Find hotels in East Prairie, MO from ₩86,238

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Our top choices for East Prairie hotels

Best Western Plus Sikeston

Best Western Plus Sikeston
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1008)
"Great stay, everything was clean and comfortable. "
United States
Charles
The price is ₩97,314
₩110,915 total
includes taxes & fees
Jan 18 - Jan 19
Best Western Plus Sikeston

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (445)
"Stay was excellent "
United States
Kourtney
The price is ₩134,796
₩152,623 total
includes taxes & fees
Jan 25 - Jan 26
Holiday Inn Express & Suites Sikeston Southwest by IHG

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1000)
"Great place. Friendly staff clean"
United States
Jeff
The price is ₩130,433
₩149,957 total
includes taxes & fees
Jan 12 - Jan 13
Drury Inn & Suites Sikeston, MO

Pear Tree Inn Sikeston

Pear Tree Inn Sikeston
2.5 star property
Sikeston
9.4 out of 10, Exceptional, (1001)
"Very clean, very friendly! We will be staying again. "
United States
Beth
The price is ₩108,692
₩124,954 total
includes taxes & fees
Jan 13 - Jan 14
Pear Tree Inn Sikeston

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (459)
"Very clean and super friendly staff!"
United States
Katherine
The price is ₩148,797
₩168,475 total
includes taxes & fees
Jan 25 - Jan 26
Hampton Inn Sikeston

Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America
2.5 star property
Union City
9.2 out of 10, Wonderful, (328)
"The rooms are big and the property is spotless!"
United States
debbie
The price is ₩116,099
₩137,869 total
includes taxes & fees
Jan 14 - Jan 15
Sleep Inn at Discovery Park of America

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very Good, (733)
"Friendly sta"
United States
Melissa
New Orleans Inn Portageville

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very Good, (727)
"Clean room and easy access to room"
United States
Anne
The price is ₩80,428
₩91,667 total
includes taxes & fees
Jan 11 - Jan 12
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Country Hearth Inn & Suites Union City

Country Hearth Inn & Suites Union City
2.5 star property
Union City
8.6 out of 10, Excellent, (550)
"Roaches!"
United States
Teresa
The price is ₩114,780
₩136,304 total
includes taxes & fees
Jan 9 - Jan 10
Country Hearth Inn & Suites Union City

Quality Inn Union City US 51

Quality Inn Union City US 51
2.5 star property
Union City
8.4 out of 10, Very Good, (490)
"Nice room"
Mexico
José Ricardo
The price is ₩97,329
₩115,577 total
includes taxes & fees
Feb 1 - Feb 2
Quality Inn Union City US 51

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
Sikeston
6.8 out of 10, (579)
"Great place"
United States
Misty
The price is ₩86,096
₩98,141 total
includes taxes & fees
Jan 11 - Jan 12
Super 8 by Wyndham Sikeston/Miner Area

Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG
2.5 star property
Union City
9.4 out of 10, Exceptional, (310)
"Rooms were spotless and comfortable. The bathroom had all the amenities. Great view. Awesome buffet breakfast to wake up to. "
United States
Rickey Smith
The price is ₩144,942
₩172,118 total
includes taxes & fees
Feb 6 - Feb 7
Holiday Inn Express & Suites Union City by IHG

Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very Good, (284)
"The hotel was very clean, beds were comfortable, and staff was friendly and helpful."
United States
aileen
The price is ₩128,129
₩146,034 total
includes taxes & fees
Jan 15 - Jan 16
Comfort Inn & Suites Sikeston I-55

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1001)
"A great stay in every aspect. "
United States
Gertrude
The price is ₩91,169
₩103,909 total
includes taxes & fees
Jan 11 - Jan 12
Days Inn and Suites by Wyndham Sikeston

Hampton Inn Union City

Hampton Inn Union City
2.5 star property
Union City
9.6 out of 10, Exceptional, (167)
"Staff was great. Room was ready and clean. "
United States
Robert
The price is ₩155,233
₩184,340 total
includes taxes & fees
Jan 18 - Jan 19
Hampton Inn Union City

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
2.5 star property
Sikeston
9.2 out of 10, Wonderful, (48)
"THE ROOM WAS SPOTLESS, CLEAN LOBBY, WARM AND LOT OF VARITY BREAKFAST, STAFF IS SO NICE."
United States
AHMAD
The price is ₩146,391
₩165,751 total
includes taxes & fees
Jan 15 - Jan 16
Fairfield Inn & Suites by Marriott Sikeston

Country Yard Inn and Suite

Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, (121)
"Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep."
United States
Andrew
The price is ₩77,457
₩92,155 total
includes taxes & fees
Jan 9 - Jan 10
Country Yard Inn and Suite

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (105)
"Middle of nowhere hotel was ok"
United States
David
The price is ₩87,675
₩97,299 total
includes taxes & fees
Jan 9 - Jan 10
Eagle Inn Charleston

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.0 out of 10, Very Good, (42)
"Great hotel, great staff"
United States
Dmitry
The price is ₩83,559
₩95,446 total
includes taxes & fees
Jan 11 - Jan 12
Super 8 By Wyndham Marston

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (11)
"Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again. "
United States
Scott
The price is ₩165,089
₩186,921 total
includes taxes & fees
Jan 18 - Jan 19
TownePlace Suites by Marriott Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular East Prairie attractions

Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artifacts tell the story of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

Bridge over Mississippi River, New Orleans in background

Top East Prairie Hotel Reviews

More cheap stays in East Prairie

Frequently asked questions

What's the best place for a stay in East Prairie?
Drury Inn & Suites Sikeston, MO, located 11.4 mi (18.4 km) from the heart of East Prairie, is a top choice for your stay based on our traveler data. Other good options for your visit to the area are Hampton Inn Sikeston and Best Western Plus Sikeston. See all available top hotels, or vacation rentals in East Prairie.
If I need to cancel my hotel reservation in East Prairie, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in East Prairie.
Where can I learn more about changing or cancelling my trip to East Prairie?
To access more information about rescheduling or cancelling your trip to East Prairie, click here.
What's the best hotel for staying near Cape Girardeau Municipal Airport (CGI)?
Candlewood Suites Cape Girardeau is one of the top choices for your stay and is a popular hotel, featuring an indoor pool and free WiFi. It's located 4.4 mi (7 km) from Cape Girardeau Municipal Airport.
What's it like to stay in East Prairie?
Visitors are sure to enjoy all that East Prairie has to offer. There are 32 hotels and other accommodations in the surrounding area. Find out more about East Prairie.
What should I do while I'm visiting East Prairie?
The picturesque setting of Big Oak Tree State Park and Mississippi River exemplify the area's natural beauty. You'll also find Sikeston Depot Museum and New Madrid Historical Museum in the area. Check out what more to see and do in Expedia's East Prairie guide.
What's the weather like in East Prairie?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for East Prairie is 60 inches.