Find hotels in Charleston, MO from ₩93,368

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Dec 19 - Dec 20
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Dec 20 - Dec 21
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Dec 19 - Dec 21
Next weekend
Dec 26 - Dec 28

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Our top choices for Charleston hotels

Front of property - evening/night
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (612)
"Staff was great! Room was nice. "
United States
Lana
The price is ₩91,677
₩101,730 total
includes taxes & fees
Dec 21 - Dec 22
Super 8 by Wyndham Charleston/Sikeston East MO
Desk, laptop workspace, blackout drapes, iron/ironing board
Quality Inn Charleston - Sikeston

Quality Inn Charleston - Sikeston

Quality Inn Charleston - Sikeston
2.5 star property
Charleston
6.8 out of 10, (406)
"The staff was very friendly and accommodating "
United States
Arturo
The price is ₩97,029
₩107,677 total
includes taxes & fees
Dec 28 - Dec 29
Quality Inn Charleston - Sikeston
Desk, iron/ironing board, free WiFi, alarm clocks
Eagle Inn Charleston

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.8 out of 10, (103)
"Middle of nowhere hotel was ok"
United States
David
The price is ₩89,300
₩99,102 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Eagle Inn Charleston
Basic Double Room | Free WiFi
La Center Motel

La Center Motel

La Center Motel
2.0 star property
La Center
7.8 out of 10, Good, (16)
"The place was very clean"
United States
Victoria
La Center Motel
Desk, free WiFi
Town House Inn Cape Giradreau

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
Cape Girardeau
6.0 out of 10, (206)
"Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors."
United States
Gary
The price is ₩81,195
₩94,851 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Town House Inn Cape Giradreau
Lobby
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1002)
"Nice place for a stay at a reasonable price."
United States
Arthur
The price is ₩103,325
₩116,567 total
includes taxes & fees
Dec 25 - Dec 26
Pear Tree Inn Cape Girardeau Near the Medical Center
Exterior
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.2 out of 10, Very Good, (882)
"Room was clean and spacious."
United States
George
The price is ₩113,674
₩136,360 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Candlewood Suites Cape Girardeau by IHG
Business center
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1003)
"Very friendly staff and great breakfast"
United States
Ray
The price is ₩132,850
₩149,857 total
includes taxes & fees
Dec 25 - Dec 26
Drury Inn & Suites Cape Girardeau
Standard Room, 1 Queen Bed, Non Smoking, Garden View | Free WiFi
Rockwood Inn

Rockwood Inn

Rockwood Inn
2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (18)
"We came into town for a concert and had a blast! The hotel was super comfy, and the staff were friendly. The rooms were very clean and the decor was beautiful! "
United States
Vanessa
The price is ₩221,941
₩250,370 total
includes taxes & fees
Dec 28 - Dec 29
Rockwood Inn
Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1001)
"Great place and staff, very accommodating!"
United States
Megan
The price is ₩132,850
₩149,857 total
includes taxes & fees
Dec 25 - Dec 26
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (139)
"Nice hotel, clean and comfortable "
United States
Laura
The price is ₩129,963
₩146,616 total
includes taxes & fees
Dec 28 - Dec 29
Fairfield Inn & Suites by Marriott Cape Girardeau
Courtyard
Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (784)
"Excellent stay"
United States
Christina
The price is ₩150,108
₩169,342 total
includes taxes & fees
Dec 25 - Dec 26
Hampton Inn Cape Girardeau I 55 East
Lobby
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

Pear Tree Inn Sikeston
2.5 star property
Sikeston
9.4 out of 10, Exceptional, (1001)
"Everything was clean, staff was friendly "
United States
Matthew
The price is ₩110,706
₩127,270 total
includes taxes & fees
Dec 24 - Dec 25
Pear Tree Inn Sikeston
Lobby sitting area
The Riverview

