Find hotels in East Prairie, MO from ₩99,332

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Our top choices for East Prairie hotels

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1,001 reviews)
"As always it was a perfect visit"
United States
John
The price is ₩135,475
₩155,762 total
includes taxes & fees
Mar 15 - Mar 16
Drury Inn & Suites Sikeston, MO

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (485 reviews)
"Very Clean room, friendly staff, breakfast in the morning. Will be staying again! "
United States
Affinity
The price is ₩143,842
₩162,865 total
includes taxes & fees
Mar 8 - Mar 9
Hampton Inn Sikeston

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.0 out of 10, Very Good, (49 reviews)
"Room clean bed comfortable, breakfast simple but good."
United States
James
The price is ₩96,515
₩110,244 total
includes taxes & fees
Mar 7 - Mar 8
Super 8 By Wyndham Marston

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (60 reviews)
"Clean rooms great staff"
United States
IRA
The price is ₩145,579
₩164,832 total
includes taxes & fees
Mar 5 - Mar 6
Fairfield Inn & Suites by Marriott Sikeston

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (447 reviews)
"Stay was excellent "
United States
Kourtney
The price is ₩125,960
₩142,619 total
includes taxes & fees
Mar 1 - Mar 2
Holiday Inn Express & Suites Sikeston Southwest by IHG

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very Good, (745 reviews)
"Parking was good, staff was great "
United States
Corey
New Orleans Inn Portageville

Country Hearth Inn & Suites Union City

Country Hearth Inn & Suites Union City
2.5 star property
Union City
8.6 out of 10, Excellent, (553 reviews)
"Very clean nice staff and well run "
United States
zach
The price is ₩103,765
₩123,224 total
includes taxes & fees
Feb 27 - Feb 28
Country Hearth Inn & Suites Union City

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (408 reviews)
"The staff was very friendly and accommodating "
United States
Arturo
The price is ₩100,897
₩111,970 total
includes taxes & fees
Mar 11 - Mar 12
The Riverstone Hotel Charleston-Sikeston

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (624 reviews)
"Affordable for a quick one night stay. Restaurant and gas station next to hotel."
United States
Annette
The price is ₩89,509
₩99,332 total
includes taxes & fees
Mar 3 - Mar 4
Super 8 by Wyndham Charleston/Sikeston East MO

Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America
2.5 star property
Union City
9.2 out of 10, Wonderful, (353 reviews)
"The rooms are big and the property is spotless!"
United States
debbie
The price is ₩102,915
₩122,212 total
includes taxes & fees
Mar 22 - Mar 23
Sleep Inn at Discovery Park of America

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.6 out of 10, (282 reviews)
"The quality was not what I expected for a "Quality Inn". It felt more light a Motel 6. I was not satisfied at all."
United States
ReShena
The price is ₩97,495
₩108,199 total
includes taxes & fees
Mar 6 - Mar 7
Quality Inn Cairo I-57

Hampton Inn Union City

Hampton Inn Union City
2.5 star property
Union City
9.6 out of 10, Exceptional, (172 reviews)
"Spotless , friendly staff."
United States
Gail
The price is ₩177,290
₩210,531 total
includes taxes & fees
Mar 5 - Mar 6
Hampton Inn Union City

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1,006 reviews)
"Great stay, everything was clean and comfortable. "
United States
Charles
The price is ₩117,602
₩134,034 total
includes taxes & fees
Mar 26 - Mar 27
Best Western Plus Sikeston I-55

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very Good, (740 reviews)
"Room was clean. Fairly quiet room. Front desk was kind. Would stay here again. ."
United States
Becky
The price is ₩94,396
₩107,588 total
includes taxes & fees
Mar 3 - Mar 4
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG
2.5 star property
Union City
9.4 out of 10, Exceptional, (313 reviews)
"The room was spacious & clean. The complimentary breakfast was nice. Very quiet place and next to a unique tourist attraction."
United States
Angela
The price is ₩148,750
₩176,642 total
includes taxes & fees
Mar 15 - Mar 16
Holiday Inn Express & Suites Union City by IHG

Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very Good, (287 reviews)
"The hotel was very clean, beds were comfortable, and staff was friendly and helpful."
United States
aileen
The price is ₩134,769
₩153,602 total
includes taxes & fees
Mar 15 - Mar 16
Comfort Inn & Suites Sikeston I-55

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1,001 reviews)
"Everything was excellent"
United States
James
The price is ₩104,003
₩118,538 total
includes taxes & fees
Feb 26 - Feb 27
Days Inn and Suites by Wyndham Sikeston

Hospitality House Union City I 69 / US 51

Hospitality House Union City I 69 / US 51
2.5 star property
Union City
6.8 out of 10, (381 reviews)
"Easy to check in.. Clean Room..Lots of food options near by.. "
United States
Pooran
The price is ₩87,679
₩104,111 total
includes taxes & fees
Mar 12 - Mar 13
Hospitality House Union City I 69 / US 51

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
Sikeston
6.8 out of 10, (595 reviews)
"Great place"
United States
Misty
The price is ₩91,003
₩103,743 total
includes taxes & fees
Feb 26 - Feb 27
Super 8 by Wyndham Sikeston/Miner Area

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (12 reviews)
"This hotel was great. Good location. Awesome staff. Hopefully I get the opportunity to stay here again."
United States
Jason
The price is ₩170,083
₩192,576 total
includes taxes & fees
Mar 26 - Mar 27
TownePlace Suites by Marriott Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular East Prairie attractions

Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artifacts tell the story of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

Bridge over Mississippi River, New Orleans in background

Top East Prairie Hotel Reviews

More cheap stays in East Prairie

Frequently asked questions

What's the best place for a stay in East Prairie?
Drury Inn & Suites Sikeston, MO, located 11.4 mi (18.4 km) from the heart of East Prairie, is a top choice for your stay based on our traveler data. Other good options for your visit to the area are Hampton Inn Sikeston and Days Inn and Suites by Wyndham Sikeston. See all available top hotels, or vacation rentals in East Prairie.
If I need to cancel my hotel reservation in East Prairie, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in East Prairie.
Where can I learn more about changing or cancelling my trip to East Prairie?
To access more information about rescheduling or cancelling your trip to East Prairie, click here.
What's the best hotel for staying near Cape Girardeau Municipal Airport (CGI)?
Candlewood Suites Cape Girardeau is one of the top choices for your stay and is a popular hotel, featuring an indoor pool and free WiFi. It's located 4.4 mi (7 km) from Cape Girardeau Municipal Airport.
What's it like to stay in East Prairie?
Visitors are sure to enjoy all that East Prairie has to offer. There are 33 hotels and other accommodations in the surrounding area. Find out more about East Prairie.
What should I do while I'm visiting East Prairie?
The picturesque setting of Big Oak Tree State Park and Mississippi River exemplify the area's natural beauty. You'll also find Central Park and New Madrid Historical Museum in the area. Check out what more to see and do in Expedia's East Prairie guide.
What's the weather like in East Prairie?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for East Prairie is 60 inches.