippi River exemplify the area's natural beauty. Additionally, you might want to add Fort Defiance State Park to your itinerary. Check out what more to see and do in Expedia's Cairo guide.
What's the seasonal weather like in Cairo?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Cairo is 61 inches.