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (474)
"The room was clean and the mattress was extremely comfortable "
United States
Stacy
The price is ₩142,166
₩160,383 total
includes taxes & fees
Dec 22 - Dec 23
The Riverview
Lobby
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (468)
"The staff was very helpful and friendly. The rooms were modern and clean. The downtown location was perfect for us. "
United States
Deborah
The price is ₩171,248
₩194,048 total
includes taxes & fees
Dec 29 - Dec 30
Courtyard by Marriott Cape Girardeau Downtown
Lobby
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1000)
"Great stay"
United States
Heather
The price is ₩103,325
₩116,567 total
includes taxes & fees
Dec 25 - Dec 26
Pear Tree Inn Cape Girardeau West
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
"We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. "
United States
Brian
The price is ₩140,247
₩158,218 total
includes taxes & fees
Dec 25 - Dec 26
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Iron/ironing board, free WiFi, bed sheets
Country Yard Inn and Suite

Country Yard Inn and Suite

Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, (120)
"Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep."
United States
Andrew
The price is ₩78,892
₩93,861 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Country Yard Inn and Suite
Property amenity
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1001)
"Clean room, great location and friendly staff"
United States
Mark
The price is ₩132,850
₩152,735 total
includes taxes & fees
Dec 23 - Dec 24
Drury Inn & Suites Sikeston, MO
1 bedroom, desk, laptop workspace, blackout drapes
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1001)
"A great stay in every aspect. "
United States
Gertrude
The price is ₩92,858
₩105,834 total
includes taxes & fees
Dec 28 - Dec 29
Days Inn and Suites by Wyndham Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Charleston

Quaint Charleston is calling! Discover its opera, entertainment, cathedral, and more.

See all hotels in Charleston
Cypress Trees on the Horizon. A sting of cypress trees of various sizes extend across the horizon as the sunken sun paints the multicolored sky.

Top Charleston Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"Didn’t eat the breakfast but I’m sure it is wonderful. Everything from the Check in process to the condition of the rooms to the comfort of the stay was worth the money "
Corrie 1-night trip
Posted 1 day ago
Drury Plaza Hotel Cape Girardeau Conference Center

More cheap stays in Charleston

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO
The price is ₩92,858 per night from Dec 28 to Dec 29
₩92,858
₩105,834 total
Dec 28 - Dec 29
includes taxes & fees
7.2/10 Good! (1,003 reviews)

Frequently asked questions

Where is the best place for a stay in Charleston?
Quality Inn Charleston - Sikeston is a favorite with Expedia customers. This hotel offers free breakfast and free parking. Reviews from our site also recommend Super 8 by Wyndham Charleston/Sikeston East MO and Eagle Inn Charleston as top options for your trip. See all available top hotels, or vacation rentals in Charleston.
If I need to cancel my hotel reservation in Charleston, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Charleston.
Where can I learn more about changing or cancelling my trip to Charleston?
To find more details about changing or cancelling your trip to Charleston, click here.
What's the best pet-friendly hotel in Charleston?
Quality Inn Charleston - Sikeston is a top hotel for people traveling with their pets, and offers free WiFi for its human guests. Two other good options for you and your pet's trip include Super 8 by Wyndham Charleston/Sikeston East MO and Eagle Inn Charleston. See more pet-friendly hotel accommodations in Charleston.
What's the best accommodation near Lambert-St. Louis International Airport (STL)?
Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.
How is it to stay in Charleston?
Visitors to Charleston are sure to enjoy the restaurants. Tourists can also enjoy the city's entertainment choices, theaters, and churches. In Charleston, there are 3 hotels and other accommodations to choose from. Find out more about Charleston.
What are the top places to visit in Charleston?
The picturesque setting of Mississippi River and Ohio River exemplify the area's natural beauty. You'll also find Ballard Wildlife Management Area and Columbus-Belmont State Park in the area. Check out what more to see and do in Expedia's Charleston guide.
What's the seasonal weather like in Charleston?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Charleston is 59 inches.